《Journal of Hainan Medical University》

作品数:3042被引量:336H指数:3
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《Journal of Hainan Medical University》
主办单位:Hainan Medical University
最新期次:2024年4期更多>>
发文主题:INFLAMMATORYTREATMENTINVASIONMETA-ANALYSISMECHANISM更多>>
发文领域:医药卫生自动化与计算机技术经济管理理学更多>>
发文基金:国家自然科学基金广西壮族自治区自然科学基金北京市自然科学基金湖北省自然科学基金更多>>
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Exploring the effect of Bushen Bitong recipe-containing serum on IL-1β-induced chondrocyte apoptosis based on SOX9/NF-κB/MMP-13 signaling pathway
《Journal of Hainan Medical University》2024年第4期1-7,共7页YI Lin ZHANG Wen-hao XIANG Wen-yuan SHI Zheng-yu REMILA Aimai-ti DENG Ying-jie FANG Rui 
National Natural Science Foundation of China(No.82360934);Science and Technology Innovation Leading Talents Project of Xinjiang Uygur Autonomous Region(No.2022TSYCLJ0007);Xinjiang Uygur Autonomous Region Key Research and Development Task Special Project(No.2021B03006);Natural Science Foundat ion of Xinj iang Uygur Autonomous Region(No.2022D01C170,2022D01C171)。
Objective:To observe the effect and possible mechanism of action of Bushen Bitong recipe(BSBT)containing serum on IL-1β-induced chondrocyte apoptosis.Methods:Generation 3 rat chondrocytes were randomized into Control...
关键词:Bushen Bitong recipe Osteoarthritis CHONDROCYTES Signaling pathway IL-1Β 
Effects of Yigan Capsule on the expression of HMGB1,RAGE and NF-κB protein in rats with drug-induced liver injury
《Journal of Hainan Medical University》2024年第4期8-14,共7页TANG Ya LI Jun QI Yazhi CAO Rui ZHAI Yan-ling HAN Yu-sheng XU Qiang 
Scientific Research Project of Heilongjiang Provincial Education Department(No.12531608)。
Objective:To study the effect of Yigan capsule on the expression of high mobility group protein B1(HMGB1),nuclear factor-B(NF-κB)and receptor for advanced glycation end products(RAGE)in anti-tuberculosis drug-induced...
关键词:Yigan capsule Anti-tuberculosis drug-induced liver INJURY HMGB1 RAGE NF-κB 
Prostaglandin D2 regulation of autophagy affects stemness of gastric cancer stem cells
《Journal of Hainan Medical University》2024年第4期15-21,共7页TIAN Heng-jin WANG Fei-fan GAO Peiyao CHEN Amin WANG Na ZHANG Qiang 
Natural Science Foundation of Anhui Province(No.1908085MH258);Scientific Research and Innovation Project of Bengbu Medical College(No.Byycxz21004)。
Objective:To explore the effect and mechanism of prostaglandins D2(PGD2)on the stemness of gastric cancer stem cells(GCSCs).Methods:7901-GCSCs were enriched by serum-free culture method;then the positivity rate of CD4...
关键词:PGD2 Gastric cancer Gastric cancer stem cells AUTOPHAGY STEMNESS 
Prognostic characterization of copper death-related immune checkpoint genes and analysis of immunologic and pharmacologic therapy in bladder cancer
《Journal of Hainan Medical University》2024年第4期22-22,共1页YANG Cong-yu A Runa LIU Jia-ming 
Key Research Project of Sichuan Provincial Department of Science and Technology(No.23ZDYF1246)。
Objective:Copper death-induced tumor cell death and immune checkpoint blockade therapy are highly selective.Combining their advantages and understanding their characteristics in bladder cancer is very important for th...
关键词:Bladder cancer Copper death Immune checkpoints Immunotherapy Drug therapy 
Analysis of clinical characteristics of leptomeningeal metastasis with band-like high signal in the brainstem
《Journal of Hainan Medical University》2024年第4期23-28,共6页LIN Hui-xia LIU Ting YANG Yi-hao LI Fei LIANG Bin-ji LI Li-juan LI Zhi-qun LI Qifu 
Hainan Clinical Medical Center Construction Project(2021);Excellent Talent Team of Hainan Province(No.QRCBT202121);Key R&D Program of Hainan Province(No.ZDYF2022SHFZ109)。
Objective:The aim was to analyse the clinical features of leptomeningeal metastasis with banded high signal in the brainstem.Methods:In this paper,we report two cases of lung adenocarcinoma with soft meningeal metasta...
