云南高校图书馆联盟文献共享服务平台- GENIC

GENIC: 作品数：139被引量：522H指数：10; 导出分析报告; 相关领域：农业科学医药卫生更多>>; 相关作者：张海清王斌李传友童哲王明更多>>; 相关机构：湖南农业大学中国科学院遗传与发育生物学研究所湖南隆平种业有限公司安徽省农业科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划中国博士后科学基金更多>>

Molecular and cellular mechanisms of photoperiod-and thermo-sensitive genic male sterility in plants: 《Molecular Plant》2025年第1期26-41,共16页Na Wang Xiang Li Jun Zhu Zhong-Nan Yang; supported by grants from the National Key R&D Program of China(2022YFF1003504);the National Natural Science Foundation of China(31930009 and 32100276);the Shanghai Pujiang Program(21PJ1411500).; Photoperiod-and thermo-sensitive genic male sterile(P/TGMS)lines display male sterility under high-temperature/long-day light conditions and male fertility under low-temperature/short-day light conditions.P/TGMS lines...; 关键词：P/TGMS lines POLLEN cell wall transition slow development ROS homeostasis

Anti-melanogenic properties of FBCC-EP850 derived from Carex pumila Thunb: 《Asian Pacific Journal of Tropical Biomedicine》2024年第11期477-485,共9页Mirissa Hewage Dumindu Kavinda Jinkuk Park Nayeong Kim Yung Hyun Choi Gi-Young Kim; supported by the Korea Environmental Industry&Technology Institute through Project to Make Multi-ministerial National Biological Research Resources more Advanced funded by Korea Ministry of Environment(RS-2021-KE001783).; Objective:To elucidate the anti-melanogenic potential of Carex pumila Thunb.extract(FBCC-EP850).Methods:A collection of 180 plant extracts was tested for inhibition of mushroom tyrosinase activity using an in vitro as...; 关键词：Carex pumila Thunb. MELANOGENESIS TYROSINASE cAMP-CREB-MITF signaling

Amylovis-201 is a new dual-target ligand,acting as an anti-amyloidogenic compound and a potent agonist of the σ_(1) chaperone protein: 《Acta Pharmaceutica Sinica B》2024年第10期4345-4359,共15页Laura Garcia-Pupo Lucie Crouzier Alberto Bencomo-Martinez Johann Meunier Axelle Morilleau Benjamin Delprat Marquiza Sablon Carrazana Roberto Menendez Soto del Valle Tangui Maurice Chryslaine Rodriguez-Tanty; supported by a PHC Carlos J.Finlay program from Campus France(project 47069SA)to TM and CRT.; The aggregation of Amyloid-β(Aβ)peptides is associated with neurodegeneration in Alzheimer's disease(AD).We previously identified novel naphtalene derivatives,including the lead compound Amylovis-201,able to form th...; 关键词：Alzheimer’s disease Amyloid-b aggregation Neuroprotection s1 receptor Drug discovery Molecular modelisation Zebrafish model Learning and memory

Cuproptosis mediates copper-induced testicular spermatogenic cell death: 《Asian Journal of Andrology》2024年第3期295-301,共7页Jing-Yi Zhang Xu-Jun Yu Jun-Jun Li Yao Xiao Guang-Sen Li Fang Yang Liang Dong; supported by the National Natural Science Foundation ofChina(No.81973647 and No.82274325);the Chengdu Municipal HealthCommission(No.2023215).; Cuproptosis,a novel mechanism of programmed cell death,has not been fully explored in the context of spermatogenic cells.Thisstudy investigated the potential involvement of cuproptosis in spermatogenic cell death usin...; 关键词：blood−testis barrier cuproptosis ferredoxin 1 spermatogenic cell death

Cand2 inhibits CRL-mediated ubiquitination and suppresses autophagy to facilitate pathogenicity of phytopathogenic fungi: 《Plant Communications》2024年第2期106-121,共16页Yunran Zhang Yunyun Wei Minghua Wu Mengyu Liu Shuang Liang Xueming Zhu Xiaohong Liu Fucheng Lin; supported by the National Natural Science Foundation of China (32270201,31972216,and 31970140);the Key Research and Development Project of Zhejiang Province,China (2021C02010);a Special Project for the Selection and Breeding of New Agricultural Varieties in Zhejiang Province,China (2021C02064);supported by the grant Organism Interaction from Zhejiang Xianghu Laboratory (to F.L.).; The ubiquitin–proteasome system and the autophagy system are the two primary mechanisms used by eukaryotes to maintain protein homeostasis,and both are closely related to the pathogenicity of the rice blast fungus.In...; 关键词：Magnaporthe oryzae AUTOPHAGY UBIQUITINATION PATHOGENICITY regulation mechanism phytopatho-genic fungi

