Stem cells are defined by their capacity for both self-renewal and directed differentiation; thus, they represent great promise for regenerative medicine. Historically, stem cells have been categorized as either embry...
Supported by the National Institutes of Health,No.NIH BUILD Pilot 8UL1GM118970-02,NIH 1SC2HL134642-01;the National Science Foundation,NSFPREM program,No.DMR:1205302;the PREM Center for Energy and Biomaterials,No.DMR:1827745
Currently, there does not exist a strategy that can reduce diabetes and scientists are working towards a cure and innovative approaches by employing stem cellbased therapies. On the other hand, bioprinting technology ...
Intervertebral disc degeneration is the main cause of low back pain.In the past 20 years,the injection of mesenchymal stromal cells(MSCs)into the nucleus pulposus of the degenerative disc has become the main approach ...
supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542201;Program for Innovative Research Team in University of Ministry of Education of China,No.IRT1201;the National Natural Science Foundation of China,No.31271284,31171150,81171146,30971526,31100860,31040043;Program for New Century Excellent Talents in University of Ministry of Education of China,No.BMU20110270;the Natural Science Foundation of Beijing of China,No.7142164
We examined the restorative effect of modified biodegradable chitin conduits in combination with bone marrow mesenchymal stem cell transplantation after right spinal cord hemisection injury. Immunohistochemical staini...
Mesenchymal stem cells (MSCs) have been isolated and identified separately from the three com- ponents of intervertebral disc, i.e. annulus fibrosus (AF), nucleus pulposus (NP), and cartilage end- plate (CEP)....
National Natural Science Foundation;Grant number:30370567,30170374
Objective:To restore cardiac autonomic pace function by autologous trans- plantation and committed differentiation of hone marrow mesenchymal stern cells, and explore the technique for the treatment of sick sinus syn...
Supported by the National Key R&D Program of China (No.2016YFC1100100);the Key R&D Program of Shaanxi Province (No.2018ZDXM-SF-056);the Health and Family Planning Research Fund Project of Shaanxi Province (No.2016C004);the Key Research and Development Program of Shaanxi Province (No.2019SF-196);the Research Talent Project of Xi’an Municipal Health Commission (No.J201902037)。
Corneal stroma-derived mesenchymal stem cells(CS-MSCs) are mainly distributed in the anterior part of the corneal stroma near the corneal limbal stem cells(LSCs). CS-MSCs are stem cells with self-renewal and multidire...
the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea,No.HI20C1405。
BACKGROUND There is still no consensus on which concentration of mesenchymal stem cells(MSCs)to use for promoting fracture healing in a rat model of long bone fracture.AIM To assess the optimal concentration of MSCs f...
This study was supported by a grant from National Natural Science Foundation of China (No. 81070055).
Background Acute lung injury (ALl) and end-stage acute respiratory distress syndrome (ARDS) were among the most common causes of death in intensive care units. The activation of an inflammatory response and the da...
This work was supported by the Guangdong Provincial Science and Technology Plan Project[No.2017A030303083];Guangzhou Science and Technology Plan Project[No.201804010387];National Natural Science Foundation of China(NSFC)[No.82074462,81774339,81872860];National Major Special Projects for the Creation and Manufacture of New Drugs[No.2019ZX09301104];Guangdong Provincial Science and Technology Plan Project[No.2017A030303083];Guangzhou Science and Technology Plan Project[No.201804010387];Natural Science Foundation of Guangdong Province,China[No.2021A1515011003].
N^(6)-methyladenosine(m^(6)A)is the most abundant posttranscriptional methylation modification that occurs in mRNA and modulates the fine-tuning of various biological processes in mammalian development and human disea...