组蛋白H2A的变体H2A.Z在基因的表达过程中发挥着重要的作用。根据H2A.Z和H2A核小体中组蛋白甲基化修饰方式的不同,作者应用多样性增量二次判别方法(increment of diversity with quadratic discriminant,IDQD)成功地对H2A.Z和H2A核小体...
应用多样性增量结合二次判别分析(Increment of Diversity with Quadratic Discriminant analysis,IDQD)方法,对酵母基因组中的核小体强/弱偏好序列进行了识别。10交叉检验的预测成功率超过了97%,受试者操作特性(receiver operating cha...
supported by National Natural Science Foundation (No.90403010)
Topology of the transmembrane protein is closely related to its functions. So, it is desiderated to depict the topology of transmembrane proteins. In this work, an effective approach