国家自然科学基金(10971068)

作品数：79被引量：204H指数：7
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A blockchain-based framework for data quality in edge-computing-enabled crowdsensing被引量：2
《Frontiers of Computer Science》2023年第4期127-139,共13页Jian AN Siyuan WU Xiaolin GUI Xin HE Xuejun ZHANG 
supported by the Key Science and Technology Project of Henan Province(201300210400);National Key Research and Development Project(2018YFB1800304);National Natural Science Foundation of China(61762058),Fundamental Research Funds for the Central Universities(xzy012020112);Natural Science Foundation of Gansu Province(21JR7RA282).
With the rapid development of mobile technology and smart devices,crowdsensing has shown its large potential to collect massive data.Considering the limitation of calculation power,edge computing is introduced to rele...
关键词：crowdsensing edge computing devices blockchain quality assessment reinforcement learning 
A SLC31A1-MEK-DNMT1-miR-124 feedback loop contributes to pancreatic cancer progression
《Genes & Diseases》2023年第3期654-656,共3页Jing Jin Mingjun Ma Bingru Yan Botao Qiu Shounan Lu Lin Yang Yuzhe Nie Sheng Tai Ze Yu Chun-Bo Teng 
supported by The National Natural Science Foundation of China(No.32072801);Fundamental Research Funds for the Central Universities of China(No.2572020DY12).
Although the role of copper (Cu) in promoting KRas- or BRaf-mutation driven cancers via activating MEK1/2 kinases is known, the mechanism by which the copper transporter SLC31A1 (CTR1) is upregulated in pancreatic can...
关键词：DNMT1 SLC treatment 
A patient with glycogen storage disease type IA combined with hepatic adenoma: A case report
《Genes & Diseases》2023年第3期701-704,共4页Maohui Yin Lei Chang Ping Jiang Zhiyong Yang Zhonglin Zhang Wanyu Zhang Zhisu Liu 
supported by the National Natural Science Foundation of China(NSFC,No.81702407/H1617);Fundamental Research Funds for the Central Universities of Ministry of Education of China(No.2042017kf0054);the Hubei Chenguang Talented Youth Development Foundation(HBCG),China.
Glycogen storage disease(GSD)is a rare autosomal recessive disease by abnormal accumulation of intracellular glycogen.1 Mutations in genes encoding G-6-P or G-6-Pase lead to dysfunction of the body's glycogen metaboli...
关键词：PATIENT ADENOMA HEPATIC 
Multivalent Display of Lipophilic DNA Binders for Dual-Selective Anti-Mycobacterium Peptidomimetics with Binary Mechanism of Action
《CCS Chemistry》2022年第11期3573-3586,共14页Jianxue Wang Junfeng Song Xianhui Chen Rey-Ting Guo Yingjie Wang Guopu Huang Nan Zheng Peilei Hu Xinxin Feng Yugang Bai 
This research was made possible as a result of the start-up funding from Hunan University,as a part of China’s Fundamental Research Funds for the Central Universities,the funding from the National Natural Science Foundation of China(grant nos.21877033,92163127,Y.B.,21807031,22177031,X.F.);the funding from the Natural Science Foundation of Hunan Province(grant no.2021JJ30088,Y.B.,2020JJ4177,X.F.);the Open Funding Project of the State Key Laboratory of Biocatalysis and Enzyme Engineering(Hubei University,SKLBEE2019003,X.F.).
We made oligoamidine-based peptidomimetics highly specific for mycobacteria eradication by introducing and arraying lipophilic DNA binding motifs on macromolecular backbones.The short poly(amidino-phenylindole)(PAPI)s...
关键词：PEPTIDOMIMETIC MYCOBACTERIA antimicrobial membrane disruption DNA binding 
Berberine inhibits the proliferation of pancreatic cancer cells by targeting pancreatic cancer stem cells through regulating EMT signaling pathway被引量：2
《BIOCELL》2022年第10期2257-2265,共9页MENGMENG LIU YUE PAN XUFENG TAO WENLI KANG YINGJIE LIU YONGJIE YANG GARY GUISHAN XIAO 
This research was supported by 81803024(National Natural Science Foundation of China)and DUT21LK23(Fundamental Research Funds for the Central Universities).
Pancreatic ductal adenocarcinoma(PDAC)is universally acknowledged as the cancer with the highest mortality rate.Berberine has high medicinal value and has been used as an anti-cancer agent.Hence the purpose of this st...
