HYPERINSULINISM

作品数:10被引量:12H指数:2
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相关领域:医药卫生更多>>
相关作者:王晓峰朱积川张小东黄晓波徐涛更多>>
相关机构:北京大学北京大学第一医院更多>>
相关期刊:《Open Journal of Molecular and Integrative Physiology》《World Journal of Gastroenterology》《Chinese Medical Journal》《World Journal of Diabetes》更多>>
相关基金:北京市自然科学基金更多>>
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Neonatal hyperinsulinism with an ABCC8 mutation:A case report
《World Journal of Clinical Cases》2023年第10期2254-2259,共6页Meng-Tong Liu Hui-Xia Yang 
BACKGROUND Neonatal hyperinsulinism can result from perinatal stress,genetic disorders,or syndromes,which can lead to persistent or intractable hypoglycemia in newborns.Mutations in the ABCC8 gene result in abnormal f...
关键词:NEWBORN HYPOGLYCEMIA Congenital hyperinsulinism ABCC8 Hyperglycemia in pregnancy Case report 
Concomitant dysregulation of androgen secretion and dysfunction of adipose tissue induced insulin resistance被引量:1
《World Journal of Diabetes》2022年第5期417-419,共3页Marwan SM Al-Nimer 
Hyperandrogenism and hyperinsulinemia have resulted from dysfunction of the theca cell of the ovary and adipose tissue and each one potentiates the other in patients with androgen excess disorders e.g.,polycystic ovar...
关键词:HYPERANDROGENISM HYPERINSULINISM Central triggers Polycystic ovary disease 
Molecular mechanisms of protein induced hyperinsulinaemic hypoglycaemia被引量:6
《World Journal of Diabetes》2014年第5期666-677,共12页Suresh Chandran Fabian Yap Khalid Hussain 
The interplay between glucose metabolism and that of the two other primary nutrient classes, amino acids and fatty acids is critical for regulated insulin secretion. Mitochondrial metabolism of glucose, amino acid and...
关键词:Hyperinsulinaemic hypoglycaemia KATP channel Glutamate dehydrogenase Hyperinsulinism/Hyperammonaemia syndrome Short-chain-3-hydroxyacyl-CoA dehydrogenase GLUTAMINE 
Age-dependent changes in the exocytotic efficacy in Kir6.2 ablated mouse pancreatic β-cells
《Open Journal of Molecular and Integrative Physiology》2012年第3期51-60,共10页Ernest Beaudelaire Tsiaze Ya-Chi Huang Lidija Krizancic Bombek Shi-Bing Yang Marko Jevsek Susumu Seino Marjan Slak Rupnik 
the Growbeta EU grant (5th framework, No. QLG1-CT-2001-02233);The European Neuroscience Institute Gottingen (ENI-G); Gottingen University Medical School; the Max-Planck-Society and Schering AG
In this study, we aimed to examine the electrophysio- logical properties of β-cells in Kir6.2-/- mice using fresh pancreatic tissue slice preparation. This prepa-ration is advantageous since it preserves socio-cellul...
关键词:Islets of Langerhans INSULIN HYPERINSULINISM Persistent Hyperinsulinemia Hypoglycemia of Infancy Ion Channels Patch-Clamp Techniques 
Protein causes hyperinsulinemia: a Chinese patient with hyperinsulinism/hyperammonaemia syndrome due to a glutamate dehydrogenase gene mutation
《Chinese Medical Journal》2010年第13期1793-1795,共3页CHEN Shi XIAO Xin-hua DIAO Cheng-ming TONG An-li WANG Ou QIU Zheng-qing YU Kang WANG Tong 
This study was supported by a grant from the Beijing Natural Science Foundation, China (No. 7092085).
Glucose is derived from three sources: intestinal absorption, glycogenolysis, and gluconeogenesis.Hypoglycemia in child is often attributed to depletion of glycogen stores. However, recently, congenital hyperinsulini...
关键词:hyperinsulinisrn/hyperammonaemia syndrome HYPERINSULINEMIA HYPOGLYCEMIA 
Paraneoplastic hyperinsulinism and secondary hypoglycaemia in a patient with advanced colon cancer: A rare association被引量:1
《World Journal of Gastroenterology》2008年第12期1952-1954,共3页Roberto Díaz Jorge Aparicio Andrea Mendizábal Marisa Faus Tania Fleitas Francisco Aparisi Maria Martín 
We review the case of a 74-year-old patient with ad-vanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was...
关键词:HYPOGLYCEMIA Colon cancer PARANEOPLASTIC HYPERINSULINISM Tumour markers 
Endocrine and metabolic effects of metformin in combination with compound cyproterone acetate in women with polycystic ovarian syndrome
《生殖医学杂志》2003年第z1期24-32,共9页叶碧绿 杨海燕 赵军招 林金菊 林文琴 
Objective:To study the endocrinologic and metabolic effects of metformin in combi-nation with compound cyproterone acetate (CPA) on patients with polycystic ovariansyndrome (PCOS).Methods: A prospective study involved...
关键词:POLYCYSTIC OVARY syndrome METFORMIN Ethinyl oestradiol/cyprot-erone acetate PILL HYPERINSULINISM 
Chronic Hyperinsulinism Induced Down-regulation of Insulin Post-Receptor Signaling Transduction in Hep G2 Cells被引量:1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2002年第4期313-316,共4页袁莉 Reinhard Ziegler Andreas Hamann 
DepartmentofEndocrinology,XieheHospital,TongjiMedicalCollege,Huazhong U niversity ofScienceandTechnology,Wuhan4 30 0 2 2
To study the regulatory effect of acute and chronic insulin treatmenton insulin post- re- ceptor signaling transduction pathway in a human hepatom a cell line (Hep G2 ) ,Hep G2 cells were incubated in the presence o...
关键词:INSULIN insulin signaling transduction insulin resistance 
Insulin sensitivity and the diffuseness of coronary artery disease in humans
《Chinese Medical Journal》2002年第12期1886-1888,156,共3页洪涛 赵国安 高炜 霍勇 朱国英 
OBJECTIVE: To study the relationship between insulin sensitivity and diffuse coronary artery disease. METHODS: Ninety-two consecutive patients underwent coronary angiography were enrolled in the study. Relationships b...
关键词:Insulin Resistance Aged Blood Glucose Coronary Circulation Coronary Disease FEMALE Humans HYPERINSULINISM LIPIDS Logistic Models Male Middle Aged 
Effect of surgical castration on risk factors for arteriosclerosis of patients with prostate cancer被引量:3
《Chinese Medical Journal》2002年第9期1336-1340,148-149,共5页徐涛 王晓峰 侯树坤 朱积川 张小东 黄晓波 
OBJECTIVE: To analyze the effect of castration on risk factors for arteriosclerosis of patients with prostate cancer. METHODS: Thirty patients with primary regional prostate adenocarcinoma limited to the prostate thec...
关键词:Aged ARTERIOSCLEROSIS Humans HYPERINSULINISM Insulin Resistance LIPIDS Male Middle Aged ORCHIECTOMY Prostatic Neoplasms Risk Factors 
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