supported by the Sun Yat-sen University Clinical Research 5010 Program(2018012).
Retinitis pigmentosa(RP)is characterized by progressive photoreceptor cells death accelerated by the proliferation and activation of microglia pathologically.No consensus exists on the treatment.Minocycline is recogni...
Supported by National Natural Science Foundation of China,No.82170562;Beijing Natural Science Foundation,No.7232199;Capital’s Funds for Health Improvement and Research,No.2022-2-4093;Youth Incubation Fund of Peking University Third Hospital,No.BYSYFY2021003;Key Laboratory for Helicobacter pylori Infection and Upper Gastrointestinal Diseases in Beijing,No.BZ0371.
BACKGROUND Difficulty in obtaining tetracycline,increased adverse reactions,and relatively complicated medication methods have limited the clinical application of the classic bismuth quadruple therapy.Therefore,the se...
BACKGROUND Morbihan disease is a rare skin condition with diagnostic and therapeutic challenges.Facial nonpitting erythematous edema is usually considered to be a characteristic manifestation and diagnostic clue for t...
the National Natural Science Foundation of China(grants 32025017,32121002,81971264,and 32271176);CAS Project for Young Scientists in Basic Research(YSBR-013);Natural Science Foundation of Anhui Province(KJ2020A0138).
funding provided by Faculty seed grant (FSG) from NJIT, Newark, USA " (NC and Venkatesan Perumal).
Blast injuries are common among the military service members and veterans.One of the devastating effects of blast wave induced TBI is either temporary or permanent hearing loss.Treating hearing loss using minocycline ...
funded by an award “Minocycline plus N-acetylcysteine improves brain structure and function after experimental brain injury with clinically useful time window”(NS108190) to PJB
Traumatic brain injury has a complex pathophysiology that produces both rapid and delayed brain damage. Rapid damage initiates immediately after injury. Treatment of traumatic brain injury is typically delayed many ho...
supported by the research grants from the National Natural Science Foundation of China(81625008 and 31970952);the National Key Research and Development Program of China(2020YFA0804500,2020YFA0804502)。
Objective To examine the neuroanatomical substrates underlying the effects of minocycline in alleviating lipopolysaccharide(LPS)-induced neuroinflammation.Methods Forty C57BL/6 male mice were randomly and equally divi...
supported by the National Natural Science Foundation of China(No.81673376);the National Natural Science Foundation of Chongqing(cstc2015jcyj BX0100);the project for innovative Research Group at Higher Educational Institutions in Chongqing(CXQT20006)。
Targeted delivery of therapeutics for spinal cord injury(SCI)has been a long-term challenge due to the complexity of the pathological procession.Macrophage,as an immune cell,can selectively accumulate at the trauma si...
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models.By searching in the databases of PubMed,ScienceDirect,and Scopus,and considering the inclusion and exclusion criteria of...
Medical and health science and technology innovation project of Sanya city(No.YW1323).
Objective: To study the efficacy of minocycline hydrochloride sustained-release agent combined with Vitapex in the treatment of invasive periodontitis. Method 80 patients with erosive periodontitis were randomly divid...