国家重点基础研究发展计划(MOST)

作品数：18被引量：71H指数：6
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Persistent inflammation and neuronal loss in the mouse brain induced by a modified form of attenuated herpes simplex virus type I被引量：2
《Virologica Sinica》2023年第1期108-118,共11页Erlin Wang Xinwei Huang Yunshuang Ye Shiqing Zou Guijun Chen Liping Yang Nigel W.Fraser Fukai Bao Jumin Zhou Xia Cao 
supported by grants from the National Natural Science Foundation of China-Yunnan Joint Found(NSFC,U2202215,U1602226);the National Natural Science Foundation of China(NSFC,81672040 to J.Zhou,8206306 to X.Cao,and 31802026 to L.Li);the Ministry of Science and Technology of China(MOST,2018YFC2000402,2018YFE0203700);the Ministry of Science and Technology of China Foreign Expert Program to J.Zhou(G2021061008L);the CAS“Light of West China”Program(xbzg-zdsys-201909)to J.Zhou,a Thousand Foreign Talent scholarship from Yunnan Province and High-end Foreign Expert Project of Yunnan Revitalization Talent Support Program to J.Zhou;the Technology Innovation Team of Kunming Medical University(CXTD201804);the International Science and Technology Cooperation Project(2017IB011);the Yunnan Training Project for Medical Talents(L-2017014);the biomedical Special Project of the Department of Science and Technology of Yunnan Province(202102AA100007-4)to X.Cao;the Chinese Academy of Sciences President's International Fellowship Initiative(PIFI,2019VBA0045)to N.W.Fraser;the China Postdoctoral Science Foundation(2022MD713758)to E.Wang;the Medical reserve Talents Training Program of Yunnan Provincial Health Commission of China(H-2019059)to X.Huang;the Yunnan Fundamental Research Projects(202201AT070195)to Y.Ye.;Open Research Fund HXDT-2019-1 to J.Zhou.
Herpes simplex virus-1(HSV-1)is a widespread neurotropic virus that can reach the brain and cause a rare but acute herpes simplex encephalitis(HSE)with a high mortality rate.Most patients present with changes in neuro...
关键词：Herpes simplex virus-1(HSV-1) Herpes simplex encephalitis(HSE) ICP34.5 NEUROINFLAMMATION Neuronal loss 
Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications
《Science China(Life Sciences)》2022年第7期1342-1356,共15页Hui Zhao Jianping Zhao Di Wu Zhaolin Sun Yang Hua Min Zheng Yumei Liu Qi Yang Xiahe Huang Yuan Li Yueshan Piao Yingchun Wang Sin Man Lam Huijuan Xu Guanghou Shui Yongjun Wang Haifeng Yao Liangxue Lai Zhuo Du Jidong Mi Enqi Liu Xunming Ji Yong Q.Zhang 
supported by the National Natural Science Foundation of China(NSFC,81620108011);the Ministry of Science and Technology of China(MOST,2017YFC1308401);supported by NSFC(31830036 and 31921002);the Beijing Municipal Science&Technology Commission(Z181100001518001);MOST(2019YFA0707100);the Chinese Academy of Sciences(XDBS1020100)。
Atherosclerotic cardiovascular disease resulting from dysregulated lipid metabolism is the leading cause of morbidity and mortality worldwide.Apolipoprotein E(ApoE)plays a critical role in cholesterol metabolism.Knock...
关键词：ApoE ATHEROSCLEROSIS HYPERCHOLESTEROLEMIA GANGRENE stroke 
Article Navigation Syntelin inhibits triple-negative breast cancer cell proliferation and metastasis被引量：1
《Journal of Molecular Cell Biology》2021年第11期834-837,共4页McKay Mullen Fengrui Yang Jun Cao Yang Cao Xu Liu Gee Young Lee Tao Li William Yao Zhihong Yang Jiahai Zhang Kela Johnson Felix Aikhionbare Yong Chen Xinjiao Gao Dongmei Wang Xia Ding Hadiyah-Nicole Green Xing Liu Xuebiao Yao 
supported by grants from the Ministry of Science and Technology of China(MOST,2017YFA0503600);the National Natural Science Foundation of China(NSFC,81630080,31621002,32090040,21922706,91854203,and 91853115);China Postdoctoral Science Foundation grant(2019M662181);the US National Institutes of Health(NIH,DK56292,DK115812,S21MD000101,and CA164133).
Dear Editor,The hallmarks of cancer comprise several distinct biological characteristics acquired during the multistep development of human tumors with the unique feature of genomic instability(Shen,2011).These cancer...
关键词：METASTASIS BREAST 
Virtual and augmented reality technologies for emergency management in the built environments: A state-of-the-art review被引量：7
《Journal of Safety Science and Resilience》2021年第1期1-10,共10页Yiqing Zhu Nan Li 
This material is based on work supported by the National Key R&D Program of China under Grant No.2017YFC0803300;the National Nat-ural Science Foundation of China(NSFC)under Grant No.71603145;the Humanities and Social Sciences Fund of the Ministry of Educa-tion of China(MOE)under Grant No.16YJC630052;The authors are grateful for the support of the Ministry of Science and Technology of China(MOST),NSFC and MOE.
With the rapid technological advancements in recent decades,virtual reality(VR)and augmented reality(AR)technologies have been increasingly adopted to address various challenges in emergency management in the built en...
