LIGAND

作品数：1089被引量：2088H指数：16
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相关机构：河北师范大学第二军医大学苏州大学复旦大学更多>>
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C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury
《Neural Regeneration Research》2025年第8期2231-2244,共14页Xiangzi Wang Xiaofei Niu Yingkai Wang Yang Liu Cheng Yang Xuyi Chen Zhongquan Qi 
supported by the National Natural Science Foundation of China(Key Program),No.11932013;the National Natural Science Foundation of China(General Program),No.82272255;Armed Police Force High-Level Science and Technology Personnel Project;The Armed Police Force Focuses on Supporting Scientific and Technological Innovation Teams;Key Project of Tianjin Science and Technology Plan,No.20JCZDJC00570(all to XC)。
Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory damage.The expression of the C-C motif chemokine ligand...
关键词：apoptosis C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway C-C motif chemokine receptor 2 antagonists chemokine ligand 2 chemokine receptor 2 inflammation macrophage microglia spinal cord injury therapeutic method 
Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer:A meta-analysis
《World Journal of Clinical Oncology》2025年第4期280-290,共11页Hong-Chang Yang Cheng-Feng Fu Li-Jun Qiao Gen-He Long Li-Fen Yang Biao Yao 
BACKGROUND Gastric cancer(GC)is one of the most common malignancies worldwide,and Helicobacter pylori(HP)infection is a well-established risk factor for its development.Programmed death-ligand 1(PD-L1)expression is a ...
关键词：Helicobacter pylori Gastric cancer Programmed cell death protein 1/programmed death-ligand 1 Immune checkpoint blockade therapy PATHOGENESIS 
Air-Sintering of Dual-Ligand Capped Copper Nanoparticles for High-Temperature Interconnect Applications
《cMat》2025年第1期26-38,共13页Yu-Ji Zheng Jun-Jie Yuan Qing-Hua Li Zhe-Fei Sun Heng-Hui Wang Xiang Wu Ti-Xun Li Zi-Yu Zhou Shi-Yu Xia Jin-Tang Li Hui-Jun Cao Wen-Zhi Cai Jonghwan Suhr Zhi-Hao Zhang 
supported by the Natural Science Foundation of Fujian Province(No.2022J01044);the Digital Twin and Intelligent Transportation Maintenance Engineering Research Centre of Genting Applied Technology R&D Platform at Xiamen City University。
Copper nanoparticles(CuNPs)have promising applications in energy storage,sensing,and chip manufacturing because of their excellent properties and low cost.However,oxidation limits their sinterability and performance a...
关键词：air sintering Cu nanoparticle flexible sensor high-temperature antioxidant 
In situ synthesis,crystal structure,and magnetic characterization of a trinuclear copper complex based on a multi-substituted imidazo[1,5-a]pyrazine scaffold
《无机化学学报》2025年第3期597-604,共8页WANG Zhaodong 
A trinuclear copper complex [Cu_(3)(L2)_(2)(SO_(4))_(2)(H_(2)O)_(7)]·8H_(2)O(1)(HL2=1-hydroxy-3-(pyrazin-2-yl)-N-(pyrazin-2-ylmethyl)imidazo[1,5-a]pyrazine-8-carboxamide) with a multi-substituted imidazo[1,5-a]pyrazi...
关键词：amide ligand copper complex single crystal structure C-N coupling magnetic characterization 
Surface ligand-promoted heterogeneous CO_(2) catalysis
《Science China Chemistry》2025年第2期444-457,共14页Zhe Lu Lu Wang 
supported by the National Key R&D Program of China(2021YFF0502000);the National Natural Science Foundation of China(52102311);the Shenzhen Natural Science Foundation 2022,the Shenzhen Key Laboratory of Eco-materials and Renewable Energy(ZDSYS20200922160400001);the Provincial Talent Plan(2023TB0006);the University Development Fund(UDF01001721).
Heterogeneous CO_(2) catalysis towards the synthesis of high-value products provides a potent pathway for achieving carbon neutrality.The distinctive attributes of surface ligands allow for highly effective tuning of ...
