LIGAND

作品数:1097被引量:2104H指数:16
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相关领域:理学医药卫生更多>>
相关作者:韩占刚兰小鹏李卫滨赵丹吴文冰更多>>
相关机构:河北师范大学第二军医大学苏州大学复旦大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金福建省自然科学基金更多>>
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C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury
《Neural Regeneration Research》2025年第8期2231-2244,共14页Xiangzi Wang Xiaofei Niu Yingkai Wang Yang Liu Cheng Yang Xuyi Chen Zhongquan Qi 
supported by the National Natural Science Foundation of China(Key Program),No.11932013;the National Natural Science Foundation of China(General Program),No.82272255;Armed Police Force High-Level Science and Technology Personnel Project;The Armed Police Force Focuses on Supporting Scientific and Technological Innovation Teams;Key Project of Tianjin Science and Technology Plan,No.20JCZDJC00570(all to XC)。
Spinal cord injury involves non-reversible damage to the central nervous system that is characterized by limited regenerative capacity and secondary inflammatory damage.The expression of the C-C motif chemokine ligand...
关键词:apoptosis C-C motif chemokine ligand 2/C-C motif chemokine receptor 2 pathway C-C motif chemokine receptor 2 antagonists chemokine ligand 2 chemokine receptor 2 inflammation macrophage microglia spinal cord injury therapeutic method 
Cytoplasmic and nuclear programmed death ligand 1 expression in peritumoral stromal cells in breast cancer:Prognostic and predictive value
《World Journal of Experimental Medicine》2025年第2期150-170,共21页Evgeniya Yu Zubareva Marina A Senchukova Natalia V Saidler 
Supported by Russian Science Foundation,No.23-25-00183.
BACKGROUND Breast cancer(BC)continues to occupy a leading position in terms of morbidity and mortality from malignant neoplasms among the female population.One of the promising markers associated with BC progression i...
关键词:Breast cancer Programmed death-ligand 1 Regional metastasis Tumor stroma 
15.13%Sr-doped CsPbI_(3) quantum dots with near-unity quantum yield via surface ligand compensation
《Nano Research》2025年第4期534-543,共10页Yi Peng Wanzhong Gu Yuhui Dong Yucong Ji Danni Yan Ziyun Lin Li Zhang Yousheng Zou Haibo Zeng 
the National Natural Science Foundation of China(Nos.62374089,61904081,and 51672132);the Natural Science Foundation of Jiangsu Province(No.BK20190449);the Postdoctoral Research Funding Program of Jiangsu Province(No.2020Z144);the Fundamental Research Funds for the Central Universities(No.30923010928).
Sr-doping of perovskite quantum dots(QDs)is a promising strategy to reduce Pb content and improve optical performance and stability.However,excessive Sr introduces new defects that degrade photoluminescence quantum yi...
关键词:CsPbI_(3)quantum dots Sr-doping ligand compensation photoluminescence quantum yield environmental stability 
Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer:A meta-analysis
《World Journal of Clinical Oncology》2025年第4期280-290,共11页Hong-Chang Yang Cheng-Feng Fu Li-Jun Qiao Gen-He Long Li-Fen Yang Biao Yao 
BACKGROUND Gastric cancer(GC)is one of the most common malignancies worldwide,and Helicobacter pylori(HP)infection is a well-established risk factor for its development.Programmed death-ligand 1(PD-L1)expression is a ...
关键词:Helicobacter pylori Gastric cancer Programmed cell death protein 1/programmed death-ligand 1 Immune checkpoint blockade therapy PATHOGENESIS 
Dual-ligand engineering over Au-based catalyst for efficient acetylene hydrochlorination
《Chinese Chemical Letters》2025年第3期422-426,共5页Yongsheng Xu Lisha Yao Jian Li Yanzhao Dong Dongyang Xie Miaomiao Zhang Feng Li Yunsheng Dai Jinli Zhang Haiyang Zhang 
supported by the National Natural Science Foundation of China(No.22068031);Yunnan Precious Metals Laboratory Science and Technology Project(No.YPML-2022050237);Major Science and Technology Project of Yunnan Precious Metal Laboratory(No.YPML-2023050202);the Science and Technology Project of Xinjiang Bingtuan supported by Central Government(No.2022BC001);Tianshan Talents Training Program of Xinjiang Science and Technology Innovation Team(No.2022TSYCTD0021);the Start-Up Foundation for Young Scientists of Shihezi University(No.RCZK202419);the Project of Achievement Transformation and Technology Extension of Shihezi University(No.CGZH202302)。
Introducing ligand into the surface of gold(Au)-based catalyst has been recognized as an efficient strategy to enhance the performance of catalyst in acetylene hydrochlorination reaction.However,due to the multifactor...
