《Genes & Diseases》

作品数：1386被引量：2487H指数：20
导出分析报告
《Genes & Diseases》
主办单位：Chongqing Medical University
最新期次：2025年3期更多>>
发文主题：CANCERMETABOLISMMETASTASISPROMOTESHEPATOCELLULAR_CARCINOMA更多>>
发文领域：医药卫生生物学文化科学理学更多>>
发文基金：国家自然科学基金重庆市自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
HMGN2 accelerates the proliferation and cell cycle progression of glioblastoma by regulating CDC20 expression
《Genes & Diseases》2025年第3期492-507,共16页Jiacheng Zhong Shuang Shi Wen Peng Hongjuan Cui Xiaochuan Sun 
Gliomas represent the most common primary malignant intracranial tumors in adults.Despite recent advances in treatment,the prognosis of patients with glioblastoma remains poor.Epigenetic abnormalities,the hallmarks of...
关键词：CDC20 Epigenetic regulation GLIOMA Histone acetylation HMGN2 
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization
《Genes & Diseases》2025年第3期508-522,共15页Huijun Qiu Jiang Liu Jingyi You Ou Zhou Chang Hao Yi Shu Deyu Ma Wenjing Zou Linghuan Zhang Enmei Liu Zhengxiu Luo Luo Ren Gang Geng Lin Zou Danyi Peng Zhou Fu 
supported by the General Basic Research Project from the Ministry of Education Key Laboratory of Child Development and Disorders(China)(No.GBRP202115);the Chongqing Science and Technology Bureau Major Project(China)(No.cstc2020jcyj-msxmX0782).
Pulmonary fibrosis is a devastating lung disease without effective treatment options. Sphingosine-1-phosphate receptor 3 (S1pr3), a receptor for the lipid signaling moleculesphingosine-1-phosphate, has been shown to m...
关键词：BLEOMYCIN IL-4 M2 polarization MACROPHAGE Pulmonary fibrosis S1pr3 
The genomic and epigenomic landscape of iridocorneal endothelial syndrome
《Genes & Diseases》2025年第3期523-532,共10页Yaoming Liu Gen Li Jiaxuan Jiang Sujie Fan Lan Lu Ting Wang Guigang Li Wenzong Zhou Xuequn Liu Yingjie Li Hong Sun Liang Liang Yuhong Tang Yang Chen Jianjun Gu Fei Li Xiuli Fang Tao Sun Aiguo Lv Yayi Wang Peiyuan Wang Tao Wen Jiayu Deng Yuhong Liu Mingying Lai Jingni Yu Danyan Liu Hua Wang Meizhu Chen Li Li Xiaodan Huang Jingming Shi Xu Zhang Kang Zhang Lingyi Liang Xiulan Zhang 
supported by the National Key Research and Development Program of China(No.2022YFC2502800);the National Natural Science Foundation of China(No.82070955,32000537).
Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding eye diseasewith an unknown etiology. Understanding its genomic and epigenomic landscape could aid indeveloping etiology-based therapies. In this...
关键词：Copy number variance DNA methylation ETIOLOGY Iridocorneal endothelial syndrome Whole-genome sequencing 
Mitochondrial SLC3A1 regulates sexual dimorphism in cystinuria
《Genes & Diseases》2025年第3期533-549,共17页Jingyi Su Yongdong Pan Fengbo Zhong Yi Zhong Jiaxin Huang Shengnan Liu Kaiyuan Wang Kai Lin Xiangchen Gu Dali Li Qihui Wu Hongquan Geng Yuting Guan Guofeng Xu 
supported by grants from the Science and Technology Commission of Shanghai Municipality of China(No.23Y21900102 to G.X.;23ZR1467900 to Q.W.);Shanghai Rising-Star Program(No.22QA1405900 to Y.G.);the National Key R&D Program of China(No.2022YFC2505400,2022YFC3400203 to Y.G.);the National Natural Science Foundation of China(No.82100773 to Y.G.;82101486,82371426 to Q.W.);the Natural Science Foundation of Chongqing,China(No.CSTB2022NSCQ-MSX1621 to Y.G.);the Ningxia Hui Autonomous Region Key Research and Development Project(China)(No.2022BFH02012 to Q.W.).
Cystinuria is the most common inheritable cause of kidney stone disease,with males exhibiting a higher susceptibility than females.However,the cellular origin and underlying mechanisms of sex differences in cystinuria...
关键词：CYSTINURIA Kidney injury MITOCHONDRIA Sex bias Slc3a1 
YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response
《Genes & Diseases》2025年第3期550-566,共17页Hao Li Kailun Yu Xiandan Zhang Jiawen Li Huilong Hu Xusheng Deng Siyu Zeng Xiaoning Dong Junru Zhao Yongyou Zhang 
supported by grants from the National Natural Science Foundation of China(No.81772539,81972238);the Fundamental Research Funds for the Central Universities of China-Xiamen University(No.20720180048).
Severe immune responses regulate the various clinical hepatic injuries, includingautoimmune hepatitis and acute viral hepatitis. N6-methyladenosine (m6A) modification is acrucial regulator of immunity and inflammation...
