supported by Major International(Regional)Joint Research Project of National Natural Science Foundation of China(No.81120108002);National Natural Science Foundation of China(No.30930105;No.30873058);China Medical Board Distinguished Professorships Award(No.F510000/G16916404)
supported by the National Natural Science Foundation of China(No.30930105;30873058;30770785);the National Basic Research Development Program of China(No.2007CB512005);China Medical Board Distinguished Professorships Award(No.F510000/G16916404)