云南高校图书馆联盟文献共享服务平台- STIMULATOR

STIMULATOR: 作品数：96被引量：165H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王蕊于洋陈付强欧瑜吕正兵更多>>; 相关机构：青岛市市立医院中国药科大学温州医学院天津医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金上海市青年科技启明星计划更多>>

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration: 《Neural Regeneration Research》2025年第7期2005-2007,共3页Bryan Sun Lulin Li Jian Luo; partially supported by a grant(RF1AG059694)from the U.S.National Institutes of Health;by Polytrauma System of Care,VAPAHCS(to JL)。; The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of neuroinflammation.While current studies primarily attribute its effects to neurons and glial ce...; 关键词：STIMULATOR INTERFERON inflammation

Death domain-associated protein(Daxx)impairs colon cancer chemotherapy by inhibiting the cGAS-STING pathway: 《Oncology Research》2025年第5期1149-1159,共11页XI ZHU KAI HUANG XIAOMING KAO ZHAOHUI TANG WENJIE GUO TIANCONG WU QIURONG LI; supported by the National Natural Science Foundation of China(82202956)。; Background:Colorectal cancer(CRC)holds the third position in global cancer prevalence mortality.Although chemotherapy is a conventional treatment,recent investigations have shed light on the therapeutic potential of t...; 关键词：Death domain-associated protein(Daxx) Stimulator of the interferon gene(STING) Colorectal cancer(CRC) CHEMOTHERAPY

Bidirectional regulation of the cyclic guanosine monophosphateadenosine monophosphate synthase-stimulator of interferon gene pathway and its impact on hepatocellular carcinoma: 《World Journal of Gastrointestinal Oncology》2025年第2期246-261,共16页Ai-Yu Nie Zhong-Hui Xiao Jia-Li Deng Na Li Li-Yuan Hao Sheng-Hao Li Xiao-Yu Hu; Supported by the National Natural Science Foundation of China,No.81973840;the Sichuan Provincial Administration of Traditional Chinese Medicine Major Science and Technology projects,No.2021XYCZ004。; BACKGROUND Hepatocellular carcinoma(HCC)ranks as the fourth leading cause of cancerrelated deaths in China,and the treatment options are limited.The cyclic guanosine monophosphate-adenosine monophosphate synthase(cGAS...; 关键词：Hepatocellular carcinoma Cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon gene Interferon genes The metastasis of a tumor IMMUNOLOGY

Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling: 《Genes & Diseases》2024年第6期381-394,共14页Guoxiang Zhou Xiaowen Wang Mingyu Guo Can Qu Lei Gao Jiang Yu Yuanjing Li Suxin Luo Qiong Shi Yongzheng Guo; supported by grants from the Natural Science Foundation of China (No.82070238);the China Postdoctoral Science Foundation (No.2022M720601);the Natural Science Foundation of Chongqing,China (No.CSTB2022NSCQMSx0913);the Program for Youth Innovation in Future Medicine,Chongqing Medical University (No.W0168);the Science Fund of the First Affiliated Hospital of Chongqing Medical University (No.PYJJ2021-05);the Postdoctoral Incubation Project of The First Affiliated Hospital of Chongqing Medical University (No.CYYY-BSHPYXM-202204)。; Stimulator of interferon genes(STING)has recentlybeen found to play a crucial role in cardiac sterile inflammation and dysfunction.The role of stimulator of interferon genes(STING)in cardiac sterile inflammation and d...; 关键词：Cardiac remodeling Mitochondrial autophagy mtDNA Sterile inflammation STING

cGAS-STING signaling pathway in lung cancer:Regulation on antitumor immunity and application in immunotherapy: 《Chinese Medical Journal Pulmonary and Critical Care Medicine》2024年第4期257-264,共8页Jing Wu Yingyao Chen Mengqing Xie Xin Yu Chunxia Su; supported by the National Natural Science Foundation of China(Nos.82373320,82072568);the Shanghai Shenkang Hospital Development Center(No.SHDC12020110);the Shanghai Pulmonary Hospital Fund(No.fkzr2403);the National Key Research and Development Program of China(No.2023YFC2508603)。; The innate immune system has a primary role in defending against external threats,encompassing viruses,bac-teria,and fungi,thereby playing a pivotal role in establishing robust protection.Recent investigations have sh...; 关键词：Cyclic GMP-AMP synthase-stimulator of interferon genes(cGAS-STING) Lung cancer Tumor microenvironment

