Acknowledgements This work was supported by the National Natural Science Foundation of China (30770868, 30971170), the Natural Science Foundation of Hunan Province, China (No 06JJ5055) and the Science & Technology Department of Hunan Province (No 04FJ4064). The authors acknowledge and express appreciation to Rhona KELLY for editing the manuscript.
Cholesterol efflux from lipid-loaded cells is a key athero-protective event that counteracts cholesterol uptake. The imbalance between cholesterol efflux and uptake determines the prevention or development of atherosc...
Aim: To explore the mechanisms involved in ox-LDL transcytosis across endothelial cells and the role of caveolae in this process. Methods: An in vitro model was established to investigate the passage of oxidized low...