supported by National Key Research and Development Program of China(grant No.2022YFC0867500,2020YFA0712102);National Natural Science Foundation of China(grant No.82151224,82202492);Fundamental Research Funds for Central Universities(grant No.QNTD 2023-01);Nutrition and Care of Maternal&Child Research Project of Biostime Institute of Nutrition&Care(grant No.2023BINCMCF28);State Key Laboratory of Pathogen and Biosecurity of China(grant No.SKLPBS2438);State Key Laboratory of Component-based Chinese Medicine(grant No.CBCM2024204).
Traditional Chinese medicine has unique advantages in preventing and treating COVID-19,and Fuzheng Jiedu decoction(FZJDD)was reported to be effective against COVID-19 in clinical trials.To investigate the potential me...
supported by the National Natural Science Foundation of China(Beijing,China,grant nos.32125038)。
Background Subacute ruminal acidosis(SARA)causes an increase in endotoxin,which can induce immune and inflammatory responses in the ruminal epithelium of dair y cows.In non-ruminants,epigallocatechin-3-gallate(EGCG),a...
Innovation and Entrepreneurship Project for College Students in Changsha Medical University,Changsha Medical Education 2022(Project No.41-149)。
Objective:This investigation delineates the anti-cancer potency of epigallocatechin-3-gallate(EGCG)in an oral cancer mouse model,with a focus on its effect on T-cell activation.Methods:An oral cancer model was establi...
supported by grants from the National Natural Science Foundation of China(52372272,32201109,32360234);the National Key Research and Development Program of China(2022YFB4601402);the Guangdong Basic and Applied Basic Research Foundation(2022B1515120052,2021A1515110557);the Key Basic Research Program of Shenzhen(JCYJ20200109150218836);the Self-innovation Research Funding Project of Hanjiang Laboratory(HJL202202A002).The authors thank the help of Tong Qiu,Qinghua Hou and Ran Yu of the Wuhan University of Technology,Wuhan 430070,China.
Chronic diabetic wounds are the most common complication for diabetic patients.Due to high oxidative stress levels affecting the entire healing process,treating diabetic wounds remains a challenge.Here,we present a st...
Chronic pancreatitis (CP) is a progressive inflammatory disorder of the pancreas. It is predominantly idiopathic (with an unknown cause) in India and mostly due to alcohol in the West. Diabetes that occur secondary to...
The article was financially supported by UGC SAP Programme,University of Madras,Chennai,India.
Objective:To explore the combinatorial effect of epigallocatechin-3-gallate(EGCG)and calorie restriction on activation of nuclear factor erythroid 2-related factor 2(Nrf2),a transcription factor involved in the antiox...
The authors regret the incorrect publication of Fig.5,which was not identified during the proofing stage.During a self-check,we unfortunately found that the insets(250μg/mL,1 day)in Fig.5b/c and the image(1000μg/mL,...
funded by the Universiti Tunku Abdul Rahman Research fund(IPSR/RMC/UTARRF/2019-C2/L08)。
Objective:To investigate the effect of epigallocatechin-3-gallate(EGCG)on endothelial dysfunction in spontaneously hypertensive rats(SHR).Methods:Wistar-Kyoto(WKY)rats and SHR were divided into four groups;WKY control...
funded by National Key Research and Development Program of China(2017YFA0105602,2018YFA0108700);NSFC Projects of INTERNATIONAL COOPERATION and Exchanges(81720108004);National Natural Science Foundation of China(81974019,82100275);Guangdong Provincial Special Support Program for Prominent Talents(2021JC06Y656);Science and Technology Planning Project of Guangdong Province(2020B1111170011,2022B1212010010);Guangdong special funds for science and technology innovation strategy,China(Stability support for scientific research institutions affiliated to Guangdong Province-GDCI 2021);Guangzhou Science and Technology Plan Project(202201000006);The Special Project of Dengfeng Program of Guangdong Provincial People’s Hospital(DFJH201812,KJ012019119,KJ012019423);The Marine Economy Development Project of Department of Natural Resources of Guangdong Province(No.GDNRC[2022]039).
Damaged skin cannot prevent harmful bacteria from invading tissues,causing infected wounds or even severe tissue damage.In this study,we developed a controlled-release antibacterial composite hydrogel system that can ...