supported by the National Natural Science Foundation of China(No.32222046,China);the Sichuan Science and Technology Program(Nos.2022NSFSC0823,2023NSFSC193,2022NSFSC0793,China);the 1·3·5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.ZYJC21022,China).
FMS-like tyrosine kinase 3(FLT3)is a viable and important therapeutic target for acute myeloid leukemia(AML).FLT3 internal tandem duplication(FLT3-ITD)mutations have been identified in approximately 30%of AML patients...
partially supported by Grants-in-Aid for Scientific Research(23H02440 and 23K27133 to J.G.);a Grant-in-Aid for Challenging Exploratory Research(22K19443 to J.G.)from the Japan Society for the Promotion of Science(JSPS).
FMS-like tyrosine kinase 3(FLT3)is a receptor tyrosine kinase expressed in hematopoietic cells.Internal-tandem duplication domain(ITD)mutation and tyrosine kinase domain(TKD)mutation are the two most common mutations ...
Objective To screen m6A modification-related genes,and to establish a prognostic model in patients with FLT3 mutated acute myeloid leukemia (AML),especially in older patients and to evaluate the prognostic efficiency ...