LIQUID_CHROMATOGRAPHY

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Recent Advances in Mass Spectrometry-based Separation of Native Proteins
《Chemical Research in Chinese Universities》2025年第2期211-221,共11页JIA Fanyu JIANG Ting XU Wei 
supported by the Beijing Institute of Technology Research Fund Program for Young Scholars,China(No.XSQD-6120230051).
Native proteins refer to proteins that exist in their natural state, have a correctly folded three-dimensional structure, and have biological functions. Characterization of protein higher-order structure and protein-p...
关键词：Native mass spectrometry Protein separation Liquid chromatography Capillary electrophoresis Protein structure Protein-protein interaction Free-flow electrophoresis 
Homozygous phytosterolemia and a literature review:A case report
《World Journal of Clinical Cases》2025年第10期46-52,共7页Chun-Xin Jiang Guang Yang Lian-Ping Shi Peng-Yu Su 
Supported by Natural Science Foundation of Heibei Province,No.H2020209160。
BACKGROUND Phytosterolemia,also known as sitosterolemia,is a rare autosomal recessive disease characterized by elevated plasma plant sterol levels and xanthomata,which is easily misdiagnosed as familial hypercholester...
关键词：HYPERCHOLESTEROLEMIA CHOLESTEROL Low-density lipoprotein Phytosterolemia Liquid chromatography ABCG5/ABCG8 Sitosterolemia 
Reprogramming the Metabolome of Centella asiatica (L.) Urban Callus: Profiling of Newly Synthesized Cryptic Anthocyanins Triggered by LED Light Exposure
《Phyton-International Journal of Experimental Botany》2025年第4期1269-1286,共18页Claude Y.Hamany Djande Paul A.Steenkamp Ian A.Dubery 
Centella asiatica L.,a medicinal herb,has attracted substantial interest in research as well as commercial domains due to its bioactive compounds which include the pentacyclic triterpenoid centellosides,and in additio...
关键词：Anthocyanins CALLUS Centella asiatica CRYPTIC FLAVONOIDS liquid chromatography mass spectrometry REPROGRAMMING 
An ionic liquid assisted hydrogel functionalized silica stationary phase for mixed-mode liquid chromatography
《Chinese Chemical Letters》2025年第1期491-495,共5页Tong Zhang Xiaojing Liang Licheng Wang Shuai Wang Xiaoxiao Liu Yong Guo 
Innovation Groups of Basic Research in Gansu Province(No.23JRRA570)。
An ionic liquid assisted hydrogel modified silica was synthesized using a one-pot polymerization and physical coating technique and subsequently applied to mixed-mode liquid chromatography.Analytical techniques,includ...
关键词：Ionic liquid HYDROGEL Functionalized silica Synergistic effect Stationary phase 
Comprehensive Analysis of Detection Methods for Over-the-counter Codeine:A Systematic Review
《Journal of Forensic Science and Medicine》2024年第4期309-327,共19页Anagha Ravindran Tina Sharma Mahipal Singh Sankhla 
Concerns have been raised about how readily available over-the-counter(OTC)codeine formulations may be contributing to the expanding opioid epidemic.Focusing on the analytical methods used to find and measure codeine ...
关键词：CODEINE drug of abuse forensic chemistry forensic science gas chromatography‑mass spectrometry high‑pressure liquid chromatography over‑the‑counter drug papaver somniferum 
Chemical isotope labeling-assisted liquid chromatography-mass spectrometry enables sensitive and accurate determination of dipeptides and tripeptides in complex biological samples
《Chinese Chemical Letters》2024年第11期284-289,共6页Feng-Qing Huang Yu Wang Ji-Wen Wang Dai Yang Shi-Lei Wang Yuan-Ming Fan Raphael N.Alolga Lian-Wen Qi 
financially supported in part by the National Natural Science Fund of China for Distinguished Young Scholars(No.81825023);National Natural Science Foundation of China(No.82003979);Natural Science Foundation of Shanghai(No.23ZR1459100)。
Small peptides have attracted increasing attention for their unique features and diverse biological functions.Achieving rapid separation and accurate quantification,however,remains a challenge because of their low abu...
