ISCHEMIC

作品数：602被引量：1968H指数：20
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相关机构：首都医科大学北京大学上海交通大学附属第六人民医院青岛大学更多>>
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Schisandrin B Protects against Ischemic Brain Damage by Regulating PI3K/AKT Signaling in Rats被引量：2
《Chinese Journal of Integrative Medicine》2023年第10期885-894,共10页HONG Quan-long DING Yi-hang CHEN Jing-yi SHI Song-sheng LIANG Ri-sheng TU Xian-kun 
the Natural Science Foundation of Fujian Province of China(No.2022J01245);the Quanzhou City Science&Technology Program of China(No.2020N020s);the Excellent Young Scholars Cultivation Project of Fujian Medical University Union Hospital(No.2022XH040)。
Objective To explore the effect and mechanism of schisandrin B(Sch B)in the treatment of cerebral ischemia in rats.Methods The cerebral ischemia models were induced by middle cerebral artery occlusion(MCAO)and reperfu...
关键词：cerebral ischemia inflammation NEUROPROTECTION PI3K/AKT signaling schisandrin B Chinese medicine 
Neuroprotective effects of ischemic adaptation on cognitive dysfunction in mice with cerebral ischemia-reperfusion injury
《Journal of Translational Neuroscience》2023年第3期20-27,共8页Yongxin Ma Meng Zhang Meng Geng Wenjing Zhou Xiuhua Bai Yaoming Xu 
Natural Science Foundation of Inner Mongolia Autonomous Region(2021MS08169).
Objective: To observe the effects of remote ischemia on cognitive function and neuronal pathological damage in rats with cognitive impairment induced by bilateral common carotid artery occlusion(BCAO).Methods:Male SD ...
关键词：remote ischemic conditioning cere-bral ischemia-reperfusion cognitive impairment hippo-campal changes NEUROPROTECTION 
Homer signaling pathways as effective therapeutic targets for ischemic and traumatic brain injuries and retinal lesions被引量：4
《Neural Regeneration Research》2022年第7期1454-1461,共8页Xiu-Quan Wu Ning Su Zhou Fei Fei Fei 
supported by the National Natural Science Foundation of China,Nos.81600738(to FF),81771239(to ZF),81801300(to NS)。
Ischemic and traumatic insults to the central nervous system account for most serious acute and fatal brain injuries and are usually characterized by primary and secondary damage.Secondary damage presents the greatest...
关键词：brain injury calcium signaling cerebral ischemia dendritic spine glutamate receptor Homer scaffolding protein neuron NEUROPROTECTION retinal ganglion cell review traumatic brain injury 
Glycogen synthase kinase-3β inhibitor SB216763 promotes DNA repair in ischemic retinal neurons被引量：3
《Neural Regeneration Research》2021年第2期394-400,共7页
the National Natural Science Foundation of China,Nos.81670848(to JZhuang)and 81900850(to YY)。
Glycogen synthase kinase-3β(GSK-3β) has been shown to attenuate DNA damage in nerve cells, thereby enhancing neuronal survival under pathological conditions;however, the underlying mechanism remains unclear. An in v...
关键词：factor GSK-3Β in vitro injury ligase IV NEUROPROTECTION optic nerve PATHWAYS protein repair 
An enriched environment increases the expression of fibronectin type Ⅲ domain-containing protein 5 and brain-derived neurotrophic factor in the cerebral cortex of the ischemic mouse brain被引量：12
《Neural Regeneration Research》2020年第9期1671-1677,共7页Ke-Wei Yu Chuan-Jie Wang Yi Wu Yu-Yang Wang Nian-Hong Wang Shen-Yi Kuang Gang Liu Hong-Yu Xie Cong-Yu Jiang Jun-Fa Wu 
supported by the National Natural Science Foundation of China,Nos.81601961(to KWY),81672242(to YW);the Key Construction Projects of Shanghai Health and Family Planning on Weak Discipline,China,No.2015ZB0401(to YW)
Many studies have shown that fibronectin type III domain-containing protein 5(FDNC5) and brain-derived neurotrophic factor(BDNF) play vital roles in plasticity after brain injury. An enriched environment refers to an ...
