5-AZACYTIDINE

作品数：20被引量：62H指数：4
导出分析报告
相关作者：邓方阁张秀英李玉林曲丽梅孙亿更多>>
相关机构：吉林大学山东农业大学第四军医大学第四军医大学唐都医院更多>>
相关期刊：《Journal of Ocean University of China》《Acta Pharmacologica Sinica》《Science China Chemistry》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Biological Evaluation of a Novel 2’-Fluoro Derivative 5-Azacytidine as a Potent DNA Methyltransferase Inhibitor
《Pharmacology & Pharmacy》2024年第11期388-402,共15页Elena Kalinichenko Tatyana Bozhok Roman Zilberman Alesya Panibrat 
Background: DNA methyltransferases (DNMTs) are key epigenetic regulatory enzymes involved in the expression of many genes and are considered as an attractive target for cancer treatment, especially hematological malig...
关键词：Drug Discovery DECITABINE 2’-Fluorodeoxy-Arabino Analog DNA Methyltransferase Enzyme Inhibition Cell Cycle Apoptosis 
Effects of 5-Azacytidine(AZA)on the Growth,Antioxidant Activities and Germination of Pellicle Cysts of Scrippsiella acuminata(Dinophyceae)
《Journal of Ocean University of China》2023年第6期1660-1668,共9页WANG Zhaohui ZHANG Jianneng TANG Tao ZHANG Yuning HU Ren 
supported by the National Natural Science Foundation of China(No.42076141).
In this study,we investigated the effects of different concentrations of 5-azacytidine(AZA),a DNA methyltransferase in-hibitor,on the growth,antioxidant activities and germination of pellicle cysts of Scrippsiella acu...
关键词：5-AZACYTIDINE Scrippsiella acuminata pellicle cysts toxicity superoxide dismutase glutathione MALONDIALDEHYDE 
DNA Methyltransferase Inhibitors Induce Cerebral Dopamine Neurotrophic Factor Expression in C6 Glioma Cells
《American Journal of Molecular Biology》2023年第3期170-182,共13页Sumeya Z. Mukhtar Lennard P. Niles 
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) are involved in neuroprotection and mitigating endoplasmic reticulum (ER) stress in the brain and peripheral ...
关键词：CDNF MANF 5-AZACYTIDINE 5-Aza-2’-deoxycytidine ZEBULARINE Gene Expression 
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho被引量：8
《Acta Pharmacologica Sinica》2022年第10期2609-2623,共15页Wei Zhou Min-min Chen Hui-ling Liu Zi-lin Si Wen-hui Wu Hong Jiang Lin-xiao Wang Nosratola D.Vaziri Xiao-fei An Ke Su Cheng Chen Ning-hua Tan Zhi-hao Zhang 
This work was financially supported by the National Natural Science Foundation of China(Grants 81703691,81803694);the Fundamental Research Funds for the Central Universities(Grant No.2632020ZD07).
Renal fibrosis is an unavoidable end result of all forms of progressive chronic kidney diseases(CKD).Discovery of efficacious drugs against renal fibrosis is in crucial need.In a preliminary study we found that a deri...
关键词：renal fibrosis DIHYDROARTEMISININ DNMT1 KLOTHO 5-AZACYTIDINE affinity-based proteome profiling 
Triterpenoid content and expression of triterpenoid biosynthetic genes in birch(Betula platyphylla Suk)treated with 5-azacytidine
《Journal of Forestry Research》2020年第5期1843-1850,共8页Fansuo Zeng Xiaoyi Li Rui Qie Leilei Li Minghao Ma Yaguang Zhan 
The work was supported by The Fundamental Research Funds for the Central Universities(2572017EA05);the National Natural Science Foundation of China(31870588).
DNA methylation is widespread in plants and associated with plant development and defense mechanisms.However,the relationship between DNA methylation and plant secondary metabolism has rarely been reported.Here,when b...
关键词：5-AZACYTIDINE METHYLATION Suspension cells Triterpenoids biosynthesis 
Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitors被引量：6
《Chinese Medical Journal》2020年第6期699-715,共17页Qing-Yu Xu Li Yu 
This work was supported by grants from the National Natural Science Foundation of China(No.81670162,No.81970151,and No.81470010).
Epigenetic regulation includes changes of DNA methylation and modifications of histone proteins and is essential for normal physiologic functions,especially for controlling gene expression.Epigenetic dysregulation pla...
关键词：Acute MYELOID leukemia DECITABINE 5-AZACYTIDINE HISTONE DEACETYLASE inhibitors Intensive chemotherapy 
Trans-generational effects in the clonal invader Alternanthera philoxeroides被引量：4
《Journal of Plant Ecology》2020年第1期122-129,共8页Rubén Portela Bi-Cheng Dong Fei-Hai Yu Rodolfo Barreiro Sergio R.Roiloa Dalva MSilva Matos 
supported by a mobility grant from the University of A Coruña(Inditex-UDC 2017 program);This is a contribution from the Alien Species Network(Ref.ED431D 2017/20-Xunta de Galicia,Autonomous Government of Galicia);.D.M.S.M.thanks the Brazilian Conselho Nacional de Desenvolvimento Científico e Tecnológico/CNPq(307839/2014-1)for her Research Fellowship.
Aims Recent studies have revealed heritable phenotypic plasticity through vegetative generations.In this sense,changes in gene regulation induced by the environment,such as DNA methylation(i.e.epigenetic changes),can ...
关键词：5-AZACYTIDINE alligator weed clonal growth DNA methylation epigenetic variation plant invasions 
Transplantation of 5-azacytidine treated cardiac fibroblasts improves cardiac function of infarct hearts in rats被引量：1
《Chinese Medical Journal》2010年第18期2586-2592,共7页TANG Cheng-chun MA Gen-shan CHEN Ji-yuan 
Background Cellular cardiomyoplasty by transplantation of various cell types has been investigated as potential treatments for the improvement of cardiac function after myocardial injury. A major barrier for the clini...
关键词：cardiac fibroblasts myocardial infarction TRANSPLANTATION 5-AZACYTIDINE 
Induced Differentiation of Adipose-derived Stromal Cells into Myoblasts
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第3期285-290,共6页吴桂珠 郑秀 江忠清 王金华 宋岩峰 
supported by grants from Research Foundations for Young Scholars,Health Department of Fujian Province,China(No.2008-1-27);Research Foundations of the Health Department of the Nanjing Military Zone of the People's Liberation Army,China(No.08MA099);Nursery Scientific Research Foundation for Youth of Fujian Medical University,China(No.2010MP004)
This study aimed to induce the differentiation of isolated and purified adipose-derived stromal cells(ADSCs) into myoblasts,which may provide a new strategy for tissue engineering in patients with stress urinary incon...
关键词：adipose-derived stromal cells 5-AZACYTIDINE MYOBLASTS stress urinary incontinence DIFFERENTIATION 
The Experimental Study on Constructing the Tissue Engineered Myocardium-like Tissue in vitro with Bone Mesenchymal Stem Cells
《Chinese Journal of Biomedical Engineering(English Edition)》2010年第1期8-15,共8页XING Wan-hong MA Jie GUO Guang-wei LI Xin-hua XI Hu-yu 
The Tackle Key Problems in Science and Technology, Shanxi Province; grant number: 20080311061-2
Objective:Unlike other tissues,myocardium has not substitute whick can be used to repair damaged cardiac tissue.This paper proposes engineering 3-D myocardium-like tissue constructs in vitro with bone mesenchymal stem...
关键词：tissue engineering bone mesenchymal stem cells 5-AZACYTIDINE MYOCARDIUM in vitro 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部