GEMCITABINE

作品数:313被引量:907H指数:11
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相关领域:医药卫生更多>>
相关作者:贾林巴一黄鼎智韩如冰李鸿立更多>>
相关机构:中山大学广州医学院天津医科大学广州市第一人民医院更多>>
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相关基金:国家自然科学基金中国博士后科学基金广东省社会发展领域科技计划项目国家重点基础研究发展计划更多>>
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Combination of gemcitabine,pegaspargase,etoposide,and dexamethasone(GPED)in treatment of advanced extranodal NK/T-cell lymphoma被引量:1
《Chinese Medical Journal》2023年第6期732-734,共3页Ruiying Fu Yuanzheng Liang Liqiang Wei Xindi Liu Yingshi Piao Liang Wang 
National Natural Science Foundation of China(No.82170181);Beijing Hospitals Authority Youth Programme(No.QML20200201);Beijing Natural Science Foundation(No.7222027);CSH Young Scholars and 3SBioPharmaceutical joint research project(No.KYC2201001)
To the Editor:Extranodal natural killer/T-cell lymphoma(ENKTCL)is a highly aggressive lymphoma,closely associated with Epstein–Barr virus(EBV)infection.By using the combination of radiotherapy(RT)and asparaginase-bas...
关键词:LYMPHOMA chemotherapy EPSTEIN 
Efficacy of radical cystectomy plus adjuvant intraarterial chemotherapy with gemcitabine and cisplatin on locally advanced bladder cancer被引量:2
《Chinese Medical Journal》2014年第7期1249-1254,共6页Jiang Lijuan Zhang Zhiling Dong Pei Li Yonghong Yao Kai Liu Zhuowei Han Hui Qin Zike Yao Min Zhou Fangjian 
Background Bladder cancer is the ninth most common cancer in the world; fewer than 15% of transitional-cell carcinoma patients survive 2 years if left untreated.Although radical cystectomy is the standard treatment o...
关键词:adjuvant intraarterial chemotherapy adjuvant chemotherapy  bladder cancer radical cystectomy 
Efficacy and feasibility of gemcitabine and carboplatin as first-line chemotherapy in elderly patients with advanced non-small cell lung cancer被引量:2
《Chinese Medical Journal》2013年第24期4644-4648,共5页Kyu-Hyoung Lim Hui-Young Lee Seo-Young Song 
Background Although platinum-based chemotherapy is a standard first-line treatment in advanced non-small cell lung cancer (NSCLC), further research for the safety and efficacy of combination chemotherapy in elderly ...
关键词:GEMCITABINE CARBOPLATIN elderly  non-small cell lung cancer 
Tolerability and toxicity of adjuvant cisplatin and gemcitabine for treating non-small cell lung cancer被引量:4
《Chinese Medical Journal》2013年第11期2087-2091,共5页YANG Fan LI Xiao CHEN Ke-zhong JIANG Guan-chao WANG Jun 
Background The combination of cisplatin and vinorelbine is an evidence-supported regimen for adjuvant chemotherapy for treating non-small cell lung cancer (NSCLC). But this doublet has considerable toxicity and unfa...
关键词:non-small cell lung cancer adjuvant drug therapy TOXICITY TOLERABILITY 
Long-term outcomes of gemcitabine and cisplatin in patients with recurrent or metastatic esophageal squamous cell carcinoma: a phase Ⅱ trial被引量:11
《Chinese Medical Journal》2011年第23期4012-4017,共6页HUANG Jing FAN Qing-xia CHEN Li LIU Ai-na CAI Rui-gang HAO Xue-zhi WANG Jin-wan SUN Yan 
Background Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Prior studies had demonstrated potential synergistic antitumor activity of gemcitabine in combination with cisplatin. Ther...
关键词:chemotherapy GEMCITABINE CISPLATIN esophageal cancer 
Silencing of high mobility group A1 enhances gemcitabine chemosensitivity of lung adenocarcinoma cells被引量:1
《Chinese Medical Journal》2011年第7期1061-1068,共8页CAO Yuan-dong HUANG Pei-lin SUN Xin-chen MA Jun JIN Zhi-liang CHENG Hong-yan XU Rui-zhi LI Fan QIN Shu-kui DENG Yu-xia GE Xiao-lin 
Background The high mobility group A1 (HMGA1) proteins are architectural transcription factors found to be overexpressed in iung adenocarcinoma. Lentivirus-mediated RNA interference (RNAi) technology is a powerful...
关键词:RNA  small interfering high mobility group AI proteins APOPTOSIS CHEMOSENSITIVITY 
E1A, E1B double-restricted adenovirus enhances the cytotoxicity and antitumor activity of gemcitabine to renal cell carcinoma被引量:3
《Chinese Medical Journal》2011年第7期1082-1087,共6页WANG Hua Makoto Satoh CHEN Gui-ping LI De-chuan Hirofumi Hamada Yoichi Arai 
Background Our previous studies have demonstrated potent oncolysis efficacy of the E1A, E1B double-restricted replication-competent oncolytic adenovirus AxdAdB-3 for treatment of bladder cancer. Here, we reported the ...
关键词:ONCOLYSIS ADENOVIRUS GEMCITABINE renal cell carcinoma 
Relationship between single nucleotide polymorphisms in the deoxycytidine kinase gene and chemosensitivity of gemcitabine in six pancreatic cancer cell lines被引量:6
《Chinese Medical Journal》2011年第3期419-422,共4页SI Shuang LIAO Quan ZHAO Yu-pei HU Ya ZHANG Qiang YOU Li-li 
Background Single nucleotide polymorphisms (SNPs) in the deoxycytidine kinase (dCK) gene are associated with chemosensitivity to nucleoside analogs. 2',2'-Difluoro 2'-deoxycytidine (gemcitabine) is a first-li...
关键词:deoxycytidine kinase gene GEMCITABINE single nucleotide polymorphism CHEMOSENSITIVITY pancreatic neoplasm 
Gemcitabine and cisplatin treatment over a 3-week versus a 4-week dosing schedule: a randomized trial coducted in Chinese patients with nonsmall cell lung cancer被引量:3
《Chinese Medical Journal》2008年第10期892-897,共6页LIAO Mei-lin ZHU Yun-zhong LI Long-yun WAN Huan-ying YU Shi-ying Belinda HALL Teena WEST WANG Li 
Background Gemcitabine plus cisplatin is a standard treatment for stages IIIB and IV nonsmall cell lung cancer (NSCLC). This randomized phase Ⅱ study evaluated a 3-week versus a 4-week schedule of gemcitabine-cispl...
关键词:CHEMOTHERAPY GEMCITABINE CISPLATIN carcinoma  nonsmall cell lung 
Weekly gemcitabine as a radiosensitiser for the treatment of brain metastases in patients with non-small cell lung cancer:phase Ⅰ trial被引量:5
《Chinese Medical Journal》2007年第6期458-462,共5页HUANG Yu-juan WU Yi-long XIE Song-xi YANG Jing-ji HUANG Yi-sheng LIAO Ri-qiang 
This study was supported by the China Society of Clinical Oncology Foundation(No.Y-2005-0010)
Background Conventional treatment for non-small cell lung cancer (NSCLC) brain metastases (BM) is whole-brain radiotherapy (WBRT). The efficacy is limited. It might be increased by a potent radiosensitizer such ...
关键词:brain metastases radiosensitisation GEMCITABINE phase I study 
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