云南高校图书馆联盟文献共享服务平台- HYPERINSULINEMIA

HYPERINSULINEMIA: 作品数：29被引量：115H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：贺克强更多>>; 相关机构：剑桥大学安徽省立医院耶鲁大学更多>>; 相关期刊：《Chinese Medical Journal》《World Journal of Cardiology》《World Journal of Diabetes》《Hepatoma Research》更多>>; 相关基金：上海市自然科学基金北京市自然科学基金河北省中医药管理局科研计划项目河北省科技厅科研项目更多>>

An overview of the physiopathology and various treatment strategies for polycystic ovary syndrome: 《Reproductive and Developmental Medicine》2024年第1期50-60,共11页Ayda Rajabi Soraya Babaie Behnaz Sadeghzadeh Oskouei Amir Mehdizadeh Azizeh Farshbaf-Khalili; Polycystic ovary syndrome(PCOS),a common endocrine disorder with metabolic and reproductive consequences,affects a significant percentage of women of reproductive age.Because of its complexity and impact on the qualit...; 关键词：Polycystic ovary syndrome Endocrine disorder HYPERANDROGENISM HYPERINSULINEMIA ANOVULATION AMENORRHEA

BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes: 《Journal of Molecular Cell Biology》2023年第5期21-37,共17页Rufeng Xu Kaiyuan Wang Zhengjian Yao Yan Zhang Li Jin Jing Pang Yuncai Zhou Kai Wang Dechen Liu Yaqin Zhang Peng Sun Fuqiang Wang Xiaoai Chang Tengli Liu Shusen Wang Yalin Zhang Shuyong Lin Cheng Hu Yunxia Zhu Xiao Han; supported by research grants from the National Natural Science Foundation of China(81420108007 and 81830024 to X.H.,82270844,82070843,and 81870531 to Y.Zhu).; Brain-specific serine/threonine-protein kinase 2(BRSK2)plays critical roles in insulin secretion andβ-cell biology.However,whether BRSK2 is associated with human type 2 diabetes mellitus(T2DM)has not been determined....; 关键词：type 2 diabetes mellitus genetic variant BRSK2 β-cell hypersecretion HYPERINSULINEMIA insulin resistance

Adult focalβ-cell nesidioblastosis:A case report: 《World Journal of Clinical Cases》2023年第1期150-156,共7页Kui Tu Li-Jin Zhao Jin Gu; BACKGROUND Nesidioblastosis usually refers to a series of clinical manifestations caused by the proliferation ofβ-cells in pancreatic islets,and these clinical manifestations are hyperinsulinemia and persistent hypog...; 关键词：Focal nesidioblastosis HYPERINSULINEMIA Persistent hypoglycemia Case report

Mechanism of insulin resistance in obesity: a role of ATP被引量：13: 《Frontiers of Medicine》2021年第3期372-382,共11页Jianping Ye; This work is supported by the National Key R&D Program of China(No.2018YFA0800603).; Obesity increases the risk of type 2 diabetes through the induction of insulin resistance.The mechanism of insulin resistance has been extensively investigated for more than 60 years,but the essential pathogenic signa...; 关键词：type 2 diabetes energy expenditure MITOCHONDRIA HYPERINSULINEMIA hyperglucagonemia AMPK

Role of insulin and insulin resistance in androgen excess disorders被引量：7: 《World Journal of Diabetes》2021年第5期616-629,共14页Kursad Unluhizarci Zuleyha Karaca Fahrettin Kelestimur; Insulin has complex effects on cell growth,metabolism and differentiation,and these effects are mediated by a cell-surface bound receptor and eventually a cascade of intracellular signaling events.Among the several me...; 关键词：INSULIN Insulin resistance HYPERINSULINEMIA HYPERANDROGENISM Androgen excess

Molecular links between non-alcoholic fatty liver disease and hepatocellular carcinoma被引量：4: 《Hepatoma Research》2019年第12期1-11,共11页Sana Raza Sangam Rajak Baby Anjum Rohit A.Sinha; This work was supported by the ICMR(59/05/2019/ONLINE/BMS/TRM)and Wellcome Trust/DBT India Alliance Fellowship(IA/I/16/2/502691)awarded to Sinha RA; Non-alcoholic fatty liver disease(NAFLD)and its advanced complication,non-alcoholic steatohepatitis(NASH),have become leading causes of hepatocellular carcinoma(HCC)worldwide.In this review,we discuss the role of meta...; 关键词：Non-alcoholic fatty liver disease non-alcoholic steatohepatitis hepatocellular carcinoma Gut microbiome DYSBIOSIS autophagy ER-STRESS ROS TNFα TLR-9 TLR-4 HYPERINSULINEMIA

Hyperinsulinemia,cancer and maqui berry:The promise of nutritional supplementation被引量：1: 《Food Science and Human Wellness》2019年第3期264-267,共4页Brett Deters Mir Saleem; Nutritional supplementation has long been studied as a possible treatment alternative or as an adjunct to the standard treatments for common ailments and diseases.According to the latest research,the Chilean maqui ber...; 关键词：HYPERINSULINEMIA Cardiovascular disease DIABETES INSULIN Maqui berry CANCER

Cognitive deficits and Alzheimer-like neuropathological impairments during adolescence in a rat model of type 2 diabetes mellitus被引量：10: 《Neural Regeneration Research》2018年第11期1995-2004,共10页Li Jin Yi-Pei Li Qiong Feng Li Ren Fang Wang Guo-Jia Bo Li Wang; principally supported by the Initial Funding of PhD Research from Henan Medical College of China,No.1001/0106;in parts by the Science and Technology Project of Henan Province of China,No.172102310105; Numerous studies have shown that many patients who suffer from type 2 diabetes mellitus exhibit cognitive dysfunction and neuronal synaptic impairments. Therefore, growing evidence suggests that type 2 diabetes mellit...; 关键词：nerve regeneration type 2 diabetes mellitus Alzheimer＇s disease monosodium glutamate neonatal period cognitive deficits HYPERGLYCEMIA HYPERINSULINEMIA insulin resistance neural regeneration

Effect of atorvastatin combined with metformin on the lipid metabolism, hyperinsulinemia and oxidative stress in patients with nonalcoholic fatty liver disease: 《Journal of Hainan Medical University》2017年第9期60-63,共4页Jie Zhang Lu Wang Bo Wu Ning Gao Ni Kang; Objective:To study the effect of atorvastatin combined with metformin on the lipid metabolism, hyperinsulinemia and oxidative stress in patients with nonalcoholic fatty liver disease (NAFLD).Methods:56 patients with N...; 关键词：Non-alcoholic FATTY liver disease ATORVASTATIN METFORMIN LIPID metabolism Oxidative stress

Influence of Thioctic Acid on the Hyperinsulinemia and Ovarian Volume in Female Patients with Polycystic Ovary Syndrome被引量：1: 《Open Journal of Endocrine and Metabolic Diseases》2015年第4期37-40,共4页L. A. Ivanova; 45 female patients with polycystic ovary syndrome took thioctic acid (Thioctacid-HR), 600 mg (n = 25) or high protein diet (n = 20). Fast insulin and glucose stimulus insulin were investigated before and after 3 month...; 关键词：Thioctic ACID HYPERINSULINEMIA POLYCYSTIC OVARY SYNDROME

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