关键词：Di/tripeptides Chemical derivatization Isotope labeling Liquid chromatography tandem mass SPECTROMETRY Biliary tract cancer 
High throughput and rapid isolation of extracellular vesicles and exosomes with purity using size exclusion liquid chromatography
《Bioactive Materials》2024年第10期683-695,共13页Kshipra S.Kapoor Kristen Harris Kent A.Arian Lihua Ma Beatriz Schueng Zancanela Kaira A.Church Kathleen M.McAndrews Raghu Kalluri 
supported by NCI R35CA263815.KAC is supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Numbers TL1TR003169 and UL1TR003167;The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health;We are grateful to Dr.Wenhua Guo for training KSK on cryogenic electron microscopy and Michelle Kirtley for assistance with serum samples.LM is thankful to the Shared Equipment Authority at Rice University for the support.Graphical figures in this work were created using BioRender.
Extracellular vesicles(EVs)have emerged as potential biomarkers for diagnosing a range of diseases without invasive procedures.Extracellular vesicles also offer advantages compared to synthetic vesicles for delivery o...
关键词：Extracellular vesicles Size exclusion-fast performance liquid CHROMATOGRAPHY Isolation methods 
Cannabinoid Modulation of Monoamine Levels in Mouse Brain:Unveiling Neurochemical Dynamics through an Innovative High‑performance Liquid Chromatography‑Fluorescence Detection Bioanalysis
《Journal of Analysis and Testing》2024年第3期300-314,共15页Fonseca Carla Cunha Susana Ferreira Ricardo Lapo Pais Mariana Goncalves Joana Camins Antoni Ettcheto Miren Barbosa Rui Fortuna Ana 
supported by funds from Fundacao para a Ciencia e a Tecnologia(FCT),Portugal,European Union,MCTES,and Fundo Social Europeu(FSE)in the scope of the Centro 2020 Regional Operational Programme(Carla’s PhD research grant 2021.06135;BD and Mariana’s PhD research grant 2020.6582.BD);supported by FCT Exploratory Project 2022.01066.PTDC,COMPETE and FEDER funds,FCT,Portugal.Figures 1 and 2 were created with BioRender.com.
Homeostasis of monoaminergic pathways is compromised in aging and neurodegenerative/neurological diseases such as Alzheimer’s disease and depression.On the other hand,their modulation has also been linked to the mech...
关键词：NEUROTRANSMITTER HPLC Mice Brain Prefrontal cortex CANNABINOID 
Integrated Phytochemical Analysis Based on Ultra-high-performance Liquid Chromatography-mass Spectrometry and Network Pharmacology Approaches to Explore Qingre Formula
《World Journal of Traditional Chinese Medicine》2024年第3期370-382,共13页Wen-Ya Gao Yan Zhang Li-Juan Zhou Min Li Tao Li Chang Gao Shuang-Rong Gao Nan Si Xiao-Lu Wei Bao-Lin Bian Hong-Jie Wang Yan-Yan Zhou Hai-Yu Zhao 
financially by the Scientific and technological innovation project of China Academy of Chinese Medical Sciences (No. CI2021A01606, CI2021A04507, CI2021A04510, Cl2021A04502, CI2021A04509);National Administration of Traditional Chinese Medicine Young Qihuang Scholar Project,China;Qianjiang Distinguished Expert Project of Hangzhou (2020), China
Objective: This study aims to elucidate and quantify the composition of Jiangtang Qingre formula(JQF), delineate the absorbed components in the bloodstream, predict the major biologically active components, and identi...
关键词：Diabetes mellitus Jiangtang Qingre formula network pharmacology ultra‑high‑performance liquid chromatography‑LTQ‑Orbitrap mass spectrometry ultra‑high‑performance liquid chromatography‑triple-quadrupole mass spectrometry 
Uncovering Chemical Interactions between Danshen and Danggui Using Liquid Chromatography–Mass Spectrometry and Network Pharmacology-Based Research on Stroke
《World Journal of Traditional Chinese Medicine》2024年第2期230-243,共14页Han-Qing Pang Jia-Xiu Guo Xiao-Yu Shang Jian Wang Hui Liu Jing Tian Lu Zhang Jian-Bin Wang Wei Shi Bing-Chun Yan Liang Liu 
funded by the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Guangxi Normal University) (CMEMR2022-B11);National Natural Science Foundation of China (822044593);Natural Science Foundation of Jiangsu Higher Education Institutions of China (22KJB360018)。
Objective: The objective of this study was to decipher chemical interactions between Danshen and Danggui using liquid chromatography–mass spectrometry(LC-MS) and explore the mechanisms of Danshen–Danggui against str...
关键词：Chemical interactions Danggui DANSHEN liquid chromatography–mass spectrometry network pharmacology 
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