There is overwhelming evidence that functional gastrointestinal disorders(FGIDs) are associated with specific mechanisms that constitute important targets for personalized treatment. There are specific mechanisms in p...
Supported by the National Key Technology Support Program during "12th Five-Year Plan"Period of China,No.2014BAI08B00;the Leapforward Development Program for Beijing Biopharmaceutical Industry(G20),No.Z171100001717008
BACKGROUND Visceral hypersensitivity is considered to play a vital role in the pathogenesis of irritable bowel syndrome(IBS). Neurotrophins have drawn much attention in IBS recently. Brain-derived neurotrophic factor(...
One-hundred years have passed since the original description of the commonly described phenomenon of persistent abdominal symptoms being triggered by an acute enteric infection. This first account was generated out of...
Supported by National key Technology Support Program during the"12th Five-Year Plan"Period of China,No.2014BAI08B02
AIM To measure the leptin levels in patients with diarrheapredominant irritable bowel syndrome(IBS-D) and analyze the relationship of leptin with clinical features, visceral sensitivity, mast cells, and nerve fibers. ...
The aim of our study was to assess in our context, the efficacy of Rifaxim in improving the symptoms of irritable bowel syndrome particularly in its diarrheal (IBS-D) or mixed (IBS-DC) component and therefore assess i...
Supported by Medical and public health technology research and development projects of Wu Xi science and technology development fund,No.CSE31N1501
AIM To investigate the pharmacological effect of Tong XieYao Fang(TXYF) formula, a Chinese herbal formula, on Diarrhea-predominant irritable bowel syndrome(D-IBS) rats.METHODS In a neonatal maternal separation plus re...
Objective To investigate the significance and possible mechanism of food intolerance in diarrhea-predominant irritable bowel syndrome(IBS-D).Methods Twenty-seven IBS-D patients matched the RomeⅢcriteria were selected...
AIM: To determine effect of irritable bowel syndrome(IBS) subtype on IBS-specific quality of life(QOL) questionnaire and its subscales.METHODS: We studied IBS patients visiting our functional gastroenterology disorder...
美国FDA于2015年5月27日批准2种新药Viberzi(eluxadoline)和Xifaxan(rifaximin)用于治疗成人腹泻型肠易激综合征(irritable bowel syndrome with diarrhea,IBS-D)。肠易激综合征(IBS)患者常见的症状是腹部疼痛或不适。有研究估...
Gastrointestinal problems are common during wars, and they have exerted significant adverse effects on the health of service members involved in warfare. The spectrum of digestive diseases has varied during wars of di...