关键词：Virtual reality Augmented reality Emergency management Built environment Literature review 
Magnetic-brightening and control of dark exciton in CsPbBr3 perovskite被引量：2
《Science China Materials》2020年第8期1503-1509,共7页Zhongtai Shi Shoaib Muhammad Longjiang Deng Zhen Liu Lei Bi Linbo Zhang Li Zhang Peiheng Zhou Haiyan Chen Haipeng Lu Jianliang Xie Dong Li Anlian Pan Bo Peng 
supported by the National Natural Science Foundation of China(51602040,51872039,51525202 and 51902098);the Science and Technology Program of Sichuan(M112018JY0025);Scientific Research Foundation for New Teachers of UESTC(A03013023601007);the Ministry of Science and Technology of China(MOST,2016YFA0300802)。
Exploring the fine-structure of cesium lead bromide(CsPbBr3)perovskite nanocrystals(NCs)is not only vital to fundamental understanding of recombination mechanism of exciton but also crucial for improving the performan...
关键词：perovskite materials CsPbBr3 dark exciton magnetic field BRIGHTENING 
Global sensitivity analysis of wheat grain yield and quality and the related process variables from the DSSAT-CERES model based on the extended Fourier Amplitude Sensitivity Test method被引量：11
《Journal of Integrative Agriculture》2019年第7期1547-1561,共15页LI Zhen-hai JIN Xiu-liang LIU Hai-long XU Xin-gang WANG Ji-hua 
supported by the National Natural Science Foundation of China(41701375,41601369,and 41471285);the European Space Agency(ESA)and Ministry of Science and Technology of China(MOST)Dragon 4 Cooperation Programme(32275-1)
A crop growth model,integrating genotype,environment,and management factor,was developed to serve as an analytical tool to study the influence of these factors on crop growth,production,and agricultural planning.A maj...
关键词：global sensitivity analysis DSSAT EFAST WHEAT yield GRAIN protein content 
Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts被引量：7
《Bone Research》2018年第3期226-237,共12页Jun Sun Joerg Ermann Ningning Niu Guang Yan Yang Yang Yujiang Shi Weiguo Zou 
supported in part by grants from 973 Program from the Chinese Ministry of Science and Technology (MOST) [2014CB964704, 2015CB964503];the National Natural Science Foundation of China (NSFC) [31371463];the "1000 Young Talents Program of China" and "the National Science Fund for Excellent Young Scholars" (NSFC) [81322027]
Multiple regulatory mechanisms control osteoblast differentiation and function to ensure unperturbed skeletal formation and remodeling. In this study we identify histone lysine-specific demethylase 1(LSD1/KDM1 A) as a...
关键词：LSD1/KDM1A HMSCS 
Sources, evolution and impacts of EC and OC in snow on sea ice： a measurement study in Barrow, Alaska被引量：7
《Science Bulletin》2017年第22期1547-1554,共8页Tingfeng Dou Cunde Xiao Zhiheng Du J. J. Schauer Hong Ren Baozhu Ge Aihong Xie Jihua Tan Pingqing Fu Yuanxun Zhang 
supported by the Ministry of Science and Technology of China(MOST, 2013CBA01804);the National Nature Science Foundation of China (41425003,41401079, 41476164 and 41625014);the key project of CAMS:Research on the Key Processes of Cryospheric Rapid Changes (KJZD-EW-G03);the Opening Founding of State Key Laboratory of Cryospheric Sciences(SKLCSOP-2016-03);the State Key Laboratory of Cryospheric Sciences (SKLCS-ZZ-2017)
Based on the field measurements in Barrow, Alaska within the period of April-May 2015, we investigate the sources and variations of elemental carbon(EC) and organic carbon(OC) in the surface layer of snowpack on sea i...
关键词：ARCTIC EC OC Sea ice ALBEDO BARROW 
Quantification of light-enhanced ionic transport in lead iodide perovskite thin films and its solar cell applications
《Light(Science & Applications)》2016年第1期120-127,共8页Yi-Cheng Zhao Wen-Ke Zhou Xu Zhou Kai-Hui Liu Da-Peng Yu Qing Zhao 
supported by the National 973 Project(2013CB932602,MOST);the Ministry of Science and Technology of China and the National Natural Science Foundation of China(NSFC51272007,61571015,11327902,11234001,91433102 and 51522201);the Beijing Nova Program(XX2013003);the Program for New Century Excellent Talents in University of China.
Ionic transport in organometal halide perovskites is of vital importance because it dominates anomalous phenomena in perovskite solar cells,from hysteresis to switchable photovoltaic effects.However,excited state ioni...
关键词：activation energy ion migration LIGHT PEROVSKITE 
Activated expression of At EDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis被引量：6
《Journal of Integrative Plant Biology》2015年第12期1017-1030,共14页Xiao-Teng Cai Ping Xu Yao Wang Cheng-Bin Xiang 
supported by grants from the Ministry of Science and Technology of China (MOST, 2012CB114304, 2011ZX08005-004);the Chinese Academy of Science (CAS, KSCX3-YW-N-007);the National Nature Science Foundation of China (NNSFC, 30830075, 90917004)
Root architecture is crucial for plants to absorb water and nutrients. We previously reported edtl （edtlD） mutant with altered root architecture that contributes significantly to drought resistance. However, the und...
关键词：EDT1/HDG11 jasmonic acid lateral root OPCL1 OPR3 
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