MICRONEEDLES

作品数：81被引量：205H指数：9
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相关机构：安徽医科大学更多>>
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  • 期刊=Asian Journal of Pharmaceutical Sciencesx
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Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation被引量：1
《Asian Journal of Pharmaceutical Sciences》2023年第1期108-119,共12页Baorui Wang Suohui Zhang Guozhong Yang Zequan Zhou Mengzhen Xing Han Liu Aguo Cheng Yunhua Gao 
by the National Key Research and Development Plan of China[No.2016YFC1000902].
To reduce mucosal damage in the gastrointestinal tract caused by aspirin,we developed a dissolvable polymeric microneedle(MN)patch loaded with aspirin.Biodegradable polymers provide mechanical strength to the MNs.The ...
关键词：ASPIRIN Transdermal drug delivery Polymeric microneedles HYDROLYSIS Antiplatelet aggregation 
pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma被引量：3
《Asian Journal of Pharmaceutical Sciences》2022年第5期679-696,共18页Yanjuan Huang Hualu Lai Jingwen Jiang Xiaoyu Xu Zishan Zeng Lingling Ren Qiuxing Liu Meixu Chen Tao Zhang Xin Ding Chunshun Zhao Shengmiao Cui 
supported by the National Natural Science Foundation of China(Grant number:81973256/H3008);Guangdong Basic and Applied Basic Research Foundation(Grant number:2021A1515010475);the Fundamental Research Funds for the Central Universities(22qntd4505).
Photodynamic therapy(PDT)-mediated oxidation treatment is extremely attractive for skin melanoma ablation,but the strong hydrophobicity and poor tumor selectivity of photosensitizers,as well as the oxygen-consuming pr...
关键词：MELANOMA Dissolving microneedles Chemo-photodynamic therapy Oxidation treatment DIHYDROARTEMISININ Hyaluronic acid 
Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders被引量：1
《Asian Journal of Pharmaceutical Sciences》2022年第3期333-352,共20页Yueting Gu Qiong Bian Yanjun Zhou Qiaoling Huang Jianqing Gao 
The hair follicle is not only a critical penetration route in percutaneous absorption but also has been recognized to be a target for hair follicle-associated disorders,such as androgenetic alopecia(AGA)and acne vulga...
关键词：Follicular drug delivery Androgenetic alopecia Acne vulgaris NANOTECHNOLOGY MICRONEEDLES 
Polymeric microneedle-mediated sustained release systems: Design strategies and promising applications for drug delivery被引量：3
《Asian Journal of Pharmaceutical Sciences》2022年第1期70-86,共17页Li Yang Yao Yang Hongzhong Chen Lin Mei Xiaowei Zeng 
financial support from the National Natural Science Foundation of China (32071342 and 31922042);Guangdong Special Support Program (2019TQ05Y209);the Fundamental Research Funds for the Central Universities (19ykzd31)。
Parenteral sustained release drug formulations, acting as preferable platforms for longterm exposure therapy, have been wildly used in clinical practice. However, most of these delivery systems must be given by hypode...
关键词：Transdermal drug delivery MICRONEEDLES Sustained release Long-term exposure therapy 
Enhanced delivery efficiency and sustained release of biopharmaceuticals by complexation-based gel encapsulated coated microneedles:rhIFNα-1b example被引量：3
《Asian Journal of Pharmaceutical Sciences》2021年第5期612-622,共11页Zequan Zhou Suohui Zhang Guozhong Yang Yunhua Gao 
Coated microneedles(MNs) are widely used for delivering biopharmaceuticals. In this study, a novel gel encapsulated coated MNs(GEC-MNs) was developed. The water-soluble drug coating was encapsulated with sodium algina...
关键词：Coated microneedle Drug delivery system Sustained release Interferon alpha 1b Sodium alginate 
Transdermal delivery of fluorescein isothiocyanate-dextrans using the combination of microneedles and low-frequency sonophoresis被引量：1
《Asian Journal of Pharmaceutical Sciences》2015年第5期415-424,共10页Boonnada Pamornpathomkul Sureewan Duangjit Suvida Laohapatarapant Theerasak Rojanarata Praneet Opanasopit Tanasait Ngawhirunpat 
the Thailand Research Fund through the Basic Research Grant(Grant No.5680016);the Faculty of Pharmacy,Silpakorn University,and Mr.Subhachai Saibour,the factory director and department manager at Bangkok Lab and Cosmetics Co.,Ltd.,for facilities and financial support.
This study aimed to evaluate the patient-friendly methods that are used in the delivery of hydrophilic macromolecules into deep skin layers,in particular,the combination of microneedles patch(MNs patch)and low-frequen...
关键词：MICRONEEDLE SONOPHORESIS Fluorescein isothiocyanate-dextran Transdermal drug delivery 
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