《Acta Biochimica et Biophysica Sinica》

作品数：5120被引量：17699H指数：35
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《Acta Biochimica et Biophysica Sinica》
主办单位：International Association for Biological & Medical Research （IABMR）
最新期次：2025年2期更多>>
发文主题：APOPTOSISPROMOTESPROLIFERATIONEXPRESSION英文更多>>
发文领域：生物学医药卫生农业科学化学工程更多>>
发文作者：吴祥甫李伯良刘新垣丁达夫周元聪更多>>
发文机构：中国科学院上海生命科学研究院中国科学院复旦大学上海医科大学更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
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Corrigendum to:Downregulating integrin subunit alpha 7(ITGA7)promotes proliferation,invasion,and migration of papillary thyroid carcinoma cells through regulating epithelial-to-mesenchymal transition
《Acta Biochimica et Biophysica Sinica》2025年第2期325-325,共1页Yaoyao Guan Adheesh Bhandari Erjie Xia Lingguo Kong Xiaohua Zhang Ouchen Wang 
Acta Biochim Biophys Sin 2020,52(2):116–124 https://doi.org/10.1093/abbs/gmz144 In the original version of this manuscript,an error was found in Figure 4.The correct figure is as follows.The authors apologize for the...
关键词：INVASION COR FIGURE 
Corrigendum to:HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells
《Acta Biochimica et Biophysica Sinica》2025年第2期326-326,共1页Xinxin Kou Xiaoxia Yang Zheng Zhao Lei Li 
Acta Biochim Biophys Sin 2024,56(3):356–365 https://doi.org/10.3724/abbs.2023246 In the originally published version of this article,the Author′s affiliation was set incorrectly.This has now been corrected,and the a...
关键词：Cancer COR CISPLATIN 
Battling pain from osteoarthritis:causing novel cell death
《Acta Biochimica et Biophysica Sinica》2025年第2期169-181,共13页Yuheng Zhang Huaqiang Tao Liyuan Zhang Xueyan Li Yi Shi Wen Sun Wenlong Chen Yuhu Zhao Liangliang Wang Xing Yang Chengyong Gu 
supported by the grants from the Program of Jiangsu Science and Technology Department(Nos.BK20211083 and BE2022737);the Program of Suzhou Health Commission(Nos.GSWS2020078,SZXK202111,and GSWS2022002);the Program of Suzhou Science and Technology Department(No.SKY202306).
Osteoarthritis(OA)is a significant contributor to pain and disability worldwide.Pain is the main complaint of OA patients attending the clinic and has a large impact on their quality of life and economic standards.How...
关键词：OSTEOARTHRITIS PAIN cell death PYROPTOSIS ferroptosis NECROPTOSIS 
Targeting LINC070974 inhibits lung adenocarcinoma cell proliferation and progression by interacting with Y-box binding protein 1
《Acta Biochimica et Biophysica Sinica》2025年第2期182-194,共13页Lin Liu Pengfei Gong Xueling Li Li Zhang Jiale Niu Jinhui Zhu Ziwei Wang Xingwang Long Tenghui Cao Yewen Liu Ganglin Wang Tingming Fu Liang Sun Wei Li 
supported by the grants from the National Natural Science Foundation of China(Nos.81970753 and 31970636);the China Postdoctoral Science Foundation(No.2022M721989);the Wenzhou Science and Technology Bureau Foundation(No.ZY2021011).
Non-small cell lung cancer(NSCLC)is the leading cause of cancer-related mortality worldwide.Increasing evidence suggests that long noncoding RNAs play crucial roles in lung cancer pathogenesis.We previously identified...
关键词：LINC070974 non-small cell lung cancer Y-box binding protein 1 cyclinD1 nebulized inhalation 
TCF3 as a multidimensional biomarker:oncogenicity,genomic alterations,and immune landscape in pan-cancer analysis
《Acta Biochimica et Biophysica Sinica》2025年第2期195-208,共14页Huiling Nie Yang Yu Siqi Zhou Yue Xu Xi Chen Xun Qin Zhangyu Liu Jiayu Huang Hailiang Zhang Jin Yao Qin Jiang Bingbing Wei Xiaojian Qin 
supported by the grants from the National Natural Science Foundation of China(Nos.82171074,81970809 and 81570859);the Suzhou Medical Innovation Application Research Project(No.SZM2023027).
