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All-trans Retinoic Acid Diminishes Collagen Production in a Hepatic Stellate Cell Line via Suppression of Active Protein-1 and c-Jun N-terminal Kinase Signal被引量：8
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第6期726-733,共8页叶媛 但自力 
Following acute and chronic liver injury,hepatic stellate cells (HSCs) become activated to undergo a phenotypic transformation into myofibroblast-like cells and lose their retinol content,but the mechanisms of retinoi...
关键词：all trans-retinoic acid liver stellate cells COLLAGEN transforming growth factor β 1 active protein-1 c-Jun N-terminal kinase. 
N-terminal pro-brain natriuretic peptide but not high-sensitivity C-reactive protein is related to severity of coronary artery stenosis in patients with acute coronary syndrome被引量：1
《Journal of Geriatric Cardiology》2010年第2期101-105,共5页Shi-Jun Li Zhi-Jun Sun Dan-Dan Li Geng Qian Ting-Shu Yang Xiao-Ying Li 
Objective Biochemical indicators such as N-terminal pro-brain type natriuretic peptide（NT pro-BNP）and high-sensitivity Creactive protein（hsCRP）predict mortality in acute coronary syndrome（ACS）.However,little is ...
关键词：N-terminal pro-brain natriuretic peptide high-sensitivity C-reactive protein coronary artery stenosis acute coronary syndrome 
Activation and involvement of JNK1/2 in hydrogen peroxideinduced neurotoxicity in cultured rat cortical neurons被引量：3
《Acta Pharmacologica Sinica》2004年第5期630-636,共7页WeiWANG CanGAO Xiao-yuHOU YongLIU Yan-yanZONG Guang-yiZHANG 
The present study was supported by grants from the Educa-tion Departmental Natural Science Research Funds of JiangsuProvince of China (No 99KJB180002; 99KJD180004) and theNational Natural Science Foundation of China (No 39770177).2
AIM: To investigate the role of c-Jun N-terminal protein kinase 1 and 2 (JNK1/2) and the main signal pathway forits activation in hydrogen peroxide (H2O2) induced apoptotic-like cortical cell death. METHODS: Using th...
关键词：c-Jun N-terminal protein kinase calcium N-methylaspartate receptors hydrogen peroxide SIGNALTRANSDUCTION apoptosis cerebral cortex 
Pomegranate extract inhibits EMT in clear cell renal cell carcinoma in a NF-κB and JNK dependent manner被引量：1
《Asian Journal of Urology》2015年第1期38-45,共8页Jiabin An Yanchuan Guo Ting Wang Allan J.Pantuck Matthew B.Rettig 
Objective:Clear cell renal cell carcinoma(ccRCC)is the most common subtype of renal cell carcinoma(RCC)and is characterized by biallelic inactivation of the von Hippel-Lindau(VHL)tumor suppressor gene.One effect of VH...
关键词：Pomegranate extract von Hippel-Lindau(VHL)tumor suppressor Clear cell renal cell carcinoma c-Jun N-terminal kinase Epithelial to mesenchymal transition Nuclear factor kappa B 
8-bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK被引量：38
《World Journal of Gastroenterology》2010年第27期3385-3393,共9页Xiao-Hong Yang  Jian-Guo Cao  Hong-Lin Xiang  Fei Liu  Yuan Lv Hunan Province  China Xing Zheng 
Supported by Hunan Provincial Natural Science Foundation of China,No.03JJY5009
AIM:To investigate whether the apoptotic activities of 8-bromo-7-methoxychrysin(BrMC) involve reactive oxygen species(ROS) generation and c-Jun N-terminal kinase(JNK) activation in human hepatocellular carcinoma cells...
关键词：Hepatocellular carcinoma 8-bromo-7-methoxychysin CHRYSIN Reactive oxygen species Jun N-terminal kinase 
Clinical presentation and early predictors for poor outcomes in pediatric myocarditis:A retrospective study被引量：12
《World Journal of Clinical Cases》2019年第5期548-561,共14页Moises Rodriguez-Gonzalez Maria Isabel Sanchez-Codez Manuel Lubian-Gutierrez Ana Castellano-Martinez 
BACKGROUND Myocarditis is an important cause of morbidity and mortality in children, leading to long-term sequelae including chronic congestive heart failure, dilated cardiomyopathy, heart transplantation, and death. ...
关键词：MYOCARDITIS Children ECHOCARDIOGRAPHY N-TERMINAL pro-brain NATRIURETIC peptide Myocardial ischemia Cardiac magnetic resonance imaging Heart transplantation DILATED CARDIOMYOPATHY 
Predictive value of N-terminal pro-brain natriuretic peptide in combination with the sequential organ failure assessment score in sepsis被引量：11
《Chinese Medical Journal》2012年第11期1893-1898,共6页JU Min-jie ZHU Du-ming TU Guo-wei HE Yi-zhou XUE Zhang-gang LUO Zhe WU Zhao-guang 
Background The prognostic power of n-terminal pro-brain natriuretic peptide （NT-proBNP） in sepsis is disputable and unstable among different models. We attempt to evaluate the prognostic potential of NT-proBNP in co...
关键词：SEPSIS PROGNOSIS N-terminal pro-brain natriuretic peptide sequential organ failure assessment score COMBINATION 
Hydroxychavicol,a polyphenol from Piper betle leaf extract,induces cell cycle arrest and apoptosis in TP53-resistant HT-29 colon cancer cells被引量：3
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第2期112-122,共11页Aiysvariyah RAJEDADRAM Kar Yong PIN Sui Kiong LING See Wan YAN Mee Lee LOOI 
supported by the Taylor’s Research Grant Scheme(No.TRGS/MFS/2/2013/SBS/003),Malaysia。
This study aims to elucidate the antiproliferative mechanism of hydroxychavicol(HC).Its effects on cell cycle,apoptosis,and the expression of c-Jun N-terminal kinase(JNK)and P38 mitogen-activated protein kinase(MAPK)i...
关键词：Piper betle Hydroxychavicol(HC) Cell cycle APOPTOSIS c-Jun N-terminal kinase(JNK) P38 mitogen-activated protein kinase(MAPK) 
Vasopressin decreases neuronal apoptosis during cardiopulmonary resuscitation被引量：2
《Neural Regeneration Research》2014年第6期622-629,共8页Chi Ma Zhe Zhu Xu Wang Gang Zhao Xiaoliang Liu Rui Li 
The American Heart Association and the European Resuscitation Council recently recommend- ed that vasopressin can be used for cardiopulmonary resuscitation, instead of epinephrine. However, the guidelines do not discu...
关键词：nerve regeneration brain injury cardiopulmonary resuscitation EPINEPHRINE VASOPRESSIN c-Jun N-terminal kinase p38 mitogen activated protein kinase cardiac arrest neural regeneration 
A sting in the tail： the N-terminal domain of the androgen receptor as a drug target被引量：3
《Asian Journal of Andrology》2016年第5期687-694,共8页Amy E Monaghan Iain J McEwan 
The role of androgen receptor （AR） in the initiation and progression of prostate cancer （PCa） is well established. Competitive inhibition of the AR ligand-binding domain （LBD） has been the staple of antiandrogen...
关键词：androgen receptor INHIBITOR intrinsically disordered structure N-terminal domain prostate cancer small molecules 
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