《Engineering Microbiology》

作品数：109被引量：51H指数：4
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《Engineering Microbiology》
主办单位：山东大学
最新期次：2024年4期更多>>
发文主题：METABOLIC_ENGINEERINGBIOSYNTHESISSACCHAROMYCES_CEREVISIAEMICROBIALRECOMBINEERING更多>>
发文领域：生物学理学医药卫生经济管理更多>>
发文基金：国家自然科学基金高等学校学科创新引智计划上海市浦江人才计划项目中国博士后科学基金更多>>
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Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose
《Engineering Microbiology》2024年第4期1-11,共11页Wei Ma Shiyu Yuan Zixian Wang Kangle Niu Fengyi Li Lulu Liu Lijuan Han Xu Fang 
This work was supported by National Key R&D Program of China(No.2018YFA0901700);National Natural Science Foundation of China(No.32271526).
This research identified four amino acid residues(Leu174,Asn297,Tyr301,and Gln291)that contribute to sub-strate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei.Potential hotspots af...
关键词：Hexose transporter GLUCOSE GALACTOSE MANNOSE Transmembrane α-helix 7 Sugar transport Computer-aided screening 
Functional analysis of the whole CYPome and Fdxome of Streptomyces venezuelae ATCC 15439
《Engineering Microbiology》2024年第4期12-23,共12页Shuai Li Zhong Li Guoqiang Zhang Vlada BUrlacher Li Ma Shengying Li 
This work was supported by the National Natural Science Foundation of China(32025001,32071266 and 32200017);the Shandong Provin-cial Natural Science Foundation(ZR2022QC070 and ZR2019ZD20).
Cytochrome P450 enzymes(CYPs or P450s)and ferredoxins(Fdxs)are ubiquitously distributed in all domains of life.Bacterial P450s are capable of catalyzing various oxidative reactions with two electrons usually donated b...
关键词：STREPTOMYCES Cytochrome P450 enzymes CYPome FERREDOXIN Fdxome PikC 
Proactive monitoring of changes in the microbial community structure in wastewater treatment bioreactors using phospholipid fatty acid analysis
《Engineering Microbiology》2024年第4期24-32,共9页Lawson Mensah Elise Cartmell Mandy Fletton Mark Scrimshaw Pablo Campo 
Diverse microbial community structures(MCS)in wastewater treatment plants(WWTPs)are vital for effectively removing nutrients and chemicals from wastewater.However,the regular monitoring of MCS in WWTP bioreac-tors rem...
关键词：Phospholipids fatty acid analysis Microbial community structure Solids and hydraulic retention times Temperature Bioreactor health Activated sludge 
Immobilization of Thermomyces lanuginosus lipase on metal-organic frameworks and investigation of their catalytic properties and stability
《Engineering Microbiology》2024年第4期33-43,共11页Zeynab Rangraz Mostafa M.Amini Zohreh Habibi 
Surface adsorption is a convenient and readily available method for immobilizing enzymes on metal-organic frameworks(MOFs).Metal-organic framework-5(MOF-5),isoreticular metal-organic frameworks-3(IRMOF-3),and multivar...
关键词：BIOCATALYST MOF Enzyme immobilization LIPASE THIAZOLES 
Genetically engineered bacteria as inflammatory bowel disease therapeutics
《Engineering Microbiology》2024年第4期44-55,共12页Zhen-Ping Zou Xiao-Peng Zhang Qian Zhang Bin-Cheng Yin Ying Zhou Bang-Ce Ye 
This work was sponsored by the National Key Research and Devel-opment Program of China(2023YFF1204500);the National Natural Sci-ence Foundation of China(22134003);China Postdoctoral Science Foundation(2023M741176).
Inflammatory bowel disease(IBD)is a chronic and recurrent disease caused by immune response disorders that disrupt the intestinal lumen symbiotic ecosystem and dysregulate mucosal immune functions.Current therapies av...