关键词：beam-walking test brain-derived neurotrophic factor cerebral ischemia correlation analysis enriched environment fibronectin typeⅢdomain-containing protein 5 Morris water maze task neural plasticity NEUROPROTECTION permanent middle cerebral artery occlusion 
Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review被引量：13
《Neural Regeneration Research》2020年第5期773-782,共10页Yazdan Naderi Yunes Panahi George E. Barreto Amirhosein Sahebkar 
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models.By searching in the databases of PubMed,ScienceDirect,and Scopus,and considering the inclusion and exclusion criteria of...
关键词：ISCHEMIC STROKE MINOCYCLINE NEURONAL regeneration NEUROPROTECTION STROKE 
Nanotechnology-based therapeutics: new hope for ischemic cerebral stroke intervention
《Journal of Translational Neuroscience》2020年第1期8-17,共10页Sihan Wang Qiming Gao Fuyao Xiao Yuming Zhao 
Ischemic cerebral stroke is a leading cause of death and disability globally.At present,thrombolytics,such as recombinant tissue-type plasminogen activator,are the only effective treatment for acute stroke.However,usa...
关键词：ischemic cerebral stroke blood-brain barrier(BBB) nanoparticles drug delivery NEUROPROTECTION 
Therapeutic potential of natural compounds from Chinese medicine in acute and subacute phases of ischemic stroke被引量：23
《Neural Regeneration Research》2020年第3期416-424,共9页Bei Zhang Kathryn ESaatman Lei Chen 
supported by AHA Award 14SDG20480186(to LC);Kentucky Spinal Cord&Head Injury Research Trust Grant 14-12A(to KES);Startup Funds from Shaanxi University of Chinese Medicine to Young Investigators(1410170078)(to BZ)
Stroke is one of the leading causes of death and disability in adults worldwide,resulting in huge social and financial burdens.Extracts from herbs,especially those used in Chinese medicine,have emerged as new pharmace...
关键词：cell death HERBAL compound immune response ISCHEMIC stroke therapy NEUROPLASTICITY NEUROPROTECTION oxidative damage traditional Chinese medicine 
MicroRNA-365 Knockdown Prevents Ischemic Neuronal Injury by Activating Oxidation Resistance 1-Mediated Antioxidant Signals被引量：4
《Neuroscience Bulletin》2019年第5期815-825,共11页Jia-Lin Mo Zhi-Guang Pan Xiao Chen Yu Lei Ling-Ling Lv Cheng Qian Feng-Yan Sun 
supported by grants from the National Natural Science Foundation of China (81030020, 81571197, and 81771268);the National Education Program of China (J0730860)
Micro RNA-365(mi R-365) is upregulated in the ischemic brain and is involved in oxidative damage in the diabetic rat. However, it is unclear whether mi R-365 regulates oxidative stress(OS)-mediated neuronal damage aft...
关键词：MICRORNA ISCHEMIC stroke NEURONAL damage Oxidative stress NEUROPROTECTION 
Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor被引量：5
《Neural Regeneration Research》2017年第9期1381-1389,共9页Carolina Castillo Hernández Carlos Felipe Burgos Angela Hidalgo Gajardo Tiare Silva-Grecchi Javiera Gavilan Jorge Roberto Toledo Jorge Fuentealba 
supported by the Innova Proyect,No.13IDL218688;Fondecyt Proyect,No.1130747,1161078;PhD CONICYT Grant,No.21130386
Erythropoietin （Epo） is a fundamental hormone in the regulation of hematopoiesis, and other secondary roles mediated by the binding of the hormone to its specific receptor （EpoR）, which leads to an activation of k...
关键词：ERYTHROPOIETIN erythropoietin receptor NEUROPROTECTION ANTI-APOPTOSIS Alzheimer＇s disease 
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