关键词:Acetylene hydrochlorination Gold-based catalyst Dual-ligand engineering Catalytic performance enhancement 
Air-Sintering of Dual-Ligand Capped Copper Nanoparticles for High-Temperature Interconnect Applications
《cMat》2025年第1期26-38,共13页Yu-Ji Zheng Jun-Jie Yuan Qing-Hua Li Zhe-Fei Sun Heng-Hui Wang Xiang Wu Ti-Xun Li Zi-Yu Zhou Shi-Yu Xia Jin-Tang Li Hui-Jun Cao Wen-Zhi Cai Jonghwan Suhr Zhi-Hao Zhang 
supported by the Natural Science Foundation of Fujian Province(No.2022J01044);the Digital Twin and Intelligent Transportation Maintenance Engineering Research Centre of Genting Applied Technology R&D Platform at Xiamen City University。
Copper nanoparticles(CuNPs)have promising applications in energy storage,sensing,and chip manufacturing because of their excellent properties and low cost.However,oxidation limits their sinterability and performance a...
关键词:air sintering Cu nanoparticle flexible sensor high-temperature antioxidant 
In situ synthesis,crystal structure,and magnetic characterization of a trinuclear copper complex based on a multi-substituted imidazo[1,5-a]pyrazine scaffold
《无机化学学报》2025年第3期597-604,共8页WANG Zhaodong 
A trinuclear copper complex [Cu_(3)(L2)_(2)(SO_(4))_(2)(H_(2)O)_(7)]·8H_(2)O(1)(HL2=1-hydroxy-3-(pyrazin-2-yl)-N-(pyrazin-2-ylmethyl)imidazo[1,5-a]pyrazine-8-carboxamide) with a multi-substituted imidazo[1,5-a]pyrazi...
关键词:amide ligand copper complex single crystal structure C-N coupling magnetic characterization 
CCL2-CCR2 axis in cardiovascular disease:research advances and challenges
《Science Bulletin》2025年第6期820-824,共5页Yang Yang Jiayan Li Jiayou Tang Bo Wang Jing Wang Xuezeng Xu Wangrui Lei Ying Cheng Liwen Liu 
supported by the National Natural Science Foundation of China(82270526,82070422,82200330,82071932,82371974,and 82272009);Key Medical Research Projects in Xi’an City(24YXYJ0010);Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Project(TZKN-CXRC-06);Research Plan Project of Shaanxi Institute of Basic Science(22JHQ053);Qinchuangyuan Traditional Chinese Medicine Innovation Research and Development Transformation Project(2022-QCYZH-036).
C-C motif chemokine ligand 2(CCL2)is a member of the chemokine family and is also known as monocyte chemoattractant protein-1.It is a crucial factor for regulating the migration and infiltration of various immune cell...
关键词:monocyte chemoattractant protein chemokine family cardiovascular disease CCL immune cells migration infiltration c chemokine ligand MONOCYTES 
Surface ligand-promoted heterogeneous CO_(2) catalysis
《Science China Chemistry》2025年第2期444-457,共14页Zhe Lu Lu Wang 
supported by the National Key R&D Program of China(2021YFF0502000);the National Natural Science Foundation of China(52102311);the Shenzhen Natural Science Foundation 2022,the Shenzhen Key Laboratory of Eco-materials and Renewable Energy(ZDSYS20200922160400001);the Provincial Talent Plan(2023TB0006);the University Development Fund(UDF01001721).
Heterogeneous CO_(2) catalysis towards the synthesis of high-value products provides a potent pathway for achieving carbon neutrality.The distinctive attributes of surface ligands allow for highly effective tuning of ...
关键词:heterogeneous catalysis CO_(2) conversion surface ligands 
Ligand-mediated reactivity in CO oxidation of yttrium-nickel monoxide carbonyl complexes
《Chinese Chemical Letters》2025年第2期151-155,共5页Jumei Zhang Ziheng Zhang Gang Li Hongjin Qiao Hua Xie Ling Jiang 
supported by the Natural Science Foundation of Shandong Province(No.ZR2021QB215);the National Natural Science Foundation of China(Nos.22273101,22125303,92061203,21327901,and 22288201);Dalian Institute of Chemical Physics(No.DICP I202437);the Talent Induction Program for Youth Innovation Teams in Colleges and Universities of Shandong Province(No.2022-2024);the Talent Introduction Research Start-up Funds of Ludong University(No.20212026)。
A series of heteronuclear yttrium-nickel monoxide carbonyl complexes YNiO(CO)_(n)^(-)(n=1-5)were generated in a pulsed-laser vaporization source and characterized by mass-selected photoelectron velocity-map spectrosco...
关键词:Heteronuclear cluster CO oxidation Electron donor Quantum chemical calculation Photoelectron velocity-map imaging spectroscopy 
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