supported by the Key Project of Guangzhou City,No.202206060002;Science and Technology Project of Guangdong Province,No.2018B030332001;Guangdong Provincial Pearl River Project,No.2021ZT09Y552 (all to GC)。
Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders....
supported by Canada First Research Excellence Fund,Medicine by Design(to CMM)。
Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells c...
funding from the National Institutes of Health(GM008244 to J.F.R.,AG076322 and AG029796 to M.D.,AG048923,AG068030,AG074010,AG072562,and AG083258 to D.C.,and AG069768 and DK132849 to D.G.M.);the Department of Veteran Affairs(BX003380 and BX005934 to D.C.).
Identifying cellular mechanisms that underlie senescence development in vivo has been challenging in the field of aging research.In a recent article published in Nature,Byrns et al.identified a population of naturally...