GEMCITABINE

作品数：313被引量：907H指数：11
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相关作者：贾林巴一黄鼎智韩如冰李鸿立更多>>
相关机构：中山大学广州医学院天津医科大学广州市第一人民医院更多>>
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Idarubicin-transarterial chemoembolization combined with gemcitabine plus cisplatin for unresectable intrahepatic cholangiocarcinoma
《World Journal of Gastrointestinal Oncology》2025年第4期81-92,共12页Cheng-Hao Zhao Huan Liu Tao Pan Zhan-Wang Xiang Lu-Wen Mu Jun-Yang Luo Chu-Ren Zhou Ming-An Li Ming-Ming Liu Hu-Zheng Yan Ming-Sheng Huang 
Supported by the Guangzhou Science and Technology Plan Project,No.2023A04J0419;National Natural Science Foundation Cultivation Project at the Third Affiliated Hospital of Sun Yat-sen University,No.2022GZRPYQN04.
BACKGROUND Intrahepatic cholangiocarcinoma(iCCA)is the second most common liver malignancy with poor prognosis and limited treatment options.AIM To identify the most effective drug for transarterial chemoembolization(...
关键词：Transarterial chemoembolization Intrahepatic cholangiocarcinoma GEMCITABINE CISPLATIN IDARUBICIN 
Exosome technology:A novel and effective drug delivery system in the field of cancer therapy
《World Journal of Gastrointestinal Oncology》2025年第3期464-469,共6页Jia-Xin Geng Yao-Fan Lu Jing-Nan Zhou Biao Huang Yuan Qin 
Natural Science Foundation of Zhejiang Province,No.LQ23H050005;Zhejiang Medical and Health Science and Technology Project,No.2023KY615;Scientific Research Project of Zhejiang Provincial Education Department,No.Y202250731 and No.Y202353130;the China Students’Innovation and Entrepreneurship Training Program,No.202310338044;China Postdoctoral Science Foundation,No.2022M721720.
In this article,we revisit an article,which specifically focuses on the utilization of exosomes derived from human bone marrow mesenchymal stem cells(MSCs)for targeted delivery of gemcitabine in pancreatic cancer trea...
关键词：EXOSOMES Drug delivery Mesenchymal stem cells Tumor therapy GEMCITABINE 
Exosomes as promising frontier approaches in future cancer therapy
《World Journal of Gastrointestinal Oncology》2025年第1期28-33,共6页Fatt-Yang Chew Chin-Hung Tsai Kuang-Hsi Chang Yu-Kang Chang Ruey-Hwang Chou Yi-Jui Liu 
Supported by the grants of China Medical University Hospital,No.DMR-112-173 and No.DMR-113-089;the grant from Tungs’Taichung Metro Harbor Hospital,No.TTMHH-R1120013.
In this editorial,we will discuss the article by Tang et al published in the recent issue of the World Journal of Gastrointestinal Oncology.They explored an innovative approach to enhancing gemcitabine(GEM)delivery an...
关键词：Mesenchymal stem cells EXOSOMES GEMCITABINE Pancreatic cancer APOPTOSIS 
Complete response of gallbladder cancer treated with gemcitabine and cisplatin chemotherapy combined with durvalumab:A case report and review of literature
《World Journal of Gastrointestinal Oncology》2025年第1期226-232,共7页Kai Chen Xu Feng Yuan Shi Xin-Lin Li Zheng-Rong Shi Xiang Lan 
Supported by General Project of Natural Science Foundation of Chongqing,China,No.cstc2021jcyj-msxmX0604;Chongqing Doctoral"Through Train"Research Program,China,No.CSTB2022BSXM-JCX0045.
BACKGROUND Gallbladder cancer(GBC)is the most common and aggressive subtype of biliary tract cancer(BTC)and has a poor prognosis.A newly developed regimen of gemcitabine,cisplatin,and durvalumab shows promise for the ...
关键词：Gallbladder cancer CHEMOTHERAPY IMMUNOTHERAPY Durvalumab Complete response Case report 
Human bone marrow mesenchymal stem cell-derived exosomes loaded with gemcitabine inhibit pancreatic cancer cell proliferation by enhancing apoptosis被引量：2
《World Journal of Gastrointestinal Oncology》2024年第9期4006-4013,共8页Zu-Gui Tang Tie-Mei Chen Yi Lu Zhe Wang Xi-Cheng Wang Yi Kong 
Guangdong Basic and Applied Basic Research Foundation,No.2019A1515011609;Project of Educational Commission of Guangdong Province of China,No.2018KQNCX124;Guangzhou Science and Technology Key Point Project,No.202103000041.
