-
在结果中检索

检索结果分析

结果分析中...
检索条件："关键词=REPROGRAMMING "
共 条 记 录，以下是1-10

发文量、被引量趋势图

全选清除导出
参考文献引证文献引用追踪
视图：
排序：
显示条数：
NOX4 promotes tumor progression through the MAPK-MEK1/2-ERK1/2 axis in colorectal cancer
《World Journal of Gastrointestinal Oncology》2024年第4期1421-1436,共16页Yu-Jie Xu Ya-Chang Huo Qi-Tai Zhao Jin-Yan Liu Yi-Jun Tian Lei-Lei Yang Yi Zhang 
Supported by Henan Province Medical Science and Technology Research Provincial and Ministry Co-constructed Projects,No.SBGJ202101010;Major Public Welfare Projects in Henan Province,No.201300310400;Joint Construction Project of Henan Medical Science and Technology Research Plan,No.LHGJ20220050;Major Science and Technology Project of Henan Province,No.221100310100.
BACKGROUND Metabolic reprogramming plays a key role in cancer progression and clinical outcomes;however,the patterns and primary regulators of metabolic reprogramming in colorectal cancer(CRC)are not well understood.A...
关键词：Colorectal cancer Metabolic reprogramming METASTASIS Nicotinamide adenine dinucleotide phosphate oxidase 4 Mitogen-activated protein kinase signaling 
激光重编码形状可重构磁性机器人
《中国激光》2024年第23期34-42,共9页张倩倩 李瑞 陶源 李家文 
国家重点研发计划(2021YFF0502700);国家自然科学基金(52075516);安徽省科技重大专项(202103a05020005)。
磁性机器人可以在磁场驱动下实现远程、快速和灵活的运动,而现有磁性机器人受限于固定的磁畴和柔软的基质,其变形能力和承载载荷有限,难以广泛应用于复杂环境。开发了一种磁畴可重编码的形状记忆复合材料,通过激光与磁场的协同作用,对...
关键词：近红外激光 形状记忆薄膜 重编码 形状重构 磁性机器人 
Macrophage metabolism reprogramming EGCG-Cu coordination capsules delivered in polyzwitterionic hydrogel for burn wound healing and regeneration
《Bioactive Materials》2023年第11期251-264,共14页Qinghua Li Huijuan Song Shuangyang Li Pengbo Hu Chuangnian Zhang Ju Zhang Zujian Feng Deling Kong Weiwei Wang Pingsheng Huang 
the National Natural Science Foundation of China(No.82272162,82001954);Fundamental Research Funds for the Central Universities (3332021067, 2019PT350005);Natural Science Fund for Distinguished Young Scholars of Tianjin (21JCJQJC00020);CAMS Innovation Fund for Medical Sciences (2021-I2M-1-052, 2021- I2M-1-058, 2021-I2M-1-065);Tianjin Innovation and Promotion Plan Key Innovation Team of Implantable and Interventional Biomedical Materials.
Excessive reactive oxygen species(ROS)at severe burn injury sites may promote metabolic reprogramming of macrophages to induce a deteriorative and uncontrolled inflammation cycle,leading to delayed wound healing and r...
关键词：ROS scavenging Hydrogel dressing EGCG-Cu capsule Metabolic reprogramming Burn wound healing 
Differential neuronal reprogramming induced by NeuroD1 from astrocytes in grey matter versus white matter被引量：11
《Neural Regeneration Research》2020年第2期342-351,共10页Min-Hui Liu Wen Li Jia-Jun Zheng Yu-Ge Xu Qing He Gong Chen 
supported in part by the National Natural Science Foundation of China(Grant No.31701291 to WL,U1801681 to GC);the China Postdoctoral Science Foundation(Grant No.2016M602600 to WL);the Guangdong Grant ‘Key Technologies for Treatment of Brain Disorders’(Grant No.2018B030332001 to GC);the Internal Funding of Jinan University,China(Grant No.21616110 to GC)
A new technology called in vivo glia-to-neuron conversion has emerged in recent years as a promising next generation therapy for neural regeneration and repair. This is achieved through reprogramming endogenous glial ...
关键词：ASTROCYTE CONVERSION efficiency corpus callosum cortex grey MATTER in vivo cell CONVERSION NeuroD1 neuron REPROGRAMMING STRIATUM white MATTER 
Acid–base Homeostasis and Implications to the Phenotypic Behaviors of Cancer
