INTERLEUKIN-1

作品数:157被引量:854H指数:16
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相关领域:医药卫生更多>>
相关作者:李晓玉魏伟张洁费晓方池岛乔更多>>
相关机构:安徽医科大学长春中医学院横滨市立大学首都医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金中国科学院科研项目更多>>
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Schnitzler syndrome and Schnitzler-like syndromes
《Chinese Medical Journal》2022年第10期1190-1202,共13页Cong-Qiu Chu 
Dr. Chu’s work was supported by the Innovative Award from the American College of Rheumatology Research Foundation and the VA Merit Review grant(No. I01BX005195)。
Schnitzler syndrome is a rare disease of adult-onset with main features including chronic urticarial rash, recurrent fever, arthralgia or arthritis, monoclonal gammopathy of undetermined significance (MGUS), and marke...
关键词:Schnitzler syndrome Schnitzler syndrome-like conditions INTERLEUKIN-1 Chronic urticarial rash 
CD23 mediated the induction of pro-inflammatory cytokines Interleukin-1 beta and tumor necrosis factors-alpha in Aspergillus fumigatus keratitis被引量:2
《Chinese Medical Journal》2021年第8期1001-1003,共3页Hai-Jing Yan Nan Jiang Li-Ting Hu Qiang Xu Xu-Dong Peng Hua Yang Wen-Yi Zhao Le-Yu Lyu Li-Mei Wang Cheng-Ye Che 
To the Editor:Fungal keratitis is primarily caused by pathogenic fungi species,such as Fusarium solani and Aspergillus fumigatus.The incidence of A.fumigatus has been increased worldwide.[1]Although new therapies have...
关键词:DRUGS diagnosis CD23 
Heparin inhibits burn-induced spleen cell apoptosis by suppressing interleukin-1 expression被引量:1
《Chinese Medical Journal》2014年第13期2463-2469,共7页Zhao Songfeng Zhang Xiao Zhang Xiaojian Shi Xiuqin Yu Zujiang Kan Quancheng 
Background Epidermal burn injury may trigger significant apoptosis of the spleen cells,which might be caused by a burninduced systemic inflammatory reaction.Heparin has been shown to possess anti-inflammatory properti...
关键词:BURN SPLEEN apoptosis HEPARIN INTERLEUKIN-1 
Correlation of tumor necrosis factor-β and interleukin-1 gene cluster polymorphism with susceptibility to bacteremia in patients undergoing kidney transplantation被引量:1
《Chinese Medical Journal》2013年第24期4603-4607,共5页WU Xiao-xia WAN Qi-quan YE Qi-fa ZHOU Jian-dang 
Background Bacteremia remains a significant cause of morbidity and mortality after kidney transplantation. This study was conducted to investigate whether the polymorphisms of tumor necrosis factor (TNF)-β, interle...
关键词:tumor necrosis factor-β interleukin-l β interleukin-1 receptor antagonist gene polymorphism BACTEREMIA kidney transplantation 
HIV-1B gp120 genes from one patient with AIDS dementia complex can affect the secretion of tumor necrosis factor and interleukin lp in glial cells被引量:1
《Chinese Medical Journal》2011年第24期4217-4222,共6页YAN Yu-fen WANG Zhi-yu PU Shuang-shuang WEN Hong-ling HUANG Tao SONG Yan-yan XU Hong-zhi ZHAO Li 
Background HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-a (TNF-a) and interleukin-113 (IL-113), which play major role in the neuronal death. It h...
关键词:HIV-1 envelop protein gp120 AIDS dementia complex cytokines interleukin-1 beta tumor necrosis factor-alpha 
Functional polymorphism in exon 5 and variant haplotype of the interleukin-1 receptor-associated kinase 1 gene are associated with susceptibility to and severity of sepsis in the Chinese population
《Chinese Medical Journal》2011年第15期2248-2253,共6页FANG Yu ZHANG Lu ZHOU Gang-qiao WANG Zhi-fu ZENG Zhao-shu LUO Zhi-yi LI Lei LIU Bao-chi 
This study was supported by the grants from the Chinese National Basic Research Program (No. 2005CB522602), Beijing Science & Technology NOVA Program (No. 2006A54) and National Natural Science Foundation of China (No. 31071100).
Background The interleukin-1 (IL-1) receptor-associated kinase 1 (IRAK1) is believed to play an important role in the pathogenesis of sepsis. Recent studies have suggested that the I RAK1 functional genetic varian...
关键词:SEPSIS interleukin-1 receptor-associated kinase 1 haplotype tagging single nucleotide polymorphisms linkage disequilibrium genetic association 
Interleukin-1 inhibits Sox9 and collagen type Ⅱ expression via nuclear factor-κB in the cultured human intervertebral disc cells被引量:12
《Chinese Medical Journal》2009年第20期2483-2488,共6页YU Zhan-ge XU Ning WANG Wen-bo PAN Shang-ha LI Ke-shen LIU Jia-kun 
The study was supported by a grant from the National Natural Science Foundation of China (No. 2004NSFC30471741).
Background The most significant biological change in intervertebral disc degeneration is the decrease of chondrocyte specific gene and protein expression of Sox9 and collagen type Ⅱ. Interleukin-1 (IL-1) is not exp...
关键词:INTERLEUKIN-1 SOX9 collagen type  nuclear factor-κB intervertebral disc cells 
UVB-irradiated human keratinocytes and interleukin-1■ indirectly increase MAP kinase/AP-1 activation and MMP-1 production in UVA-irradiated dermal fibroblasts被引量:22
《Chinese Medical Journal》2006年第10期827-831,共5页WANG Xiao-yong BI Zhi-gang 
This research was supported by a grant from National Natural Science Foundation of China (No. 30271195)
Background Solar ultraviolet (UV) irradiation induces the production of matrix metalloproteinases (MMPs) by activating cellular signalling transduction pathways. MMPs are responsible for the degradation and/or inh...
关键词:ultraviolet KERATINOCYTES FIBROBLASTS INTERLEUKIN-1Α matrix metalloproteinase-1 
IL-1α and ATP mRNA expression after ultraviolet lrradiation in human keratinocyte original-SCC 12F cells
《Chinese Medical Journal》2004年第4期581-585,共5页骆丹 闵玮 吴迪 苏忠兰 
Background Generally speaking, undifferentiated keratinocytes may synthesize a larger amount of IL-α and its production is decreased as cells complete differentiation gradually. Ultraviolet B (UVB) light can signigi...
关键词:Interleukin-1 · adenosine triphosphate · ultraviolet rays · keratinocytes 
Interleukin-1 gene polymorphism disease activity and bone mineral metabolism in rheumatoid arthritis被引量:1
《Chinese Medical Journal》2002年第1期46-49,145,共4页张晓中 L Llamado I Pillay P Price R Will 
Objective To determine whether interleukin-1α and 1β gene polymorphism is associated with rheumatoid arthritis disease activity and bone mineral metabolism, and whether there is any relationship between IL-1β an...
关键词:rheumatoid arthritis   ·   interleukin-1   ·   gene polymorphism   ·  disease activity   ·   bone mineral metabolism 
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