云南高校图书馆联盟文献共享服务平台- ISC

ISC: 作品数：340被引量：594H指数：12; 导出分析报告; 相关领域：自动化与计算机技术医药卫生更多>>; 相关作者：杨乃定姜继娇李保昆李志明赵建章更多>>; 相关机构：西北工业大学南京大学重庆本木科技有限公司大连理工大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国航空科学基金北京市自然科学基金国家社会科学基金更多>>

Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress: 《Neural Regeneration Research》2026年第1期333-345,共13页Yumei Liao Qinghua Zhang Qiaoyun Shi Peng Liu Peiyun Zhong Lingling Guo Zijian Huang Yinghui Peng Wei Liu Shiqing Zhang István Adorján Yumi Fukuzaki Eri Kawashita Xiao-Qi Zhang Nan Ma Xiaoshen Zhang Zoltán Molnár Lei Shi; supported in part by the National Key Research&Development Program of China,No. 2022YFA1104900 (to LS);the National Natural Science Foundation of China,Nos. 82371175, 82071535 (both to LS), 82101614 (to YP);the International Science and Technology Cooperation Projects of Guangdong Province,No. 2023A0505050121 (to LS);Guangdong Basic and Applied Basic Research Foundation,Nos. 2022B1515130007 (to LS), 2023A1515030012 (to SZ), 2022A1515010666 (to WL);the Science and Technology Program of Guangzhou,Nos. 202102070001 (to LS), 202201010041 (to YP);Shenzhen Basic Research Grant,Nos. JCYJ20200109140414636, JCYJ20230807145103007 (both to WL);awarded a Royal Society Newton Advanced Fellowship,No. AOMS-NAF0051003;in collaboration with Zoltán Molnár,Department of Physiology,Anatomy and Genetics,University of Oxford (2017–2021)。; Neuroserpin, a secreted protein that belongs to the serpin superfamily of serine protease inhibitors, is highly expressed in the central nervous system and plays multiple roles in brain development and pathology. As a...; 关键词：endoplasmic reticulum stress ischemia-reperfusion injury NEURON neuronal apoptosis NEUROPROTECTION NEUROSERPIN protein synthesis secretory protein stroke transcriptomic analysis

Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin: 《Neural Regeneration Research》2025年第5期1445-1454,共10页Meifeng Zheng Borui Zhang Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou; supported by STI2030-Major Projects,No.2022ZD0207600(to LZ);the National Natural Science Foundation of China,Nos.32070955(to LZ),U22A20301(to KFS);the Natural Science Foundation of Guangdong Province,No.2021A1515012197(to HO);Guangzhou Core Medical Disciplines Project,No.2021-2023(to HO);Key Research and Development Plan of Ningxia Hui Automomous Region,No.2022BEG01004(to KFS);Science and Technology Program of Guangzhou,China,No.202007030012(to KFS and LZ)。; Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitatio...; 关键词：ADIPONECTIN cerebral ischemia exercise pre-conditioning HIPPOCAMPUS memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise

Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration: 《Neural Regeneration Research》2025年第3期797-798,共2页Takayuki Nakagomi; partially supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (15K06723;18K07380);the Japan Agency for Medical Research and Development (AMED) (21nk0101538h0002) (to TN)。; Brain injuries like ischemic stroke induce endogenous stem cell production. Although the precise traits of stem cells in pathological brains remain unclear, we previously demonstrated that injury/ischemia-induced stem...; 关键词：ISCHEMIA INJURIES

Cerebral endothelial 3-mercaptopyruvate sulfurtransferase improves ischemia-induced cognitive impairment via interacting with protein phosphatase 2A: 《Acta Pharmaceutica Sinica B》2025年第1期314-330,共17页Li Zhu Yi Huang Jing Jin Rongjun Zou Rui Zuo Yong Luo Ziqing Song Linfeng Dai Minyi Zhang Qiuhe Chen Yunting Wang Wei Wang Rongrong He Yang Chen; supported by the National Natural Science Foundation of China(Grant numbers 82274130);Key Program of National Natural Science Foundation of China(Grant numbers 81930113);National TCM Inheritance and Innovation Team Project Foundation of China(Grant numbers ZYYCXTD-C202201);Key Laboratory of Heart and Spleen Related Diseases and Prescriptions Foundation of Guangdong Province(Grant number 2022B1212010012,China);the Guangzhou Basic and Applied Research Foundation(Grant number SL2023A04J01903,China);the Major Program of Science and Technology Foundation of Guangzhou(Grant number 202103000044,China).; The catalytic activity of 3-mercaptopyruvate(3MP)sulfurtransferase(MPST)converts 3MP to hydrogen sulfide(H_(2)S).However,the regulatory mechanisms governing MPST and its impact on the brain remain largely unexplored.O...; 关键词：Cerebral endothelium Protein phosphatase 2A 3-Mercaptopyruvate

