ISCHEMIA-REPERFUSION

作品数:210被引量:1347H指数:17
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相关领域:医药卫生更多>>
相关作者:张均田陈永红杜冠华张玲妹孙凤艳更多>>
相关机构:中国医学科学院北京协和医学院上海医科大学中国药科大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金中国博士后科学基金湖北省自然科学基金国家教育部博士点基金更多>>
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Forkhead box K1 deficiency alleviates ischemia-reperfusion-induced acute kidney injury
《China Medical Abstracts(Internal Medicine)》2024年第3期176-177,共2页LI Chen 
Objective To investigate the effect and mechanism of forkhead box K1 (FOXK1) in acute kidney injury(AKI),and to provide new ideas and targets for preventing and treating AKI.Methods Three models of AKI were establishe...
关键词:C57BL/6 ISCHEMIA REPERFUSION 
Biochanin A,as the Lrg1/TGF-β/Smad2 pathway blockade,attenuates blood-brain barrier damage after cerebral ischemiareperfusion by modulating leukocyte migration patterns
《BIOCELL》2023年第8期1869-1883,共15页LONGSHENG FU JINFANG HU FENG SHAO YAOQI WU WEI BAI MINGJIN JIANG HAO CHEN LIHUA CHEN YANNI LV 
supported by a Foundation Project:National Natural Science Foundation of China(Nos.82100417,81760094),China;The Foundation of Jiangxi Provincial Department of Science and Technology Project(Nos.20202ACBL206001,20212BAB206022,20181BAB205026).
Background:Biochanin A is an excellent dietary isoflavone that has the concomitant function of both medicine and foodstuff.The attenuation function of biochanin A on blood-brain barrier(BBB)damage induced by cerebral ...
关键词:Biochanin A BLOCKADE Leukocyte migration Blood-brain barrier damage ISCHEMIA-REPERFUSION Lrg1 
Immunoglobulin-like domain-containing receptor 2 deficiency aggravates ischemia-reperfusioninduced renal fibrosis
《China Medical Abstracts(Internal Medicine)》2023年第2期112-113,共2页徐梦园 
Objective To investigate the role of immunoglobulinlike domain-containing receptor 2(Ildr2)in renal fibrosis induced by ischemia-reperfusion.Methods Ildr2 knockout mice(KO group)were constructed using CRISPR/Cas9 tech...
关键词:CRISPR/Cas9 ISCHEMIA REPERFUSION 
Contribution of Myocyte Apoptosis to Myocardial Injury in an in Vivo Rabbit Preparation of Ischemia-Reperfusion
《World Journal of Cardiovascular Diseases》2022年第8期426-438,共13页John G. Kingma 
Objective: Exposure of the heart to repeated, brief episodes of coronary occlusion/reperfusion prevents lethal myocyte injury. Necrosis and apoptosis, two seemingly distinct mechanisms of cell death caused by ischemia...
关键词:Ischemia REPERFUSION Ischemic Conditioning Necrosis APOPTOSIS DNA Fragmentation PARP Cleavage Rabbits 
The Effect of <i>Momordica charantia</i>on Ovarian Ischemia-Reperfusion
《Journal of Biosciences and Medicines》2021年第12期8-14,共7页Asir Firat Deveci Engin Gokalp Ozkorkmaz Ebru Şahin Fırat Ermiş Işılay Sezen 
Ovarian torsion is one of the gynecological emergencies that affect ovarian tissue integrity and fertility. In this study, we aim to investigate the effects of Momordica charantia (MC) on ovarian tissue injur...
关键词:FOLLICLES Histology Ischemia Momordica charantia OVARY REPERFUSION 
Shengmai injection attenuates ischemia-reperfusion-induced autophagy correlating to modulating AMPK, mTOR and JNK pathways
《中国药理学通报》2015年第B11期139-140,共2页
Aim Shengmai injection (SMI) , a Chinese patent medicine deprived from an ancient Chinese herbal compound Shengmai san, which is used extensively for the treatment of cardiovascular and cerebrovascular disease in cl...
关键词:CEREBRAL ISCHEMIA REPERFUSION NEUROPROTECTION signal PATHWAYS 
Effects of Chinese Herbal Medicine Serum on the Apoptosis of Sinoatrial Node Cells Induced by Simulated Ischemia-reperfusion被引量:5
《Journal of Traditional Chinese Medicine》2011年第3期224-227,共4页刘如秀 谭双 李敏 彭杰 汪艳丽 刘志明 
supported by the fund from the State Administration of Traditional Chinese Medicine (No.04-05JP61)
Objective:To study the effect of Chinese herbal medicine Kangxin Fumai Granule(康心复脉颗粒 Granule for heart diseases) serum on the primary cultured sinoatrial node(SAN) cell apoptosis induced by simulated ischemia-r...
关键词:Chinese herbal medicine serum pharmacology ISCHEMIA-REPERFUSION sinoatrial node cell apoptosis 
Metallothionein mediates cardioprotection of isoliquiritigenin against ischemia-reperfusion through JAK2/STAT3 activation被引量:25
《Acta Pharmacologica Sinica》2006年第11期1431-1437,共7页Wei AN Jing YANG Ying AO 
Aim: To examine whether isoliquiritigenin (ISL) can attenuate myocardial ischemiareperfusion (MI/R) injury in rats by inducing metallothionein (MT) through activation of janus kinase 2 (JAK 2)/signal transduc...
关键词:ISOLIQUIRITIGENIN myocardial ischemiareperfusion METALLOTHIONEIN janus kinase STAT3 transcription factors 
Exogenous acid fibroblast growth factor inhibits ischemia-reperfusion-induced damage in intestinal epithelium via regulating P53 and P21WAF-1 expression
《World Journal of Gastroenterology》2005年第44期6981-6987,共7页Wei Chen Xiao-Bing Fu Shi-Li Ge Tong-Zhu Sun Zhi-Yong Sheng 
Supported by the National Natural Science Foundation of China,No. 30400172, 30230370the National Basic Science and Development programme (973 programme, 2005 CB 522603)
AIM: To detect the effect of acid fibroblast growth factor (aFGF) on P53 and P21WAF-1 expression in rat intestine after ischemia-reperfusion (I-R) injury in order to explore the protective mechanisms of aFGF. MET...
关键词:Acid fibroblast growth factor ISCHEMIA REPERFUSION P53 gene P21WAF-1 gene 
Effect of simulated ischemia-reperfusion on I_f in sinoatrial node cells and the intervention of KATP channel opener
《Journal of Medical Colleges of PLA(China)》2004年第6期325-328,共4页宋治远 仝识非 钟理 
Supported by National Natural Science Foundation of China (No.30070314)
Objective: To study the effect of simulated ischemia-reperfusion (I/R) on If of sinoatrial node (SAN) cells and the intervention of KATP channel opener Pinacidil. Methods: The SAN cells of the neonatal rats were detac...
关键词:sinoatrial node ISCHEMIA-REPERFUSION IF KATP channel patch clamp technique 
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