GENE_POLYMORPHISMS

作品数:258被引量:907H指数:14
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相关作者:王增军王涛张炜李琼芳陈常中更多>>
相关机构:江苏省人民医院甘肃省肿瘤医院第二军医大学重庆医科大学附属第一医院更多>>
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Association and functional study of ATP6V1D and GPHN gene polymorphisms with depression in Chinese population
《World Journal of Psychiatry》2025年第4期73-85,共13页Peng Liang Jing-Jie Chen Xue Yang Rui Long Yue Li Zi-Ling Wang Ping-Liang Yang Yun-Dan Liang 
Supported by the Natural Science Foundation of Sichuan,China,No.2022NSFSC0778;Research Project Foundation of Sichuan Applied Psychology Research Center,No.CSXL-24202;Foundation of Sichuan Clinical Research Center for Geriatrics,No.24LHLNYX1-04 and No.24LHLNYX1-06;and the Key Laboratory Foundation for Development and Regeneration of Sichuan Province,No.24LHFYSZ1-25.
BACKGROUND Depression is a disease with a significant global social burden.Single nucleotide polymorphisms(SNPs)are correlated with the development of depression.This study investigates the relationship between polymo...
关键词:Single nucleotide polymorphism Genetic susceptibility DEPRESSION ATP6V1D GPHN 
Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis
《World Journal of Gastroenterology》2025年第7期156-159,共4页Shi Li Yue Xi Xue-Ying Dong Wen-Bin Yuan Jing-Feng Tang Ce-Fan Zhou 
Supported by National Natural Science Foundation of China,No.32270768,No.82273970,No.32070726,and No.82370715;National Key R&D Program of China,No.2023YFC2507904;the Innovation Group Project of Hubei Province,No.2023AFA026.
Hepatitis B virus remains a major cause of cirrhosis and hepatocellular carcinoma,with genetic polymorphisms and mutations influencing immune responses and disease progression.Nguyen et al present novel findings on sp...
关键词:Hepatitis B virus Gene polymorphisms Multi-clustering analysis Genetic markers Personalized medicine Clinical implications 
Clinical Value of ABCB1 and PAI-1 Gene Polymorphisms in Predicting Glucocorticoid-induced Adverse Reactions in Nephrotic Syndrome Patients
《Current Medical Science》2024年第5期923-931,共9页Ya-ling ZHAI Shuai-gang SUN Wen-hui ZHANG Hui-juan TIAN Zhan-zheng ZHAO 
supported by the General Project of Henan Natural Science Foundation(No.232300420034);the National Natural Science Foundation of China for the Youth(No.81600555);the General Project of China Postdoctoral Science Foundation(No.2018M640684)。
Objective Glucocorticoid(GC)-induced adverse reactions(ARs)have been extensively studied due to their potential impact on patients’health.This study aimed to examine the potential correlation between two polymorphism...
关键词:adenosine triphosphate-binding cassette B1 nephrotic syndrome plasminogen activator inhibitor-1 steroid-associated avascular necrosis of the femoral head steroid diabetes 
Research progress on gene polymorphisms related to the renin-angiotensin-aldosterone system and essential hypertension
《South China Journal of Cardiology》2024年第3期193-199,共7页WEI Jing-lian DONG Tian-wei YANG Guang-yuan WANG Wang RUAN Ming-yang NIU Tie-zheng 
supported by the Scientific Research Project of Heilongjiang Provincial Department of Health(No.20230303010126);the Excellent Scientific Research Team Project of the First Affiliated Hospital of Jiamusi University(No.202302)。
Background Essential hypertension(EH)is a complex polygenic genetic disease,which is the result of the interaction of multiple genetic factors,environmental factors,and risk factors.The susceptibility of inherited gen...
关键词:Essential hypertension Renin-angiotensin-aldosterone system Gene polymorphism 
Nucleotide excision repair gene polymorphisms and hepatoblastoma susceptibility in Eastern Chinese children:A five-center case-control study
《Chinese Journal of Cancer Research》2024年第3期298-305,共8页Huimin Yin Xianqiang Wang Shouhua Zhang Shaohua He Wenli Zhang Hongting Lu Yizhen Wang Jing He Chunlei Zhou 
supported by grants from the Innovation and Cultivation Fund Project of the Seventh Medical Center,PLA General Hospital(No.QZX-2023-7);Postdoctoral Science Foundation of China(No.2021M691649);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Nucleotide excision repair(NER)plays a vital role in maintaining genome stability,and the effect of NER gene polymorphisms on hepatoblastoma susceptibility is still under investigation.This study aimed to ev...
