The integrated computational materials engineering(ICME)has achieved great success in accelerating the rational design and deployment of new materials.It is a new route of designing new materials and processes and hig...
Intellectual disability is a broad-spectrum neurodevelopmental disorder characterized by marked impairment of intelligence and adaptive function.Impaired GABA neurotransmission is associated with mental disorders such...
We thank Dr.Su-Chun Zhang(Waisman Center and WiCell Research Institute at the University of Wisconsin)for kindly providing the AAVS1-TALEN plasmids and crispr-cas9 plasmids.This study was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA16010306);the National Natural Science Foundation of China Grants(Grant Nos.81922022,91849117,and 81471301);the National Key Research and Development Program of China(2019YFA0802703 and 2016YFC1306703);the Jiangsu Outstanding Young Investigator Program(BK20160044);the Jiangsu Province's Innovation Program,Postgraduate Research and Practice Innovation Program of Jiangsu Province.
Dear Editor,GABAergic interneurons(GIs)play an essential inhibitory role in regulating neural circuitry and neurological activities.Approximately 54%GABAergic interneuron population originated from medial ganglionic e...
supported by a Natural Sciences and Engineering Research Council of Canada(NSERC)Grant(1455843);a NSERC Canadian Graduate Scholarship(CGS-D).
Introduction Hematopoietic stem and progenitor cells(HSPC)are responsible for the reconstitution of blood cells and thought to contribute to peripheral tissue repair.Following acute exercise in young adults,HSPC are m...