GENE_SILENCING

作品数：162被引量：627H指数：11
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Microbe-induced gene silencing explores interspecies RNAi and opens up possibilities of crop protection被引量：2
《Science China(Life Sciences)》2024年第3期626-628,共3页Rongxiang Fang 
In most eukaryotes, small RNA(sRNA)-mediated RNA silencing(or RNA interference, RNAi) is an evolutionarily conserved mechanism that regulates gene expression in a sequence-specific manner.Generally, s RNAs are produce...
关键词：protection CONSERVED MANNER 
Non-coding RNAs mediate the rearrangements of genomic DNA in ciliates被引量：2
《Science China(Life Sciences)》2013年第10期937-943,共7页FENG XueZhu GUANG ShouHong 
supported by grants from the National Basic Research Program of China(2011CBA01103);the National Natural Science Foundation of China(31171254);the Fundamental Research Funds for Central Universities(WK2060190018)
Most eukaryotes employ a variety of mechanisms to defend the integrity of their genome by recognizing and silencing parasitic mobile nucleic acids.However,recent studies have shown that genomic DNA undergoes extensive...
关键词：RNAi gene silencing scnRNA PIRNA rearrangement elimination 
Functions of chromatin remodeling factors in heterochromatin formation and maintenance被引量：1
《Science China(Life Sciences)》2012年第1期89-96,共8页BI Xin 
supported by U.S. National Institutes of Health (Grant No. GM62484)
Heterochromatin is characteristically more compact than chromatin is mediated by special histone modifications, euchromatin in the eukaryotic genome. The establishment of hetero- recruitment and propagation of heteroc...
关键词：chromatin remodeling gene silencing HETEROCHROMATIN INHERITANCE NUCLEOSOME REPLICATION 
Transient silencing mediated by in vitro synthesized double-stranded RNA indicates that PsCdc14 is required for sporangial development in a soybean root rot pathogen被引量：3
《Science China(Life Sciences)》2011年第12期1143-1150,共8页ZHAO Wei YANG XinYu DONG SuoMeng SHENG YuTing WANG YuanChao ZHENG XiaoBo 
supported by the Special Fund for Agro-Scientific Research in the Public Interest (Grant No. 3-20) from the Chinese government;the Priority Academic Program Development for Jiangsu Higher Education Institutions
In many eukaryotic organisms, Cdcl4 phosphatase regulates multiple biological events during anaphase and is essential for mitosis. It has been shown that Cdcl4 is required for sporulation in the potato blight pathogen...
关键词：Phytophthora sojae PsCdc14 SPORANGIUM transient gene silencing 
Caveolin-1 gene silencing promotes the activation of PI3K/AKT dependent on Erα36 and the transformation of MCF10A^(CE)被引量：17
《Science China(Life Sciences)》2010年第5期598-605,共8页FENG Shuang1,WANG Yang1,WANG Xi1,WANG ZhaoYi3,CUI YuYing1,LIU Jing4,ZHAO ChunHui1,JIN Mei1,2 & ZOU Wei1,2 1 College of Life Science,Liaoning Normal University,Dalian 116029,China 2 Liaoning Key Laboratory of Biotechnology and Molecular Drug R&D,Dalian 116029,China 3 Cancer Center,Creighton University,2500 California Plaza,Omaha,NE 68178,USA 4 First Clinical Hospital of Dalian Medical University,Dalian 116011,China 
supported by the National Natural Science Foundation of China (Grant No 30570225)
ERα36,a variant of estrogen receptor-α,acts as a dominant-negative factor in both estrogen-dependent and estrogen-independent transactivation signaling pathways,and is a key factor in the promotion,progression and p...
关键词：CAVEOLIN-1 ESTROGEN receptor PI3K/AKT 
Effect of cDNA fragments in different length derived from Potato Virus Y coat protein gene on the induction of RNA-mediated virus resistance被引量：5
《Science China(Life Sciences)》2004年第4期382-388,共7页ZHU Junhua ZHU Xiaoping WEN Fujiang BAI Qingrong ZHU Changxiang SONG Yunzhi 
This work was supported by the National Natural Science Foundation of China(Grant No.30270875);Shandong Province Natural Science Foundation(Grant No.Z2000D02);Shandong Province Science and Technology Development Project.
We have reported that cDNA derived from entire coat protein (CP) gene of potato virus Y (PVY) could induce resistance to PVY infection in transgenic tobacco plants, and the resistance was further demonstrated to be RN...
关键词：PVY partial length of CP gene fragments transgenic tobacco plants RNA-mediated resistance post-transcrip-tional gene silencing. 
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