关键词：Concanavalin A HEPATITIS Inflammatory response N6-methyladenine YTHDF1 
Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cells
《Genes & Diseases》2025年第3期567-583,共17页Jing Zou Chengcheng Du Senrui Liu Piao Zhao Shengqiang Gao Bowen Chen Xiangdong Wu Wei Huang Zhenglin Zhu Junyi Liao 
supported by the Science and Technology Research Program of the Chongqing Education Commission(China)(No.KJQN202100431,KJZDM202100401);supported by the National Natural Science Foundation of China(No.81972069,82002312);CQMU Program for Youth Innovation in Future Medicine(Chongqing,China)(No.W0154);Innovation Project from Chongqing Municipal Education Commission(China)(No.CYB21169);Cultivating Program and Candidate of TipTop Talent of The First Affiliated Hospital of Chongqing Medical University(Chongqing,China)(No.BJRC2021-04);Cultivating Program of Postdoctoral Research of The First Affiliated Hospital of Chongqing Medical University(Chongqing,China)(No.CYYY-BSHPYXM-202202);Special Support from Chongqing Postdoctoral Research Program(Chongqing,China)(No.2021XM1029);upported by a postdoctoral fellowship from Chongqing Medical University and rewarded by China Postdoctoral Science Foundation(No.2022M720605).
Although bone morphogenetic protein 2 (BMP2) can induce chondrogenic differentiation of mesenchymal stem cells (MSCs), its induction of endochondral ossification limits theapplication of BMP2-based cartilage regenerat...
关键词：BMP2 Chondrogenic differentiation Endochondral ossification Mesenchymal stem cells Notch1 signaling 
IRF8 aggravates nonalcoholic fatty liver disease via BMAL1/PPARγ axis
《Genes & Diseases》2025年第3期584-598,共15页Xinyue Li Hong Zhang Fan Yu Shuting Xie Tongyu Wang Rong Zhang Guangzhong Xu Liang Wang Yeping Huang Cheng Hu 
supported by grants from the National Science Foundation of China(No.81974118,82325010);The Shanghai Outstanding Academic Leaders(China)(No.20XD1433300);the Shuguang Project of China(21SG11);the Innovative Research Team of High-level Local Universities in Shanghai,China(No.SHSMU-ZDCX20212700);the Major Natural Science Project of the Scientific Research and Innovation Plan of Shanghai Municipal Commission of Education(China)(No.2023ZKZD17);the Shanghai Research Center for Endocrine and Metabolic Diseases(China)(No.2022ZZ01002);the Shanghai Sixth People’s Hospital Foundation(China)(No.ynqn202105).
Non-alcoholic fatty liver disease(NAFLD)is a hepatic metabolic syndrome arisingfrom lipid metabolic imbalance,with its prevalence increasing globally.In this study,weobserved a significant up-regulation of interferon ...
关键词：Brain and muscle ARNT-Like 1 Hepatic steatosis Interferon regulatory factor 8 LIPOGENESIS Non-alcoholic fatty liver disease Peroxisome proliferator-activated receptorγ Transcriptional regulation 
Landscape of chimeric RNAs in COVID-19 patient blood
《Genes & Diseases》2025年第3期599-610,共12页Samuel Haddox Ping Wu Sandeep Singh Fujun Qin Jack Engel Andrea Kian Syed Ahmad Hui Li Peng Wu 
supported by the National Institutes of Health(USA)(No.R01GM132138 to H.L.).
Despite the availability of efficacious vaccines, COVID-19 persists and our knowledge of how SARS-CoV-2 infection affects host transcriptomics remains incomplete. Transcriptome analysis, which has progressed our under...
关键词：BLOOD Chimeric RNA COVID-19 PTBP1 SARS-CoV-2 
A novel research model of clonal evolution in mantle cell lymphoma at the single-cell genomic level
《Genes & Diseases》2025年第3期35-38,共4页Li Zhang Yongsheng Liu Liang Wang Li Wang Li Zheng Wei He Li Yan Lvsu Ye Huidan Zhang Junling Tang 
funded by the Chongqing Medical Scientific Research Project(Joint Project of Chongqing Health Commission and Science and Technology Bureau,China)(No.2023GGXM006,2024ZDXM026,2024MSXM115);the Key Research Project from Science and Technology Department of Sichuan Province,China(No.2019YFS0301);the Chongqing Key Municipal Public Health Specialty Construction Project(China);the Key Research Project from Chongqing Medical and Pharmaceutical Vocational Education Group(China)(No.CQZJ202329);the Incubation Project of the First Affiliated Hospital of Chongqing Medical and Pharmaceutical College(China)(No.2022-2023ZD04,2022-2023ZD03,2022-2023MS04,2022-2023MS03,2022-2023MS010);the Science and Technology Research Program of Chongqing Education Commission(China)(No.KJQN202302811).
Mantle cell lymphoma(MCL)is recognized as one of the most genetically heterogeneous diseases,with high instability at the genomic level.MCL is common in males with a male-to-female ratio of about 2:1,and its incidence...
关键词：hematopoietic lineage mantle cell lymphoma mcl clonal evolution genomic instability tumor immunity evolution tree single cell genomic level genetic heterogeneity mantle cell lymphoma 
Utilization of cuproptosis-related lncRNAs to predict the prognosis of pancreatic cancer patients and explore their roles in immune cell infiltration and prognosis evaluation
《Genes & Diseases》2025年第3期39-41,共3页Kaili Liao Jinting Cheng Xiajing Yu Ziqian Liu Xue Zhang Yuxin Fu Wenyige Zhang Jie Liu Feifei Teng Yuxuan Xie Xiwen Yan Gaoquan Cao Bing Sun Hanqing Zhao Jingyan Zhang Xiaozhong Wang 
funded by the National Natural Science Foundation of China(No.82160405).
The prognosis of pancreatic cancer(PC)is difficult to predict1 and is extremely poor.2 Studies showed that cuproptosis was related to PC.The roles are not completely understood.It is considered that lncRNAs are closel...
关键词：pearson correlation analysis immune cell infiltration univariate cox regression analysis lncRNAs cuproptosis pancreatic cancer pancreatic cancer pc PROGNOSIS 
全选清除导出
共139页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部