关键词:Leptomeningeal metastasis Band-like high signal Lung adenocarcinoma Magnetic resonance imaging Ce-rebrospinal fluid Blood-brain barrier 
Sequential experimental observation on the curative effect of Yingbupu decoction of Zhuang medicine on stage I and II acute kidney injury
《Journal of Hainan Medical University》2024年第4期29-36,共8页ZHOU Yan HUANG Guo-dong XIE Zhang-qing ZHOU Chang-yan LIANG Jing-yan LUO Jia 
2021 Guangxi Famous Traditional Chinese Medicine Inheritance Studio Construction Project[Guizhong Medicine Science and Education Development(2021)No.6];Key Discipline of Personnel Training-Ethnic Medicine(Zhuang Medicine)(050220250102);Graduate Student Innovation and Entrepreneurship Project of Guangxi University of Traditional Chinese Medicine in 2021(YCXJ2021125)。
Objective:To observe the clinical efficacy of the Zhuang medicine Yingbupu decoction on stage I and II acute kidney injury through sequential test.Methods:The open one-way qualitative response sequential design of exp...
关键词:Zhuang medicine Yingbupu decoction Acute kidney injury Sequential test 
To explore the mechanism of Fuyang Jiebiao granules against viral pneumonia based on network pharmacology and pharmacodynamics
《Journal of Hainan Medical University》2024年第4期37-46,共10页TAN Dan-dan FENG Zhenyu MENG Shuang WANG Xuyan WANG Xin-xin ZHAO Jie ZHAO Jian-ping 
Emergency Research Project for Novel Coronavirus(2019-nCoV)Prevention and Control in Shanxi Province(No.202003D31012/GZ);Jingfang Fuyang Key Laboratory of Shanxi Province(No.202104010910011);Shanxi Provincial Health Commission Key Laboratory Construction Project。
Objective:To investigate the mechanism of Fuyang Jiebiao granule(FYJBKL)in the treatment of viral pneumonia.Methods:Firstly,a network model was constructed using network pharmacology to study the target expression sit...
关键词:FYJBKL granule Network pharmacology PHARMACODYNAMICS Viral pneumonia Molecular docking Jing-fang Fuyang 
Meta-analysis of the efficacy and safety of Bushen Huoxue decoction in the treatment of Osteoporosis
《Journal of Hainan Medical University》2024年第4期47-53,共7页LI Kai-ming JIA Yi-xuan SUN Jian-feng SHEN Yang-yong REN Gui-ju CAI Tongchuan ZHANG Qing SUN Shu-chun CHONG Hui 
National Natural Science Foundation Project of China(No.81904230,82205155);Capital Health Development Research Project(No.2018-2-4162)。
Objective:To systematically evaluate the long-term efficacy of Bushen Huoxue Decoction combined with vertebroplasty(PVP or PKP)in the treatment of osteoporotic vertebral compression fractures(OVCF),in order to provide...
关键词:Bushen Huoxue decoction OVCF EFFECT META-ANALYSIS RCT 
Research progress on dynamic monitoring of ctDNA and drug resistance related concomitant mutations in non-small cell lung cancer
《Journal of Hainan Medical University》2024年第4期54-54,共1页XUE Chong-xiang ZHANG Xu LU Xing-yu CUI Hui-juan 
National Natural Science Foundation of China(No.81873396);Capital Health Development Research Project(No.2018-2-4065);Project of China-Japan Friendship Hospital(No.2018-HX-26)。
Owing to significantly prolonged survival,targeted therapy has become standardized recommendation for advanced non-small cell lung cancer patients with mutated driver genes.However,the genetic status of lung cancer pa...
关键词:Non-small cell lung cancer CTDNA Targeted therapy Concomitant mutations Research progress 
Advances of lncRNA MAFG-AS1 in cancer
《Journal of Hainan Medical University》2024年第4期55-59,共5页LI Bing TIAN Yuan-yuan SUN Xiao-ning WANG Jiao 
Hainan Province Higher Education Science Research Project(No.Hnky2020ZD-15)。
In recent years,with the development of medical technology,the detection rate of cancer is getting higher and higher,and the population of patients is getting younger.Many studies have begun to study the early diagnos...
关键词:CANCER LncRNA MAFG-AS1 DIAGNOSIS PROGNOSIS Drug resistance 
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