关键词：BERBERINE PDAC PCSCs EMT Antineoplasic 
Dendrite-free and anti-corrosion Zn metal anode enabled by an artificial layer for high-performance Zn ion capacitor被引量：3
《Chinese Chemical Letters》2022年第8期3936-3940,共5页Zhuo Li Zhe Gong Xiaoyu Wu Ke Ye Jun Yan Guiling Wang Yingjin Wei Kai Zhu Jin Yi Dianxue Cao Guohua Chen 
partially supported by Hong Kong Scholars Programs(No.XJ2019024);China Postdoctoral Science Foundation(Nos.2018M630340,2019T120254);Fundamental Research Funds for the Central Universities and National Natural Science Foundation of China(No.22075171)。
Aqueous zinc energy storage devices,holding various merits such as high specific capacity and low costs,have attracted extensive attention in recent years.Nevertheless,Zn metal anodes still suffer from a short lifespa...
关键词：Zn ion capacitor Aqueous electrolyte Surface structure Sn metal layer ANTI-CORROSION 
Chalcocite(bio)hydrometallurgy-current state,mechanism,and future directions:A review被引量：2
《Chinese Journal of Chemical Engineering》2022年第1期109-120,共12页Shichao Yu Rui Liao Baojun Yang Chaojun Fang Zhentang Wang Yuling Liu Baiqiang Wu Jun Wang Guanzhou Qiu 
supported by the National Natural Science Foundation of China(U1932129,51774332,51934009 and 52004086);Natural Science Foundation of Hunan Province(No.2018JJ1041),Fundamental Research Funds for the Central Universities of Central South University(Nos.2021zzts0301 and 2021zzts0299)。
There has been a strong interest in technologies suited for mining and processing of low-grade ores because of the rapid depletion of mineral resources in the world.In most cases,the extraction of copper from such raw...
关键词：CHALCOCITE BIOLEACHING Heap leaching KINETICS Copper sulfides HYDROMETALLURGY 
Lead and Iodide Fixation by Thiol Copper(Ⅱ)Porphyrin for Stable and Environmental-Friendly Perovskite Solar Cells被引量：6
《CCS Chemistry》2021年第10期25-36,共12页Guo-Bin Xiao Lu-Yao Wang Xi-Jiao Mu Xiao-Xin Zou Yi-Ying Wu Jing Cao 
National Natural Science Foundation of China(no.21801104)and Fundamental Research Funds for the Central Universities(no.lzujbky-2019-sp01).Y.-Y.W.acknowledges funding support from the U.S.Department of Energy(award no.DEFG02-07ER46427).The authors sincerely thank the theoretical calculation support of Prof.Penji Yan from Hexi University of China.
The formation of undersaturated lead or iodide ions and I_(2) on the perovskite surface can decrease the performance and stability of perovskite solar cells(PSCs).Additionally,the leakage of noxious lead limits the ap...
关键词：lead and iodide fixation thiol copper(II)porphyrin surface modulation environmental-friendly perovskite solar cells 
EnhFFL:A database of enhancer mediated feed-forward loops for human and mouse被引量：2
《Precision Clinical Medicine》2021年第2期129-135,共7页Ran Kang Zhengtang Tan Mei Lang Linqi Jin Yin Zhang Yiming Zhang Tailin Guo Zhiyun Guo 
The research was supported by the Basic Research Cultivation Support Programof Fundamental Research Funds for the Central Universities,the National Natural Science Foundation of China(Grant No.32071343);the Sichuan Science and Technology Program(Grant No.2021YJ0048).
Feed-forward loops(FFLs)are thought to be one of the most common and important classes of transcriptional network motifs involved in various diseases.Enhancers are cis-regulatory elements that positively regulate prot...
关键词：DATABASE ENHANCER miRNA transcription factor feed-forward loop 
Three-dimensional silk fibroin microsphere-nanofiber scaffolds for vascular tissue engineering
《Medicine in Novel Technology and Devices》2021年第1期52-59,共8页Qiang Liu Guoliang Ying Nan Jiang Ali KYetisen Danyu Yao Xiaoying Xie Yubo Fan Haifeng Liu 
This work was supported by the National Natural Science Foundation of China(31771058,32071359,11421202,61227902,and 11120101001);National Key Technology R&D Program(2016YFC1100704,2016YFC1101101);International Joint Research Center of Aerospace Biotechnology and Medical Engineering from Ministry of Science and Technology of China,111 Project(B13003);Research Fund for the Doctoral Program of Higher Education of China(20131102130004);Fundamental Research Funds for the Central Universities.G.L.Y.thanks Hubei Provincial Natural Science Foundation of China(No.2014CFB778).
A significant limitation in the engineering of artificial small-diameter vascular scaffolds is that the number of endothelial cells(ECs)is not sufficient to generate a confluent coverage of the vascular scaffolds,so t...
关键词：MICROFLUIDICS Silk fibroin ELECTROSPINNING MICRO/NANOSTRUCTURE Tissue engineering 
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