This work was supported by National Natural Science Foundation of China (No. 30873108) and Natural Science Foundation of Shandong Province (No. Y2007C097).Acknowledgements: The first author of this article wants to express his special thanks to Professor WANG Kai of Department of Hepatology in Qilu Hospital of Shandong University for the suggestion and comments on experiments and manuscript. The author also thanks Qingdao University Guide for the Care and Use of Laboratory Animals for providing the animals.
Background Gingerol is the generic term for pungent constituents in ginger, which has been reported to be effective for inhibiting vomiting. We attempted to investigate the antiemetic effect of gingerol and its effect...