Role of cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes pathway in diabetes and its complications: 《World Journal of Diabetes》2024年第10期2041-2057,共17页Ming-Wei Fan Jin-Lan Tian Tan Chen Can Zhang Xin-Ru Liu Zi-Jian Zhao Shu-Hui Zhang Yan Chen; Supported by the Natural Science Foundation of Shandong Province,No.ZR2022MH153;“Clinical+X”Project Fund of Binzhou Medical College,No.BY2021LCX11.; Diabetes mellitus(DM)is one of the major causes of mortality worldwide,with inflammation being an important factor in its onset and development.This review summarizes the specific mechanisms of the cyclic guanosine mo...; 关键词：Cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes Diabetes mellitus Inflammation Glycolipid metabolism Diabetes gastroenteropathy Nonalcoholic fatty liver disease Diabetes cardiovascular disease Diabetes nephropathy

Prognostic significance and underlying mechanisms of STING in lung adenocarcinoma: 《Chinese Medical Journal》2024年第20期2501-2503,共3页Haohua Zhu Yufeng Cao Jingyu Lu Lei Guo Rongrong Luo Huiyang Shi Yu Feng Yutao Liu Puyuan Xing Hongyu Wang Yuankai Shi Jie Ma Xingsheng Hu; founded by Beijing Xisike Clinical Oncology Research Foundation(No.Y-2019AZMS-0439).; To the Editor:Genomic instability is a hallmark of cancer,with increasing genetic changes and DNA damage.The accumulated mutations in the tumor genome can generate neoantigens,which can trigger an antitumor immune res...; 关键词：INTERFERON STIMULATOR ADENOCARCINOMA

Add-on perceptual learning on refractive amblyopia in children: 《International Journal of Ophthalmology(English edition)》2024年第10期1850-1856,共7页Heng-Chiao Huang Wan-Hua Cho Po-Chiung Fang Pei-Wen Lin Yi-Hao Chen Hsiu-Mei Huang; Supported by the Kaohsiung Chang Gung Memorial Hospital and University College of Medicine(No.CMRPG8L1231,No.CMRPG8L1232,Kaohsiung,Taiwan).; AIM:To evaluate the visual outcomes of standard amblyopic treatment add-on training via perceptual learning in refractive amblyopic children and to identify the risk factors for treatment failure.METHODS:Retrospective...; 关键词：AMBLYOPIA amblyopic children add-on Cambridge Visual Stimulator training ASTIGMATISM

Advances in the prerequisite and consequence of STING downstream signalosomes: 《Medical Review》2024年第5期435-451,共17页Xinliang Lu Xiaobing Li Lili Li Chuanhui Han Sirui Li; National Natural Science Foundation of China (82000003);China Postdoctoral Science Foundation (2023M743039);National Key Research and Development Program of China (2022YFC3401400).; The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)pathway is an evolving DNA-sensing mechanism involved in innate immunity and pathogen defense that has been optimized while remaining conserved.As...; 关键词：stimulator of interferon genes signalosomes cellular heterogeneity cancer therapeutics

Advanced nerve regeneration enabled by neural conformal electronic stimulators enhancing mitochondrial transport: 《Bioactive Materials》2024年第9期287-301,共15页Hao Bai Siqi Zhang Huiran Yang Jing Wang Hongli Chen Jia Li Lin Li Qian Yang Bo Peng Ziyi Zhu Siyuan Ni Keyin Liu Wei Lei Tiger H.Tao Yafei Feng; supported by the National Natural Science Foundation of China(82172476,82172393).; Addressing peripheral nerve defects remains a significant challenge in regenerative neurobiology.Autograftsemerged as the gold-standard management,however,are hindered by limited availability and potential neuromaform...; 关键词：Silk materials Electronic stimulator Structural reconfiguration Peripheral nerve regeneration Mitochondrial transport

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