Advances in the pathogenic, genetic and immunological studies of leprosy被引量：1: 《hLife》2024年第1期6-17,共12页Zihao Mi Hong Liu Furen Zhang; supported by Academic promotion programme of Shandong First Medical University(2019LJ002);the Natural Science Foundation of Shandong Province(ZR2023MH046);National Natural Science Foundation of China(82173430,82230107,82273545);the Innovation Project of Shandong Academy of Medical Sciences.; Leprosy is an infectious granulomatous disease caused by Mycobacterium leprae that affects the skin and can lead to deformity by damaging peripheral nerves.Although leprosy is no longer an incurable disease,its epidem...; 关键词：LEPROSY Mycobacterium leprae GENETICS IMMUNOLOGY

Impaired dNKAP function drives genome instability and tumorigenic growth in Drosophila epithelia: 《Journal of Molecular Cell Biology》2023年第12期50-64,共15页Ting Guo Chen Miao Zhonghua Liu Jingwei Duan Yanbin Ma Xiao Zhang Weiwei Yang Maoguang Xue Qiannan Deng Pengfei Guo Yongmei Xi Xiaohang Yang Xun Huang Wanzhong Ge; supported by the National Natural Science Foundation of China(31970668).; Mutations or dysregulated expression of NF-kappaB-activating protein(NKAP)family genes have been found in human cancers.How NKAP family gene mutations promote tumor initiation and progression remains to be determined....; 关键词：Drosophila wing imaginal disc dNKAP genome instability tumorigenic growth

The anti-oncogenic effect of 17-DMAG via the inactivation of HSP90 and MET pathway in osteosarcoma cells: 《Oncology Research》2023年第5期631-643,共13页MASANORI KAWANO KAZUHIRO TANAKA ICHIRO ITONAGA TATSUYA IWASAKI YUTA KUBOTA HIROSHI TSUMURA; supported in part by the fund of National Cancer Center Research and Development(26-A-4);the Grants-in-Aid for Scientific Research(Nos.15K10451,16K10866 and 16K20063)from Japan Society for the Promotion of Science.; Heat shock protein(HSP)90 plays a crucial role in correcting the misfolded three-dimensional structure of proteins,assisting them in folding into proper conformations.HSP90 is critical in maintaining the normal functi...; 关键词：OSTEOSARCOMA MET HSP90 17-DMAG

Spontaneous movement of a retrotransposon generated genic dominant male sterility providing a useful tool for rice breeding被引量：3: 《National Science Review》2023年第9期198-207,共10页Conghao Xu Yifeng Xu Zhengji Wang Xiaoyu Zhang Yuying Wu Xinyan Lu Hongwei Sun Lei Wang Qinglu Zhang Qinghua Zhang Xianghua Li Jinghua Xiao Xu Li Mingfu Zhao Yidan Ouyang Xianbo Huang Qifa Zhang; supported by the National Natural Science Foun-dation of China(31991223,91940301,31991222 and 31821005);the National Key Research and Development Program of China(2022YFF1002100);the Hubei Key R&D Program in Hongshan Lab(2021hszd005 and 2022hszd017);the Fundamental Re-search Funds for the Central Universities(2662023PY002).; Male sterility in plants provides valuable breeding tools in germplasm innovation and hybrid crop production.However,genetic resources for dominant genic male sterility,which hold great promise to facilitate breeding ...; 关键词：Oryza sativa dominant male sterility ribosome-inactivating protein RETROTRANSPOSON

Assessing the Pathogenic Ability of Six Species of Fusarium Genus on Onion Variety in Burkina Faso: 《Agricultural Sciences》2023年第6期739-750,共12页Kouka Hamidou Sogoba Tounwendsida Abel Nana Alassane Ouattara Mohamed Sana Bawomon Fidèle Neya Harouna Sawadogo Kadidia Koïta; Prema 178 onion variety is widely used in production in Burkina Faso. It is greatly appreciated but susceptible to basal rot. This study aimed to evaluate the pathogenic ability of six strains of Fusarium genus identi...; 关键词：Fusarium spp. PATHOGENICITY Allium cepa L. Burkina Faso

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