BACKGROUND Pancreatic cancer remains one of the most lethal malignancies,and has limited effective treatment.Gemcitabine(GEM),a chemotherapeutic agent,is commonly used for clinical treatment of pancreatic cancer,but i...
关键词：Mesenchymal stem cells EXOSOMES Extracellular vesicles GEMCITABINE Pancreatic cancer Drug delivery 
Verteporfin fluorescence in antineoplastic-treated pancreatic cancer cells found concentrated in mitochondria
《World Journal of Gastrointestinal Oncology》2024年第3期968-978,共11页Ying-Qiao Zhang Qing-Hao Liu Lu Liu Peng-Yu Guo Run-Ze Wang Zhi-Chang Ba 
BACKGROUND Traditional treatments for pancreatic cancer(PC)are inadequate.Photodynamic therapy(PDT)is non-invasive,and proven safe to kill cancer cells,including PC.However,the mitochondrial concentration of the photo...
关键词：Photodynamic therapy Pancreatic cancer VERTEPORFIN MITOCHONDRIA CHEMOTHERAPY GEMCITABINE 
Paradigm shift of chemotherapy and systemic treatment for biliary tract cancer
《World Journal of Gastrointestinal Oncology》2023年第6期959-972,共14页Wattana Leowattana Tawithep Leowattana Pathomthep Leowattana 
Biliary tract cancers(BTC)are frequently identified at late stages and have a poor prognosis due to limited systemic treatment regimens.For more than a decade,the combination of gemcitabine and cis-platin has served a...
关键词：Biliary tract cancers Gemcitabine and cisplatin combination Fibroblast growth factor receptor 2 inhibitors Isocitrate dehydrogenase 1 inhibitors Neurotrophic tyrosine receptor kinase gene fusion inhibitors Immune checkpoint inhibitors Microsatellite instability high Infrigatinib Pemigatinib 
Pancreatic ductal adenocarcinoma: Treatment hurdles, tumor microenvironment and immunotherapy被引量：7
《World Journal of Gastrointestinal Oncology》2020年第2期173-181,共9页Panagiotis Sarantis Evangelos Koustas Adriana Papadimitropoulou Athanasios G Papavassiliou Michalis V Karamouzis 
Pancreatic ductal adenocarcinoma(PDAC)is one of the most lethal diseases,with an average 5-year survival rate of less than 10%.Unfortunately,the majority of patients have unresectable,locally advanced,or metastatic di...
关键词：Pancreatic ductal adenocarcinoma Tumor microenvironment IMMUNOTHERAPY GEMCITABINE TREATMENT Cancer stem cells 
FOLFIRINOX vs gemcitabine/nab-paclitaxel for treatment of metastatic pancreatic cancer: Single-center cohort study被引量：1
《World Journal of Gastrointestinal Oncology》2020年第2期182-194,共13页In Rae Cho Huapyong Kang Jung Hyun Jo Hee Seung Lee Moon Jae Chung Jeong Youp Park Seung Woo Park Si Young Song Chansik An Mi-Suk Park Seungmin Bang 
BACKGROUND FOLFIRINOX and gemcitabine plus nab-paclitaxel(Gem+nabPTX)were recently introduced for metastatic pancreatic cancer treatment.However,studies that compared these two regimens and studies in Asian population...
关键词：Pancreatic cancer CHEMOTHERAPY FOLFIRINOX GEMCITABINE Nabpaclitaxel SURVIVAL 
Oral chemotherapy for second-line treatment in patients with gemcitabine-refractory advanced pancreatic cancer被引量：2
《World Journal of Gastrointestinal Oncology》2019年第11期1021-1030,共10页Se Jun Park Hyunho Kim Kabsoo Shin Myung Ah Lee Tae Ho Hong 
BACKGROUND There is no standard therapy for second-line treatment of gemcitabine-refractory pancreatic cancer patients with poor performance status.A combination of chemotherapy drugs 5-fluorouracil(5-FU),leucovorin,i...
关键词：PANCREATIC cancer Gemcitabine-refractory CAPECITABINE S-1 SECOND-LINE treatment 
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