云南高校图书馆联盟文献共享服务平台- GENE

GENE_TRANSFER: 作品数：204被引量：510H指数：11; 导出分析报告; 相关作者：王晶江洪黄从新李庚山李建军更多>>; 相关机构：武汉大学中国医学科学院阜外心血管医院大连民族大学青岛大学医学院附属医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划湖北省自然科学基金更多>>

Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase Gene Transfer Driver by KDR Promoter in Treatment of Experimental Human HepatocelLular Carcinoma in Nude Mice被引量：1: 《Chinese Journal of Cancer Research》2007年第1期22-26,共5页李宝金张超伊远学郝颖刘晓平区庆嘉; This project was supported by the National Natural Science Foundation of China (No. 30371386); by a grant from the Natural Science Foundation of Guangdong Province (No. 31010).; Objective： To investigate the therapeutic efficacy of adenovirus-mediated herpes simplex virus thymidine kinase （HSV-tk） gene transfer under the driving of KDR promoter （AdKDR-tk） in combination of ganciclovir （...; 关键词：Hepatocellular carcinoma KDR promoter Simpler virus Thymidine Kinase Adenovirus vector

THE ENHANCED GREEN FLUORESCENT PROTEIN AS A MARKER FOR HUMAN TUMOR CELLS LABELLED BY RETROVIRAL TRANSDUCTION: 《Chinese Journal of Cancer Research》2002年第2期126-130,共5页傅建新王玮白霞卢大儒阮长耿陈子兴; Objective: To investigate the feasibility of marking the human tumor cells with enhanced green fluorescent protein (EGFP) in vitro. Methods: The retroviral vector LGSN encoding EGFP was constructed and three human tum...; 关键词：Green fluorescent protein Gene transfer Retroviral vector Cultured tumor cells

LCRG1 SUPPRESSES TUMOR GROWTH IN VIVO BY LIPOSOME-MEDIATED GENE TRANSFER被引量：1: 《Chinese Journal of Cancer Research》2002年第2期113-117,共5页李友军章晓鹏陈主初何春梅段朝军; This work was supported by the National Natural Science Foundation of China(No. 39900052) and a grant from the Ministry of Health of PR China (No. 98-1-118).; Objective: To investigate whether LCRG1 (Laryngeal Carcinoma Related Gene 1) has tumor suppressor function. Methods: The recombinant plasmid pcDNA3.1(+)/LCRG1 was successfully constructed. The biological effects of LC...; 关键词：Laryngeal carcinoma (LC) LCRG1 Suppression tumor growth

SYNERGISTIC EFFICACY OF ADENOVIRUS-MEDIATED BCL-XS GENE TRANSFER AND TOPOTECAN IN OVARIAN CANCER CELL: 《Chinese Journal of Cancer Research》2001年第4期254-257,共4页王和 Vicki V Baker; This work was supported by a grant from the Science Foundation of National Committee of Education of China (No. 96361017).; Objective: To observe the synergistic efficacy between Adenovirus-mediated bcl-Xs(Adv-bcl-Xs) gene transfer and chemotherapy on ovarian cancer cell growth. Methods: NuTu-19 cells were infected by different titers of A...; 关键词：BCL-XS TOPOTECAN Ovarian Cancer

RETROVIRAL MEDIATED EFFICIENT TRANSFER ANDEXPRESSION OF MULTIPLE DRUG RESISTANCE GENE TO HUMAN LEUKEMIC CELLS被引量：6: 《Chinese Journal of Cancer Research》2000年第2期120-124,共5页傅建新王玮岑建军李建勇阮长耿陈子兴; a grant from the Public Health Bureau of Jiangsu Province (H9549).; Objective: To investigate retroviral-mediated transfer and expression of human multidrug resistance (MDR) gene MDR1 in leukemic cells. Methods: Human myeloid cells, K562 and NB4, were infected by MDR retrovirus from t...; 关键词：Gene transfer RETROVIRUS MDR genes Gene expression LEUKEMIA Cell lines

HIGH EFFICIENCY RETROVIRUS-MEDIATED GENE TRANSFERTO LEUKEMIA CELLS被引量：1: 《Chinese Journal of Cancer Research》1999年第1期8-12,共5页傅建新陈子兴岑建农王玮阮长耿; Objective: To establish an efficient and safe gene transfer system mediated by retrovirus for gene marking and gene therapy of human leukemia. Method: The retroviral vector LXSN, containing the neomycin resistance (Ne...; 关键词：RETROVIRUS LEUKEMIA Gene transfer TRANSFECTION Gene therapy Polymerase chain reaction

PRELIMINARY STUDY OF RETROVIRAL MEDIATED TRANSFER OF THE HUMAN mdr-1 GENE INTO MURINE AND HUMAN HEMATOPOIETIC STEM/PROGENITOR CELLS被引量：1: 《Chinese Journal of Cancer Research》1997年第4期36-39,共4页冯凯裴雪涛王立生高文谦徐黎王玉芝李梁吴祖泽; To investigate the characteristics of multidrugresistance and transplantation of modified stem/ progenitor cells by multidrugresistant gene (mdr1 gene), we established PA317/MDR1 cell line which producing retroviruse...; 关键词：Stem/progenitor cells mdr1 gene Gene transfer Retroviral mediated

IMMUNOLOGICAL CHARACTERISTICS OF THE LEUKEMIA CELLS TRANSFECTED WITH ONCOSTATIN M GENE BY RECOMBINANT ADENOVIRUS: 《Chinese Journal of Cancer Research》1997年第4期40-44,共5页王全兴曹雪涛弭静章卫平; In the present study, FBL3 murine erythroleukemia cells were transfected with human OSM(hOSM) gene by recombinant adenovirus, then the immunological properties of hOSM genetransfected FBL3 cells(FBL3OSM+) were investi...; 关键词：Oncostatin M Gene transfer ERYTHROLEUKEMIA IMMUNOGENICITY Costimulatory molecules CD14.

EFFECTS OF IL-6/IL-2 FUSION GENE TRANSFECTION ON TUMOUR CELL BIOLOGICAL CHARACTERISTICS IN VITRO AND IN VIVO: 《Chinese Journal of Cancer Research》1997年第4期49-52,共4页唐佩弦赵春华张明伟彭善云刘元林毛宁; In order to examine the feasibility of cytokine fusion gene transfer into tumor cells, a retroviral vector(pLXSN) for human interleukin 6/interleukin 2(IL6/IL2) fusion gene was constructed by using PCR and ligating th...; 关键词：Gene transfer Cytokinefusedgene ADHESION METASTASIS

IN VITRO AND IN VIVO CHEMOTACTIC EFFECT OF MIP-1a GENE TRANSFECTED TUMOR VACCINE ON IMMUNE EFFECTOR CELLS被引量：1: 《Chinese Journal of Cancer Research》1997年第4期13-17,共5页陈国友曹雪涛雷虹何龙周正芳; Vaccination with chemokine genetransfected tumor cells may be a new apporach to cancer treatment. Macrohage inflammatory protein1α (MIP1α) is a new type of chemokines which has chemotactic activity on effector c...; 关键词：Macrophage i nflammatory protein1α Gene transfer Cancer vaccine Effector cell Chemotaxis.

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