国家重点基础研究发展计划(2012CB518403)

作品数：3被引量：42H指数：3
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相关期刊：《Acta Pharmacologica Sinica》《Acta Pharmaceutica Sinica B》更多>>
相关主题：CYTOCHROMEXUESHUANTONGION-TRANSPORTGINSENOSIDESPANAX更多>>
相关领域：医药卫生农业科学化学工程更多>>
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Intravenous formulation of Panax notoginseng root extract:human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions被引量：17
《Acta Pharmacologica Sinica》2019年第10期1351-1363,共13页Salisa Pintusophon Wei Niu Xiao-na Duan Olajide E Olaleye Yu-hong Huang Feng-qing Wang Yan-fen Li Jun-ling Yang Chuan Li 
This work was supported in part by the National Key R&D Program of China(Grant 2018YFC1704500);by the National Science and Technology Major Project of China"Key New Drug Creation and Manufacturing Program"(Grants 2012ZX09101201-005 and 2017ZX09301012-006);by the National Natural Science Foundation of China(Grant 81673582);by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant XDA12050306);and by the National Basic Research Program of China(Grant 2012CB518403).
XueShuanTong,a lyophilized extract of Panax notoginseng roots(Sanqi)for intravenous administration,is extensively used as add-on therapy in the treatment of ischemic heart and cerebrovascular diseases and comprises th...
关键词：GINSENOSIDE CYTOCHROME P4503A organic anion-transporting polypeptide 1B3 herbal medicine-drug interactions XUESHUANTONG PANAX notoginseng 
High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care被引量：15
《Acta Pharmaceutica Sinica B》2019年第5期1035-1049,共15页Jian Li Olajide E.Olaleye Xuan Yu Weiwei Jia Junling Yang Chuang Lu Songqiao Liu Jingjing Yu Xiaona Duan Yaya Wanga Kai Dong Rongrong He Chen Cheng Chuan Li 
funded by grants from the National Science&Technology Major Project of China “Key New Drug Creation and Manufacturing Program”(2017ZX09301012006);the National Basic Research Program of China(2012CB518403);the National Natural Science Foundation of China(81503345);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA12050306)
Managing the dysregulated host response to infection remains a major challenge in sepsis care. Chinese treatment guideline recommends adding Xue Bi Jing, a five-herb medicine, to antibioticbased sepsis care. Although ...
关键词：XUEBIJING Antibiotic Combination DRUG therapy SEPSIS PHARMACOKINETIC compatibility Herb-drug interaction 
Sensitive assay for measurement of volatile borneol, isoborneol, and the metabolite camphor in rat pharmacokinetic study of Borneolum （Bingpian） and Borneolum syntheticum （synthetic Bingpian）被引量：15
《Acta Pharmacologica Sinica》2013年第10期1337-1348,共12页Chen CHENG Xin-wei LIU Fei-fei DU Mei-juan LI Fang XU Feng-qing WANG Yang LIU Chuan LI Yan SUN 
Aim： Both Bomeolum （Chinese name Bingpian; dextrorotatory borneol） and Borneolum syntheticum （synthetic Bingpian; a mixture of optically inactive borneol and isoborneol） have been used for medicinal purposes in C...
关键词：pharmacokinetics BORNEOL ISOBORNEOL CAMPHOR Bingpian liquid-liquid microextraction gas chromatography/mass spec-trometry large-volume injection 
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