关键词：heterogeneous catalysis CO_(2) conversion surface ligands 
Ligand-mediated reactivity in CO oxidation of yttrium-nickel monoxide carbonyl complexes
《Chinese Chemical Letters》2025年第2期151-155,共5页Jumei Zhang Ziheng Zhang Gang Li Hongjin Qiao Hua Xie Ling Jiang 
supported by the Natural Science Foundation of Shandong Province(No.ZR2021QB215);the National Natural Science Foundation of China(Nos.22273101,22125303,92061203,21327901,and 22288201);Dalian Institute of Chemical Physics(No.DICP I202437);the Talent Induction Program for Youth Innovation Teams in Colleges and Universities of Shandong Province(No.2022-2024);the Talent Introduction Research Start-up Funds of Ludong University(No.20212026)。
A series of heteronuclear yttrium-nickel monoxide carbonyl complexes YNiO(CO)_(n)^(-)(n=1-5)were generated in a pulsed-laser vaporization source and characterized by mass-selected photoelectron velocity-map spectrosco...
关键词：Heteronuclear cluster CO oxidation Electron donor Quantum chemical calculation Photoelectron velocity-map imaging spectroscopy 
Auxiliary ligand-induced assembly of atomically precise silver clusters
《Science China Chemistry》2025年第2期580-589,共10页Yeqin Feng Xuemeng Jing Fangyu Fu Mengyun Zhao Manzhou Chi Hongjin Lv Guo-Yu Yang 
supported by the National Natural Science Foundation of China(22471017,21831001,22001016);the China Postdoctoral Science Foundation(2020TQ0038);the Recruitment Program of Global Experts(Young Talents);the Beijing Institute of Technology(BIT)Excellent Young Scholars Research Fund.
Establishing the correlation between inter-cluster assembly and auxiliary ligands at the atomic level is crucial for the development of metal cluster science.In this work,we report the successful preparation and chara...
关键词：silver(I)clusters auxiliary ligand effect silver cluster synthesis LUMINESCENCE 
RADICAL:a rationally designed ion channel activated by ligand for chemogenetics
《Protein & Cell》2025年第2期136-142,共7页Heng Zhang Zhiwei Zheng Xiaoying Chen Lizhen Xu Chen Guo Jiawei Wang Yihui Cui Fan Yang 
supported by funding from the National Natural Science Foundation of China(32122040 and 31971040 to F.Y.;32071017 and 31922031 to Y.C.);Zhejiang Provincial Natural Science Foundation of China(LR20C050002 to F.Y.);China Postdoctoral Program for Innovative Talents(BX20230323 to H.Z.);China Postdoctoral Science Foundation(2024M752858 to H.Z.);The Fundamental Research Funds for the Central Universities(226-2022-00227 to F.Y.;226-2022-00149 to Y.C.);Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019001 to Y.C.);The Fundamental Research Funds for the Central Universities(226-2022-00227 to F.Y.)。
Dear Editor,Manipulating neuronal activities by exogenous means is always much desired in the field of neuroscience and beyond.Though many optogenetics and chemogenetics tools,such as channelrhodopsins and DREADDs(Arm...
关键词：RATIONAL CHANNEL LIMITATIONS 
Ligand engineering of Co-MOF-74 with hexaaminotriphenylene for enhanced oxygen reduction reaction in zinc-air batteries
《Nano Research》2025年第2期290-297,共8页Wei Liu Yu Liang Mengtian Huo Nan Ma Kaichi Qin Jinfa Chang Zihao Xing 
This work was supported by National Natural Science Foundation of China(Nos.22202037,22472023 and 22102105);the Fundamental Research Funds for the Central Universities(Nos.2412024QD014 and 2412023QD019).
Zinc-air batteries hold great promise as a next-generation efficient and environmentally friendly energy technology.However,the sluggish kinetics of the oxygen reduction reaction(ORR)process pose a significant challen...
关键词：molecular catalysts oxygen reduction reaction zinc-air battery coordination environment metal-organic framework 
Tumor derived cell-free nucleic acid upregulates programmed death-ligand 1 expression in neutrophil via intracellular Toll-like receptor signaling
《Cancer Communications》2025年第1期4-8,共5页Suguru Saito Duo-Yao Cao Tomohiro Shibata Yan Liu Aoi Otagiri-Hoshi Xiaojiang Cui Kenneth E.Bernstein 
supported by the National Institutes of Health grants(R01AI164519,2R01CA151610,R21CA280458);American Heart Association’s Career Development award(23CDA1052548);U.S.Department of Defense(W81XWH-18-1-0067)and the Glazer Foundation.
Neutrophils are innate immune cells that function predominantly against pathogens,while recent studies have revealed additional crucial roles in various diseases,including cancers[1–3].For instance,neutrophils expres...
关键词：DEATH diseases programmed 
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