Transcription factor 3(TCF3),a pivotal member of the TCF/LEF family,plays a critical role in tumorigenesis.Nonetheless,its impact on the tumor microenvironment(TME)and cancer phenotypes remains elusive.We perform an e...
关键词：TCF/LEF family TCF3 pan-cancer analysis prognosis tumor microenvironment(TME) epithelial-mesenchymal transition(EMT) 
Using protein turnover assay to explore the drug mechanism of Carfilzomib
《Acta Biochimica et Biophysica Sinica》2025年第2期209-222,共14页Yonghui Tao Xinyu Ding Caiwei Jia Chengcheng Wang Chuanyin Li 
supported by the grants from the Shanghai Sailing Program(19YF1444700);the National Natural Science Foundation of China(Nos.31900804 and 82304563);the Guizhou Province Science and Technology Foundation([2020]1Y086);the Science and Technology Foundation of Guizhou Provincial Health Commission(No.gzwkj2022-219).
Carfilzomib(CFZ)is the second-generation proteasome inhibitor that is approved by Food and Drug Administration(FDA)of USA for the treatment of relapsed and refractory multiple myeloma.Although the preclinical and clin...
关键词：Carfilzomib multiple myeloma PROFILING protein homeostasis 
CircMALAT1 promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma via the miR-512-5p/VCAM1 axis
《Acta Biochimica et Biophysica Sinica》2025年第2期223-236,共14页Meixia Zhang Mingyan He Liangliang Bai Fan Du Yingping Xie Bimin Li Yuming Zhang 
supported by grants from the National Natural Science Foundation of China(Nos.82003121 and 82260514);Training program for academic and technical leaders in major disciplines-Young Talents(No.20232BCJ23039);the Application of screening and endoscopy for esophageal and gastric varices in liver cirrhosis in Jiangxi Province(No.20202BBGL73093).
Circular RNAs play a pivotal role in the progression of various cancers.In our previous study,we observed high expression of the circRNA MALAT1(cMALAT1)in intrahepatic cholangiocarcinoma(ICC)cells co-incubated with ac...
关键词：circular MALAT1 ICC miR-512-5p VCAM1 EMT 
Alpha-lipoic acid targets KLF7 expression to inhibit cervical cancer progression
《Acta Biochimica et Biophysica Sinica》2025年第2期237-249,共13页Yi Mao Hongtao Li Gang Xu Jiazhen Tian Yuechan Chen Zhiwei Zhang 
supported by the grants from the National Natural Science Foundation of China(Nos.32360825,31960647 and 31501947);the Youth Innovative Talents Project of Shihezi University(Nos.ZZZC202183 and CXBJ201905).
It is unclear what part KLF7 plays in cervical cancer.In this study,immunohistochemical and bioinformatics analyses reveal that KLF7 expression is lower in normal cervical tissues than in cervical cancer tissues,and t...
关键词：cervical cancer Krüppel-like factor 7 alpha-lipoic acid reprogramming of energy metabolism 
Diacylglycerol kinaseγfacilitates the proliferation and migration of neural stem cells in the developing neural tube
《Acta Biochimica et Biophysica Sinica》2025年第2期250-260,共11页Huilin Cui Jiazheng Du Jianshan Xie Jixia Zhang Yun Tao Yige Huang Lei Li Ximei Cao Yu Zhang 
supported by the grant from the National Science Foundation of Shanxi Province(No.20210302123321).
In this study,we aim to investigate diacylglycerol kinase(DGK)γexpression in developing neural tubes(NTs)and its effects on neural stem cell(NSC)proliferation and migration.Whole-mount in situ hybridization(WMISH)and...
关键词：diacylglycerol kinaseγ protein kinase C neural tube neural stem cell cell proliferation cell migration 
Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects
《Acta Biochimica et Biophysica Sinica》2025年第2期261-273,共13页Yunguang Wang Xinxin He Hua Zhang Wei Hu 
supported by the grants from the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Hangzhou Health Science and Technology Plan-Major Project(No.Z20220026).
Intestinal ischemia-reperfusion(I/R)injury severely affects the lungs.Germacrone(Ger)possesses anti-inflammatory and antioxidant properties.However,it is unclear whether it protects the lungs from I/R injury.In this s...
关键词：lung injury GERMACRONE macrophage polarization mitochondrial function intestinal ischemia-reperfusion 
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