《Genomics, Proteomics & Bioinformatics》2023年第6期1133-1148,共16页Yi Zhou Wennan Chang Xiaoyu Lu Jin Wang Chi Zhang Ying Xu 
supported by the National Science Foundation of USA(Grant No.2047631)and partially by Georgia Research Alliance,USA。
Acid–base homeostasis is a fundamental property of living cells,and its persistent disruption in human cells can lead to a wide range of diseases.In this study,we conducted a computational modeling analysis of transc...
关键词：Acid-basehomeostasis Cancer microenvironment Metabolic reprogramming Fenton reaction Ironmetabolism 
Soluble expression of recomb inant cMyc,Klf4,Oct4,and Sox2 proteins in bacteria and transduction into living cells被引量：5
《International Journal of Ophthalmology(English edition)》2017年第4期560-566,共7页Guo-Dan Liu Shi-Feng Zhou Xu-Chen Ding Chun-Lai Fang Shu-Yong Mi Xiang-Chun Gao Qing Han 
Supported by the Foundation of Heilongjiang Provincial Foundation for Youths Project(No.QC2011C119)
AIM：To develop a new method to produce recombinant reprogramming proteins,c Myc,Klf4,Oct4,and Sox2,in soluble format with low cost for the generation of induced pluripotent stem cells（i PSCs）.METHODS：A short polyp...
关键词：reprogramming proteins induced pluripotent stem cells soluble expression protein transduction 
Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury被引量：1
《Neural Regeneration Research》2024年第3期629-635,共7页Jingzhou Liu Xin Xin Jiejie Sun Yueyue Fan Xun Zhou Wei Gong Meiyan Yang Zhiping Li Yuli Wang Yang Yang Chunsheng Gao 
supported by the National Natural Science Foundation of China,No.82073783(to YY);the Natural Science Foundation of Beijing,No.7212160(to YY).
Traumatic brain injury results in neuronal loss and glial scar formation.Replenishing neurons and eliminating the consequences of glial scar formation are essential for treating traumatic brain injury.Neuronal reprogr...
关键词：AAV9P1 ASTROCYTES astrocyte-to-neuron conversion GFAP promoter glial scar induced neurons neuronal reprogramming P1 peptide PTBP1 traumatic brain injury 
Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future
《Neural Regeneration Research》2025年第4期946-959,共14页Zhiyuan Yin Jiahui Kang Xuan Cheng Hui Gao Shujia Huo Haiwei Xu 
supported by the National Natural Science Foundation of China,No.31930068;National Key Research and Development Program of China,Nos.2018YFA0107302 and 2021YFA1101203(all to HX).
Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased states.In lower vertebrates like zebrafish,these cells assume responsibi...
关键词：cell fusion chemical small-molecules EPIGENETIC extracellular matrix immune metabolic MICE Müller glia neurodegenerative diseases REPROGRAMMING retina regeneration 
Cellular reprogramming and inherited peripheral neuropathies: perspectives and challenges
《Neural Regeneration Research》2015年第6期894-896,共3页Mario A.Saporta 
Inherited peripheral neuropathies （or Charcot-Marie-Tooth disease, CMT） are a phenotypically and genetically heterogeneous group of disorders, which are currently untreatable. They are the most common inherited neur...
关键词：gene CMT Cellular reprogramming and inherited peripheral neuropathies perspectives and challenges LITAF 
核移植胚胎甲基化过程相关调控因子表达情况研究
《黑龙江畜牧兽医》2018年第1期21-26,共6页王巍 付茂忠 易军 方东辉 唐慧 甘佳 赖松家 
“十二五”农村领域国家科技计划项目(2015BAD03B04-3);四川省应用基础项目(2015JY0181);四川省科技支撑计划项目(2015NZ0020);四川省育种攻关项目(2016NYZ0050)
为了研究体细胞移入去核的卵母细胞后甲基化重编码程序的模式变化情况,试验对10个参与甲基化重编程的重要因子在5个发育阶段的早期核移植胚胎(配子期、S期、2-cell期、8-cell期和桑葚期)中表达量的变化模式进行了荧光定量研究。结果表明...
关键词：体细胞核移植 甲基化 重编程 甲基化转移酶 甲基化结合蛋白 
全选清除导出
共45页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部