MITOCHONDRIAL_DNA

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MSC-mediated mitochondrial transfer restores mitochondrial DNA and function in neural progenitor cells of Leber’s hereditary optic neuropathy
《Science China(Life Sciences)》2024年第11期2511-2519,共9页Rui Wang Feixiang Bao Manjiao Lu Xiaoyun Jia Jiahui Xiao Yi Wu Qingjiong Zhang Xingguo Liu 
financially supported by the National Key Research and Development Program of China(2022YFE0210100,2023YFE0210100,2022YFA1103800,2019YFA0904500);the National Natural Science Foundation projects of China(32025010,92157202,32241002,92254301,92357302,32261160376,31970709,32070729,32100619,32170747,32322022,32370782,32371007,32300608,32300620);NSFC/RGC Joint Grant Scheme 2022/2023(N_CUHK 428/22);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0480000);the Key Research Program,CAS(ZDBS-ZRKJZ-TLC003);International Cooperation Program,CAS(154144KYSB20200006);CAS Project for Young Scientists in Basic Research(YSBR-075);Guangdong Province Science and Technology Program(2023B0303000023,2023B1111050005,2023A1515030231,2022A1515110493,2023B1212060050,2021A1515012513,2021B1515020096,2022A1515012616,2022A1515110951,2023B1212120009,2024A1515010782,2024B1515040020,2024A1515030120);Guangzhou Science and Technology Program(202102021037,202102020827,202102080066,202206060002,2023A04J0414);Health@InnoHK funding support from the Innovation Technology Commission of the Hong Kong SAR,Basic Research Project of Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences;CAS Youth Innovation Promotion Association(to Y.W and K.C).
Leber’s hereditary optic neuropathy(LHON)is a debilitating mitochondrial disease associated with mutations in mitochondrial DNA(mtDNA).Unfortunately,the available treatment options for LHON patients are limited due t...
关键词：MITOCHONDRIA mitochondrial DNA mitochondrial diseases induced pluripotent stem cells stem cells METABOLISM energy mesenchymal stem cells 
Unravelling the genetic basis for skeletal muscle mitochondrial DNA copy number variations in pigs
《Science China(Life Sciences)》2024年第1期211-214,共4页Jiawen Yang Leilei Cui Yifeng Zhang Ziqi Ling Zhou Zhang Yizhong Huang Junwu Ma Shijun Xiao Bin Yang Lusheng Huang 
This work was supported by the National Key Research and Development Program of China(2021YFF1000601).
Dear Editor,Mitochondria are the center of cellular energy generation and free radical metabolism,with important functions in regulating intracellular calcium levels,cell apoptosis,cell cycle and epigenetic modificati...
关键词：METABOLISM CARDIOVASCULAR DISEASES 
Evidence for the paternal mitochondrial DNA in the crucian carp-like fish lineage with hybrid origin被引量：3
《Science China(Life Sciences)》2020年第1期102-115,共14页Shi Wang Ni Jiao Lu Zhao Meiwen Zhang Pei Zhou Xuexue Huang Fangzhou Hu Conghui Yang Yuqin Shu Wuhui Li Chun Zhang Min Tao Bo Chen Ming Ma Shaojun Liu 
supported by the National Natural Science Foundation of China(31802287,31730098,31430088);the China Postdoctoral Science Foundation(2018M632969);the earmarked fund for China Agriculture Research System(CARS-45);the Key Research and Development Program of Hunan Province(2018NK2072);Hunan Provincial Natural Science and Technology Major Project(2017NK1031);the Cooperative Innovation Center of Engineering and New Products for Developmental Biology of Hunan Province(20134486)
In terms of taxonomic status,common carp(Cyprinus carpio,Cyprininae)and crucian carp(Carassius auratus,Cyprininae)are different species;however,in this study,a newborn homodiploid crucian carp-like fish(2n=100)(2nNCRC...
关键词：HYBRIDIZATION homodiploid common carp blunt snout bream crucian carp mitochondrial genome genetic evolution 
Paternal inheritance of mitochondrial DNA in the sheep (Ovine aries)被引量：1
《Science China(Life Sciences)》2001年第3期321-326,共6页赵兴波 储明星 李宁 吴常信 
the Major State Basic Research Development Program of China and the National Natural Science Foundation of China (Grant No. 39770541).
Paternal inheritance of mitochondria DNA in sheep was discovered by examination of 152 sheep from 38 hybrid families for mtDNA D-loop polymorphisms using PCR-RFLP, amplification of repeated sequence somain, and PCR-SS...
关键词：SHEEP mitochondria DNA paternal inheritance. 
Sequence of mitochondrial DNA cytochrome oxidase II in Cryptopygus nanjiensis and Phylogeny of Apterygota被引量：1
《Science China(Life Sciences)》2000年第6期589-596,共8页邵红光 张亚平 柯欣 岳巧云 尹文英 
The mitochondrial cytochrome oxidase II (Co II) from four different apterygotens Cryptopygus nanjiensis (Collembola), Neanura latior (Collembola), Gracilentulus maijiawensis (Protura) and Lepidocampa weberi (Diplura) ...
关键词：Cryptopygus nanjiensis Apterygota MITOCHONDRIAL CYTOCHROME OXIDASE II gene evolution. 
Phylogenetic relationships of five pika species (genus Ochotona) based on mitochondrial DNA restriction maps
《Science China(Life Sciences)》1996年第2期113-122,共10页于宁 郑昌琳 施立明 王文 兰宏 张亚平 
Project supported by the National Natural Science Foundation of China,the Foundation of the Chinese Academy of Sciences for Taxonomy and Fauna,and Laboratory of Cellular and Molecular Evolution,the Chinese Academy of Sciences.
Restriction site mapping of mitochondrial DNA (mtDNA) with 16 restriction endonucleases was used to examine the phylogenetic relationships of Ochotona cansus, O. huangensis, O. thibetana, O. curzoniae and O. erythroti...
关键词：pitas (Ochotona) mitochondrial DNA RESTRICTION maps taxonomy phytogeny. 
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