《World Journal of Experimental Medicine》

作品数：208被引量：410H指数：10
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《World Journal of Experimental Medicine》
主办单位：百世登出版集团有限公司
最新期次：2025年2期更多>>
发文主题：CELLSOBESITYCANCERINFLAMMATIONBREAST_CANCER更多>>
发文领域：医药卫生自动化与计算机技术农业科学政治法律更多>>
发文基金：国家自然科学基金俄罗斯基础研究基金World Health Organization更多>>
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Establishment and characterization of a new human gallbladder cancer cell line,OCUG-2
《World Journal of Experimental Medicine》2025年第2期130-141,共12页Qiang Wang Canfeng Fan Gen Tsujio Takashi Sakuma Koji Maruo Yurie Yamamoto Daiki Imanishi Kyoka Kawabata Hinano Nishikubo Saki Kanei Rika Aoyama Syuhei Kushiyama Masaichi Ohira Masakazu Yashiro 
BACKGROUND Gallbladder cancer(GBC)is a highly aggressive malignant tumor originating from the biliary tract.As one of the most common malignancies in the biliary system,GBC is particularly challenging due to its tende...
关键词：Gallbladder cancer Cell line Insulin-like growth factor 1 receptor Molecular target Mouse model 
miRNA dysregulation in Duchenne muscular dystrophy comorbidities
《World Journal of Experimental Medicine》2025年第2期142-149,共8页Subhashree Sivakumar Archana Rajavel Venkataraman Viswanathan Evangeline Ann Daniel Prakash Gangadaran Raja Natesan Sella 
BACKGROUND Duchenne muscular dystrophy(DMD)is a neuromuscular disorder caused by mutations in the dystrophin gene.DMD is reported to coexist with other comorbidities,although the occurrence of the triad,autism spectru...
关键词：Duchenne muscular dystrophy DYSTROPHIN MIRNA Autism spectrum disorder Phosphatase and tensin Inflammatory response 
Cytoplasmic and nuclear programmed death ligand 1 expression in peritumoral stromal cells in breast cancer:Prognostic and predictive value
《World Journal of Experimental Medicine》2025年第2期150-170,共21页Evgeniya Yu Zubareva Marina A Senchukova Natalia V Saidler 
Supported by Russian Science Foundation,No.23-25-00183.
BACKGROUND Breast cancer(BC)continues to occupy a leading position in terms of morbidity and mortality from malignant neoplasms among the female population.One of the promising markers associated with BC progression i...
关键词：Breast cancer Programmed death-ligand 1 Regional metastasis Tumor stroma 
Matrix metalloproteinases and their tissue inhibitors as indicators of aortic aneurysm and dissection development in extracellular matrix remodeling
《World Journal of Experimental Medicine》2025年第2期1-11,共11页Marc Irqsusi Fiona R Rodepeter Madeline Günther Andreas Kirschbaum Sebastian Vogt 
Aneurysms and dissections represent some of the most serious cardiovascular diseases.The prevailing theory posits that mechanical overloading of the vessel wall is the underlying cause.Inspired by Barkhordarian et al,...
关键词：Matrix metalloproteinases Tissue inhibitor of metalloproteinases Acute aortic dissection Aortic aneurysm Extracellular matrix remodeling PATHOGENESIS 
Biomarkers for tracking metabolic changes pre-post nutritional epigenetics diet/intervention to prevent autism and attention deficit/hyperactivity disorders in children
《World Journal of Experimental Medicine》2025年第2期12-23,共12页Renee J Dufault 
The prevalence of autism and attention deficit/hyperactivity disorders is increasing worldwide.Recent studies suggest the excessive intake of ultra-processed food plays a role in the inheritance of these disorders via...
关键词：Mercury Lead AUTISM Attention deficit/hyperactivity disorder METALLOTHIONEIN Nutritional epigenetics Zinc 
Dynamics of inflammatory signals within the tumor microenvironment
《World Journal of Experimental Medicine》2025年第2期24-39,共16页Hala Issa Lokjan Singh Kok-Song Lai Tina Parusheva-Borsitzky Shamshul Ansari 
Tumor stroma,or tumor microenvironment(TME),has been in the spotlight during recent years for its role in tumor development,growth,and metastasis.It consists of a myriad of elements,including tumor-associated macropha...
关键词：Inflammatory signals Tumor microenvironment CYTOKINES INTERLEUKINS Transforming growth factor 
Integrative review of the gut microbiome’s role in pain management for orthopaedic conditions
《World Journal of Experimental Medicine》2025年第2期40-50,共11页Naveen Jeyaraman Madhan Jeyaraman Priya Dhanpal Swaminathan Ramasubramanian Arulkumar Nallakumarasamy Sathish Muthu Gabriel Silva Santos Lucas Furtado da Fonseca JoséFábio Lana 
The gut microbiome,a complex ecosystem of microorganisms,has a significant role in modulating pain,particularly within orthopaedic conditions.Its impact on immune and neurological functions is underscored by the gut-b...
关键词：Gut microbiome Pain management ORTHOPAEDICS Gut-brain axis PROBIOTICS Inflammation 
Immunomodulatory effect of allium sativum in type 2 diabetes mellitus
《World Journal of Experimental Medicine》2025年第2期51-62,共12页Elva Manuela Mejía Delgado Juan Eduardo Quiroz-Aldave María del Carmen Durand-Vásquez Lea NoemíAldave-Pita Jenyfer María Fuentes-Mendoza Luis Alberto Concepción-Urteaga JoséPaz-Ibarra Marcio JoséConcepción-Zavaleta 
Type 2 diabetes mellitus(T2DM)is a metabolic disorder marked by chronic hyperglycemia and low-grade inflammation,contributing to various complications.Natural agents with immunomodulatory and antioxidant properties ha...
关键词：GARLIC PHYTOTHERAPY Anti-inflammatory agents ANTIOXIDANTS Immunomodulating agents Type 2 diabetes mellitus 
Diarylpentanoid,a curcumin analog,inhibits malignant meningioma growth in both in vitro and in vivo models
《World Journal of Experimental Medicine》2025年第2期171-184,共14页Anna Terasawa Kazuhiro Shimazu Hiroshi Nanjo Masatomo Miura Hiroyuki Shibata 
Supported by TAIHO Pharmaceutical,No.AS2023A000122715;Nippon Kayaku,No.NKCS20230416001.
BACKGROUND Malignant meningioma metastasizes systemically,primarily due to its role in epithelial-mesenchymal transition.Although the prognosis is extremely poor,drug development efforts have been limited,because this...
关键词：Malignant meningioma CURCUMIN Diarylpentanoid curcumin analog Hepatocellular growth factor Nuclear factor kappa B N-CADHERIN 
Anti-hypertensive effect of enriched white melon seed protein concentrate biscuit on sodium fluoride exposed rats
《World Journal of Experimental Medicine》2025年第2期185-199,共15页Olamide Wilson Fasakin Ayoola Awosika Sanmi Tunde Ogunsanya Iyanuoluwa Olushola Benson Akinyode Isaac Olopoda 
Sodium fluoride(NaF)is a daily necessity consumed as the major ingredient of fluorinated drinking water,milk,salts,mouthwashes,toothpaste,and dentistry medications.However,the use of NaF products has also been associa...
关键词：HYPERTENSION Sodium fluoride Sweet orange peels White melon seed Protein concentrate 
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