HEPATITIS_B_VIRUS

作品数：1195被引量：6469H指数：33
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Hepatitis B virus genotype distribution and mutation patterns:Insights and clinical implications for hepatitis B virus positive patients
《World Journal of Experimental Medicine》2025年第2期72-82,共11页Manisha M Ratnaparkhi Chanda R Vyawahare Nageswari R Gandham 
Hepatitis B virus(HBV)infection is still a major worldwide health concern,contributing to chronic liver disorders like hepatocellular carcinoma(HCC).This review comprehensively analyzes HBV genotype distribution,mutat...
关键词：Chronic hepatitis Viral resistance Antiviral therapies Disease progression Personalized treatment 
Efficacy and Safety of Erzhu Jiedu Decoction Granules in Treating Mid-advanced Hepatitis B Virus-Associated Primary Liver Cancer Patients with Pi(Spleen)-Deficiency and Dampness-Heat Syndrome
《Chinese Journal of Integrative Medicine》2025年第5期394-401,共8页CHENG Yang WANG Hao-yi WAN Cheng-yi SHI Jie-wen JIN Yuan-yuan HE Sheng-li YIN Bao-bing CHEN Jian-jie 
Supported by Shanghai Municipal Science and Technology Commission Foundation(No.21Y11922800);National Natural Science Foundation of China(No.82374189)。
Objective:To assess the efficacy and safety of Erzhu Jiedu Decoction(EZJDD)Granules in treating mid-advanced hepatitis B virus-associated primary liver cancer(HBV-PLC)patients with Pi(Spleen)-deficiency and dampness-h...
关键词：Erzhu Jiedu Decoction Granules hepatitis B virus-associated primary liver cancer Pi(Spleen)-deficiency and dampness-heat syndrome 
Immune checkpoint inhibitors plus anti-angiogenesis in patients with resected high-risk hepatitis B virus-associated hepatocellular carcinoma
《World Journal of Gastrointestinal Oncology》2025年第4期116-130,共15页Jian-Lin Lu Yuan Cheng Zi-Ling Xu Gui-Xiang Qian Ming-Tong Wei Wei-Dong Jia 
Supported by the Key Research and Development Projects of Anhui Province,No.202104j07020048;National Key Research and Development Program of China,No.2022YFA1304500.
BACKGROUND Currently,there is a lack of effective adjuvant therapies for patients at high-risk of recurrent hepatitis B virus-associated hepatocellular carcinoma(HBV-HCC)after radical resection.Given the efficacy of a...
关键词：Hepatocellular carcinoma Hepatitis B virus Postoperative adjuvant therapy Immune checkpoint inhibitors ANTIANGIOGENESIS 
Dual therapy with nucleos(t)ide analogues in the prevention of hepatitis B virus recurrence after liver transplantation:Two case reports
《World Journal of Hepatology》2025年第4期144-150,共7页Nicolás Ortiz-López Maximiliano Acevedo Tamara Vergara Juan Pablo Roblero Álvaro Urzúa Máximo Cattaneo Jaime Poniachik 
BACKGROUND Infection by the hepatitis B virus(HBV)represents a significant global sociosanitary burden.While liver transplantation(LT)is an important therapeutic option,treatments that prevent HBV reinfection are nece...
关键词：Antiviral drug Liver transplant Hepatitis B virus Viral recurrence Nucleoside analog Case report 
Genetic intersection of human leukocyte antigen-DP/DQ and hepatitis B virus
《World Journal of Gastroenterology》2025年第16期101-103,共3页Jin-Wei Zhang 
Supported by National Natural Science Foundation of China,No.82170406 and No.81970238.
Hepatitis B virus infection remains a significant global health challenge,particularly in endemic regions like Vietnam.This article examines the groundbreaking study by Nguyen et al,which investigates the relationship...
关键词：Human leukocyte antigen Hepatitis B virus Hepatocellular carcinoma CIRRHOSIS Single nucleotide polymorphism Multi-clustering analysis VIETNAM 
Sequential activation of ERα-AMPKαsignaling by the flavonoid baicalin down-regulates viral HNF-dependent HBV replication
《Acta Pharmacologica Sinica》2025年第3期653-661,共9页Yi-jun Niu Cheng-jie Xia Xin Ai Wei-ming Xu Xiao-tong Lin Ying-qi Zhu Hai-yan Zhu Xian Zeng Zhong-lian Cao Wei Zhou Hai Huang Xun-long Shi 
supported by grants from the National Key Research and Development Program of China(No.2023YFC3503400);the National Nature Science Foundation of China(No.82074097);the Key Program of National Nature Science Foundation of China(No.82030113);Shanghai Science and Technology Funds(No.17ZR1401700);Shanghai Municipal Health Commission Project(No.201740200);Shanghai Engineering Research Center of Immunotherapeutics(No.19DZ2251400).