关键词：Genetically engineered bacteria Inflammatory bowel disease Bacterial therapeutics 
Biofuel production from lignocellulose via thermophile-based consolidated bioprocessing
《Engineering Microbiology》2024年第4期56-64,共9页Yilin Le Mengqi Zhang Pengju Wu Huilei Wang Jinfeng Ni 
This work was supported by the Natural Science Foundation of Jiangsu Province,China(Grant NO.BK20231326);National Key R&D Program of China(2020YFA0906800);State Key Laboratory of Micro-bial Technology Open Projects Fund(Project NO.M2022-10).
The depletion of fossil fuels and their impact on the environment have led to efforts to develop alternative sustainable fuels.While biofuel derived from lignocellulose is considered a sustainable,renewable,and green ...
关键词：LIGNOCELLULOSE BIOFUEL Consolidated bioprocessing THERMOPHILE Thermophilic enzymes 
Exploring interspecific interaction variability in microbiota: A review
《Engineering Microbiology》2024年第4期65-78,共14页Zhong Yu Zhihao Gan Ahmed Tawfik Fangang Meng 
This work was supported by the National Natural Science Foundation of China(32161143031 and 52300072).
Interspecific interactions are an important component and a strong selective force in microbial communities.Over the past few decades,there has been a growing awareness of the variability in microbial interactions,and...
关键词：Microbial community Interspecific interaction Interaction variability Variability mechanism Interaction characterization 
The way to uncovering and utilizing marine microbial resources
《Engineering Microbiology》2024年第4期79-81,共3页Zhi-Feng Zhang Meng Li 
This work was financially supported by the National Key Re-search and Development Program of China(2022YFA0912200);Na-tional Natural Science Foundation of China(32225003,32393970,32393971);Guangdong Major Project of Basic and Applied Basic Re-search(2023B0303000017);Shenzhen Medical Research Fund(no.B2301005);Shenzhen University 2035 Program for Excellent Research(2022B002);research funds from Key Laboratory of Marine Micro-biome Engineering of Guangdong Higher Education Institutes and the Synthetic Biology Research Center of Shenzhen University.
Recently,Chen et al.published their breakthrough results on a marine microbial genomic catalog and genetic potentials in bioprospecting in Nature,providing unprecedented opportunities for development and utilization o...
关键词：METAGENOME MAG Global ocean microbiome genome catalogue CRISPR-Cas9 Antimicrobial peptide PETases 
CRISPR-Cas9-based genome-editing technologies in engineering bacteria for the production of plant-derived terpenoids
《Engineering Microbiology》2024年第3期43-53,共11页Xin Sun Haobin Zhang Yuping Jia Jingyi Li Meirong Jia 
supported by the Beijing Nova Program (Z211100002121004);CAMS Innovation Fund for Medical Sci-ences (CIFMS 2021-I2M-1-029,CIFMS 2022-I2M-2-002);Nonprofit Central Research Institute Fund of the Chinese Academy of Medical Sciences (2021-RC350-003).
Terpenoids are widely used as medicines,flavors,and biofuels.However,the use of these natural products is largely restricted by their low abundance in native plants.Fortunately,heterologous biosynthesis of terpenoids ...
关键词：CRISPR-Cas9 Genome editing TERPENOIDS Metabolic engineering BACTERIA 
Mechanisms of tigecycline resistance in Gram-negative bacteria:A narrative review被引量：1
《Engineering Microbiology》2024年第3期54-61,共8页Wenya Su Wenjia Wang Ling Li Mengge Zhang Hai Xu Chengzhang Fu Xiuhua Pang Mingyu Wang 
supported by the National Key Research and De-velopment Program of China[grant number 2022YFE0199800];Key R&D Program of Shandong Province[grant number 2020CXGC011305];Shandong Provincial Natural Science Foundation[grant number ZR2020MH308];the National Natural Science Foundation of China[grant number 82,271,658].
Tigecycline serves as a critical“final-resort”antibiotic for treating bacterial infections caused by multidrug-resistant bacteria for which treatment options are severely limited.The increasing prevalence of tigecyc...
关键词：Gram-negative bacteria TIGECYCLINE Tigecycline resistance Resistance mechanisms RND efflux pump 
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