《Biophysics Reports》

作品数：280被引量：178H指数：5
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《Biophysics Reports》
主办单位：The Biophysical Society of China （BSC）
最新期次：2025年1期更多>>
发文主题：SINGLE-MOLECULEREPORTSBIOPHYSICSCA^(2+)IMAGING更多>>
发文领域：生物学医药卫生理学自动化与计算机技术更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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TRIM66-HP1γremodels the chromatin through phase separation
《Biophysics Reports》2025年第1期18-33,共16页Siyuan Shen Feng Chen Yifan Zhang Fudong Li Xuebiao Yao Dan Liu Yunyu Shi Liang Zhang 
supported by the National Natural Science Foundation of China(32090040,32293213,92149302 and 32470817);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB37010105 and XDB39010300);the Fundamental Research Funds for the Central Universities(WK9100000067)。
Chromatin contains not only heterochromatin(HC)and euchromatins(EC)but also facultative heterochromatin(f HC),which experience the dynamic remodeling between HCs and ECs by different regulators.The regulation of f HCs...
关键词：CHROMATIN TRIM66-HP1γ Facultative heterochromatin Phase separation 
Host cytoskeleton and membrane network remodeling in the regulation of viral replication
《Biophysics Reports》2025年第1期34-45,共12页Xuedi Gao Xinming Chen Letian Yu Shuangshuang Zhao Yaming Jiu 
Viral epidemics pose major threats to global health and economies.A hallmark of viral infection is the reshaping of host cell membranes and cytoskeletons to form organelle-like structures,known as viral factories,whic...
关键词：Viral replication factory Cytoskeleton Actin filaments MICROTUBULES Intermediate filaments Rearrangement of cellular membranes 
Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair
《Biophysics Reports》2025年第1期46-55,共10页Yuhao Jiang Chao Zhao Chenyang Zhang Weilin Li Di Liu Bailin Zhao 
supported by the National Natural Science Foundation of China(22104120);the Three Qin Talents Introduction Program for Youths of Shaanxi Province(2023SYJ26);the Fundamental Research Funds for the Central Universities(xtr052023008);the“Young Talent Support Plan”of Xi’an Jiaotong University to Bailin Zhao;by the National Natural Science Foundation of China(32400427);the China Postdoctoral Science Foundation(2022M712546);the Fundamental Research Funds for the Central Universities(xzy012023018);the Postdoctoral Research Project of Shaanxi Province(2023BSHEDZZ07)to Di Liu;by the Fundamental Research Funds for the Central Universities(xzy022024035)to Chenyang Zhang。
DNA double-strand breaks(DSBs)are the most severe form of DNA damage,primarily repaired by the non-homologous end joining(NHEJ)pathway.A critical step in this process is DNA synapsis,where the two broken ends are brou...
关键词：Single-molecule techniques smFRET Magnetic tweezers Non-homologous end joining(NHEJ) DNA Synapsis 
Advancements in proteogenomics for preclinical targeted cancer therapy research
《Biophysics Reports》2025年第1期56-76,共21页Yuying Suo Yuanli Song Yuqiu Wang Qian Liu Henry Rodriguez Hu Zhou 
financially supported by the National Key Research and Development Program(2022YFA1302902 to H.Z.);the Shanghai Municipal Science and Technology Major Project;supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0830000);the National Natural Science Foundation of China(22425703 to H.Z.)。
Advancements in molecular characterization technologies have accelerated targeted cancer therapy research at unprecedented resolution and dimensionality.Integrating comprehensive multi-omic molecular profiling of a tu...
关键词：PROTEOGENOMICS Targeted cancer therapy Integrated omics analysis 
Single-molecule tracking in living microbial cells
《Biophysics Reports》2025年第1期1-11,共11页Xiaomin Chen Qianhong Guo Jiexin Guan Lu Zhang Ting Jiang Liping Xie Jun Fan 
supported by the National Key Research and Development Program of China(2023YFC3402400);National Natural Science Foundation of China(32101049,32271271 and 62205048);the Sichuan Science&Technology Program(2023NSFSC0638);NHC Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital)(2021HYX007)。
Some microbes are referred to as model organisms because they are easy to study in the laboratory and hold the ability to retain their characteristics during DNA replication,DNA transcription,and other fundamental pro...
关键词：Single-molecule tracking PALM Diffusion coefficients TRAJECTORY Living microbial cells 
Features of the monocyte inflammatory response in patients with premature coronary artery disease
《Biophysics Reports》2025年第1期12-17,共6页Tatiana Blokhina Tatiana Kirichenko Yuliya Markina Ulyana Khovantseva Ivan Melnikov Olga Guseva Sergey Bazanovich Sergey Kozlov Alexander Orekhov 
supported by Russian Science Foundation(22-15-00134)。
The purpose of this study was to examine the secretion of inflammatory cytokines by cultured monocytes/macrophages in patients with premature coronary artery disease(CAD).The study included 38patients with premature C...
关键词：Coronary artery disease MONOCYTES Inflammatory cytokines Immune tolerance 
Special issue on“calcium signaling”
《Biophysics Reports》2024年第6期349-350,共2页Zong Jie Cui 
supported by a grant from the Natural Science Foundation of China(32271278)。
To commemorate the occasion of the establishment of The Section for Calcium Signaling in The Chinese Biophysics Society on 21 July 2023 in Changsha,Hunan Province,the editorial office of Biophysics Reports decided to ...
关键词：HUNAN EDITORIAL decided 
Characterization of auditory sensation in C.elegans
《Biophysics Reports》2024年第6期351-363,共13页Can Wang Elizabeth A.Ronan Adam J.Iliff Rawan Al-Ebidi Panagiota Kitsopoulos Karl Grosh Jianfeng Liu X.Z.Shawn Xu 
support from NIH T32 training grants;support from an NIH F32 grant;supported by grants from the NIDCD and NIGMS(to X.Z.S.X.)。
Research using the model organism nematode C.elegans has greatly facilitated our understanding of sensory biology,including touch,olfaction,taste,vision and proprioception.While hearing had long been considered to be ...
关键词：C.elegans HEARING AUDITION MECHANOSENSATION MECHANOSENSORY 
Drosophila melanogaster A rapid and reproducible method for generating germ-free
《Biophysics Reports》2024年第6期364-368,共5页An-Qi Li Sha-Sha Li Hui-Lin Li Lan-Lan Zhong Guo-Bao Tian Xin-Yuan Zhao Qiao-Ping Wang 
funded by the National Natural Science Foundation of China(31970934);the Fundamental Research Funds for the Central Universities(20ykzd18)to Q.P.W。
Microbial communities exert a profound influence on various facets of animal behavior and physiology,making the comprehension of their interactions with hosts or the environment essential.Drosophila melanogaster,a wid...
关键词：AXENIC GERM-FREE MICROBIOTA DROSOPHILA Protocol 
Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging
《Biophysics Reports》2024年第6期369-376,共8页Chenguang Yang Dongfei Ma Shuxin Hu Ming Li Ying Lu 
supported by the Guangdong Basic and Applied Basic Research Foundation(2020A1515110102);the National Natural Science Foundation of China(12022409 and T2221001);the CAS Key Research Program of Frontier Sciences(ZDBS-LY-SLH015)。
Membrane proteins often need to be inserted into or attached to the cell membrane to perform their functions.Understanding their transmembrane topology and conformational dynamics during insertion is crucial for eluci...
关键词：Membrane protein INSERT Real time Single molecule NANOSCALE 
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