Baicalin(BA),a natural component found in many traditional Chinese medicines,exerts protective effects against several viruses.Although our previous studies have revealed that the anti-hepatitis B virus(anti-HBV)activ...
关键词：antiviral flavonoid BAICALIN hepatocyte nuclear factor hepatitis B virus ERa AMPKα 
Prevalence of transfusion transmissible infections among various donor groups:A comparative analysis
《World Journal of Virology》2025年第1期108-117,共10页Sanjay K Thakur Anil K Sinha Santosh K Sharma Aarzoo Jahan Dinesh K Negi Ruchika Gupta Sompal Singh 
BACKGROUND Transfusion transmissible infections(TTIs)are illnesses spread through contaminated blood or blood products.In India,screening for TTIs such as hepatitis B virus(HBV),hepatitis C virus(HCV),human immunodefi...
关键词：Blood donors Transfusion transmissible infections Hepatitis B virus Human immunodeficiency virus Hepatitis C virus Malaria parasite SYPHILIS 
Thyroid hormone,immunoglobin and complements for predicting hepatocellular carcinoma development in patients with hepatitis B virus-related liver cirrhosis
《World Journal of Hepatology》2025年第2期130-139,共10页Xue-Cheng Tong Kai Liu Ze-Yu Huang Xiu-Jun Zhang Yuan Xue 
Supported by The Research Foundation of Jiangsu Province Administration of Traditional Chinese Medicine,No.MS2023088;The Science and Technology Project of Changzhou,No.CE20225040;The Research Foundation of Nanjing Medical University Changzhou Medical Center,No.CMCC202311;Leading Talent of Changzhou“The 14th Five-Year Plan”High-Level Health Talents Training Project,No.2022CZLJ021.
BACKGROUND Hepatocellular carcinoma(HCC)surveillance is crucial for patients with compensated cirrhosis(CC)and decompensated cirrhosis(DC).Increasing evidence has revealed a connection between thyroid hormone(TH)and H...
关键词：Thyroid hormone IMMUNOGLOBULIN COMPLEMENT Hepatocellular carcinoma Prediction 
Hepatitis B virus confers innate immunity evasion through hepatitis B virus-miR-3 down-regulation of cGAS-Sting-IFN signaling
《World Journal of Hepatology》2025年第2期159-169,共11页Zhen-Yu Xu Jia-Shi Gao Ying He Xin-Qiang Xiao Guo-Zhong Gong Min Zhang 
Supported by National Natural Science Foundation of China,Key Project,No.82430071;The Scientific Research Program of FuRong Laboratory,No.2023SK2108;Clinical Medical Research Center for Viral Hepatitis of Hunan Province,No.2023SK4009;Hunan Provincial Natural Science Foundation,No.2023JJ60440;Hunan Provincial Health Commission Research Program,No.C202303088786.
BACKGROUND Hepatitis B virus(HBV)evades the innate immunity and leads to persistent chronic infection,but the molecular mechanism is still not well known.AIM To investigate whether HBV-miR-3 is involved in HBV immune ...
关键词：Hepatitis B virus HBV-miR-3 cGAS Sting IFN-Β 
New frontiers in hepatocellular carcinoma:Precision imaging for microvascular invasion prediction
《World Journal of Gastroenterology》2025年第8期155-160,共6页Liang Hao Zhao-Nan Zhang Shuang Han Shan-Shan Li Si-Xiang Lin Yan-Dong Miao 
Supported by Shandong Province Medical and Health Science and Technology Development Plan Project,No.202203030713;Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University,No.YTFY2022KYQD06。
This paper highlights the innovative approach and findings of the recently published study by Xu et al,which underscores the integration of radiomics and clinicoradiological factors to enhance the preoperative predict...
关键词：Microvascular invasion prediction Hepatocellular carcinoma Radiomics Precision imaging Hepatitis B virus 
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