基于改进沙猫群算法的水库群防洪优化调度研究: 《中国农村水利水电》2024年第12期43-51,共9页李淑敏冯丽云陈海涛; 2021年郑州市科技协同创新专项(202121206)。; 水库防洪调度对于有效减少洪水灾害、保障人民生命财产安全至关重要。此过程是个多阶段、非线性的、高纬度的工程问题,具有许多复杂的约束条件和相互依赖的决策变量。为了提高水库群优化调度问题的求解效率,充分发挥水库群协同防洪能力...; 关键词：水库群 SCSO算法 ISCSO算法防洪优化调度

Study on the Mechanism of miR-124-3p Regulating Cerebral Ischemia-Reperfusion Injury: 《Proceedings of Anticancer Research》2024年第6期24-30,共7页Zhongwei Zhang Yingying Li Shujuan Su Qiao Fu; Hainan Province Natural Science Foundation Youth Project“Research on the Mechanism of miR-124-3p Regulation of Cerebral Ischemia-Reperfusion Through the PI3K/Akt/mTOR Pathway”(Project No.820QN391)。; Objective: To investigate the role of miR-124-3p in ischemia-reperfusion injury following ischemic stroke and to evaluate the neuroprotective effects of miR-124-3p inhibition on neurological outcomes, infarct size, an...; 关键词：Ischemic stroke Ischemic-reperfusion injury miR-124-3p Neurological function Infarct volume

Photocatalytic Minisci-type multicomponent reaction for the synthesis of 1-(halo)alkyl-3-heteroaryl bicyclo[1.1.1] pentanes: 《Chinese Chemical Letters》2024年第10期6-8,共3页Rong-Nan Yi Wei-Min He; Bioisosteres play an important role in pharmaceutical and agricultural compound design that has been developed to enhance the properties of molecules.As a sp3-rich small ring cage hydrocarbons,bicyclo[1.1.1]pentanes(B...; 关键词：synthesis substituted ALKYL

Improvement of myocardial fibrosis injury by Shengmai injection in ischemia-induced heart failure in a rat model: 《Science of Traditional Chinese Medicine》2024年第3期245-253,共9页Yurong Ding Junying Wei Enhui Ji Menglan Wang Yue Wu Mengli Chang Yi Zhang Jing Xu; supported by the national key research and development program of China(2019YFC1708900);National Natural Science Foundation of China(82204973);scientific and technological innovation project of China Academy of Chinese Medical Sciences(CI2021B015);the fundamental research funds for the central public welfare research institutes of Institute of Chinese Materia Medica,China Academy ofChinese Medical Sciences(ZXKT21030);special program for outstanding,young scientific and technological talents(innovation)of China Academy of ChineseMedical Sciences(ZZ15-YQ-034).; Background:Heart failure(HF)is the leading cause of death worldwide.Myocardial infarction(MI)is a major contributor to HF.Shengmai injection(SMI)has exhibited protective efficacy in preventing HF.However,the advantage...; 关键词：Shengmai injection Proteomic profile Heart failure Myocardial fibrosis Myocardial infarction

Application of NSR-AISC Method in Reserve Estimation and Technical Economic Evaluation of Low-Grade Polymetallic Deposits: Taking a Low-Grade Copper-Molybdenum Mine in Guangdong Province as an Example: 《World Journal of Engineering and Technology》2024年第3期731-741,共11页Yao Xue Tengfei Li; The development and utilization of low-grade polymetallic deposits with strategic mineral resources is one of the important measures to alleviate the current high dependence on strategic mineral resources in China. Ho...; 关键词：NSR-AISC Method General Industrial Indicators Low-Grade Polymetallic Ore

基于IC曲线的锂电池早期ISC检测研究: 《电机与控制应用》2024年第8期30-38,共9页杨林陈则王徐肇凡; 航空科学基金资助项目(20183352030,201933052001)。; 锂离子电池内短路(ISC)是引发热失控事故的主要原因,ISC故障的早期识别对于降低火灾或爆炸相关的风险至关重要,传统的基于滤波容量增量曲线的检测方法容易受到干扰。针对如何提取容量增量曲线上的特征参数进行早期内短路检测问题,提出...; 关键词：锂电池容量增量曲线电压重构早期微内短路检测

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