关键词:Nucleotide excision repair POLYMORPHISMS HEPATOBLASTOMA SUSCEPTIBILITY 
ALKBH5 gene polymorphisms and risk of neuroblastoma in Chinese children from Jiangsu Province
《Cancer Innovation》2024年第2期72-79,共8页Qian Guan Xinxin Zhang Jiabin Liu Chunlei Zhou Jinhong Zhu Haiyan Wu Zhenjian Zhuo Jing He 
Science,Technology and Innovation Commission of Shenzhen,Grant/Award Number:JCYJ20220531093213030;Postdoctoral Science Foundation of Jiangsu Province,Grant/Award Number:2021K524C;Postdoctoral Science Foundation of China,Grant/Award Number:2021M691649;National Natural Science Foundation of China,Grant/Award Numbers:82002636,82173593;Guangzhou Science and Technology Project,Grant/Award Numbers:202102020421,202201020622。
Background:Neuroblastoma is one of the most common extracranial malignant solid tumors in children.AlkB homolog 5(ALKBH5)is an RNA N6-methyladenosine(m6A)demethylase that plays a critical role in tumorigenesis and dev...
关键词:ALKBH5 NEUROBLASTOMA POLYMORPHISM SUSCEPTIBILITY 
Correction:Gene polymorphisms of molecules of the cGAS‑STING signalling pathway are associated with AML in Chinese patients
《Holistic Integrative Oncology》2024年第1期529-531,共3页Yuechan Ma Dongmei Wang Lei Feng Mengyuan Chang Mingying Li Guangqiang Meng Yuyan Wu Fei Lu Tao Sun Chunyan Ji Jingjing Ye 
Correction:Holist Integ Oncol 3,15(2024)https://doi.org/10.1007/s44178-024-00079-8 Following publication of the original article[1],the authors reported errors in Table 2,which have been corrected from.
关键词:patients corrected AML 
Gene polymorphisms of molecules of the cGAS‑STING signalling pathway are associated with AML in Chinese patients
《Holistic Integrative Oncology》2024年第1期539-548,共10页Yuechan Ma Dongmei Wang Lei Feng Mengyuan Chang Mingying Li Guangqiang Meng Yuyan Wu Fei Lu Tao Sun Chunyan Ji Jingjing Ye 
supported by grants from the Distinguished Taishan Scholars in Climbing Plan(tspd20210321);Taishan Scholars-Distinguished Experts(tstp20230653);the National Natural Science Foundation of China(82000165;82370165);the Key Program of Natural Science Foundation of Shandong Province(ZR2021MH302);the Horizontal Subject of Shandong University(6010121004).
Purpose The aim of this study was to explore the relationships between single-nucleotide polymorphisms(SNPs)of crucial molecules in the cGAS-STING signalling pathway and the susceptibility to,induction chemotherapy re...
关键词:Acute myeloid leukaemia cGAS-STING signalling pathway Single-nucleotide polymorphisms PROGNOSIS 
Association between Gene Polymorphisms and SNP-SNP Interactions of the Matrix Metalloproteinase 2 Signaling Pathway and the Risk of Vascular Senescence
《Biomedical and Environmental Sciences》2024年第2期146-156,共11页LIAO Zhen Yu YANG Shuo HU Song LIU Jia MAO Yong Jun SUN Shu Qin 
supported by the Construction of Prevention and Treatment System of Geriatric Syndromes Focusing on Disability and Dementia(No.21-1-2-2-zyyd-nsh)。
Objective This study aimed to explore the association of single nucleotide polymorphisms(SNP)in the matrix metalloproteinase 2(MMP-2)signaling pathway and the risk of vascular senescence(VS).Methods In this cross-sect...
关键词:Vascular senescence Pulse wave velocity(PWV) Single nucleotide polymorphism(SNP) Matrix metalloproteinase 2(MMP-2) Extracellular matrix(ECM) Structural degradation Multifactor dimensionality reduction(MDR) 
Association of ABCB1 gene polymorphisms rs1128503, rs2032582, rs4148738 with anemia in patients receiving dabigatran after total knee arthroplasty
《Chinese Journal of Traumatology》2024年第1期27-33,共7页Alina Kasimova Dmitry Labutin Anton Gvozdetsky Svetlana Bozhkova 
supported by the Vreden National Medical Research Center of Traumatology and Orthopaedics。
Purpose:Dabigatran is usually prescribed in recommended doses without monitoring of the blood coagulation for the prevention of venous thromboembolism after joint arthroplasty.ABCB1 is a key gene in the metabolism of ...
关键词:THROMBOPROPHYLAXIS P-GLYCOPROTEIN DABIGATRAN ANEMIA SNPs 
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