supported by the Medical Research Council(MRC)(grant number G0700763);by the University of Nottingham,Nottingham,UK.
The intestinal epithelium undergoes rapid renewal,with the entire epithelial layer replaced within five days.Intestinal stem cells(ISCs),located in the intestinal crypts,generate all differentiated cell types necessar...
National Natural Science Foundation of China(32071277);Science and Technology Program of Hebei Province(216Z2602G);Natural Science Foundation of Hebei Province(C2021201012);Interdisciplinary Research Program of Natural Science of Hebei University(DXK202006).
Spindlin1(SPIN1)is a unique multivalent histone modification reader that plays a role in ribosomal RNA transcription,chromosome segregation,and tumorigenesis.However,the function of the extended N-terminal region of S...
MICINN grant number PID2019-106220RB100.Instituto de Salud CarlosⅢ,Spain,grant PI200335,(all co-financed through Fondo Europeo de Desarrollo Regional(FEDER)"Una manera de hacer Europa");supported by a grant FPU15/04669,funded by Ministerio de Educacion,Cultura y Deporte,Spain.JMH FPI-UAM 2021 from Universidad Auton-oma de Madrid(Molecular BioSciences PhD programme).
Gastric cancer(GC)is worldwide the sixth most diagnosed and third leading cause of cancer deaths,with poor and late prognosis,probably due to post-surgery adjuvant treatment resistance and lack of a thorough panel of ...
Supported by National Natural Science Foundation-funded Project:the Biological Mechanism of Lingguizhugan Decoction Treating Alzheimer’s Disease via Regulating Brain Lymphatic Drainage System(No.82074504);the Priority Academic Program Development of Jiangsu Higher Education Institutions(Integration of Chinese and Western Medicine);Natural Science Foundation of the Jiangsu Higher Education Institutions-funded Project:to Explore the Mechanism of Sanwubai San Regulating Gut Microbiota Against Colorectal Cancer By IL-23/ΓδT17/IL-17 Axis(19KJB360003)。
OBJECTIVE:To uncover the anti-tumor effects and potential mechanism of Sanwu Baisan Decoction(三物白散,SWB)in treatment of colorectal cancer(CRC)in mice.METHODS:Therapeutic effect was evaluated based on body weight ga...
supported by the National Natural Science Foundation of China(No.81974424,81874133,81772903 and 81903032);Natural Science Foundation of Hunan Province,China(No.2018JJ2630 and 2021JJ41013);the Huxiang Young Talent Project,China(No.2018RS3024);the China Postdoctoral Science Foundation(No.2020M672520);the Youth Fund of Xiangya Hospital,China(No.2018Q011).
Long non-coding RNAs(lncRNAs)are a novel class of non-coding RNA(ncRNA),that have been studied extensively in the field of tumor research in recent years.In the case of tumor-associated lncRNAs,lncRNA cytoskeleton reg...
National Natural Science Foundation of China,Grant/Award Number:81901006;Guangdong Basic and Applied Basic Research Foundation,Grant/Award Number:2020A1515110051;Scientific Research Talent Cultivation Project of Stomatological Hospital,Southern Medical University,Grant/Award Number:RC202005;Science Research Cultivation Program of Stomatological Hospital,Southern Medical University,Grant/Award Number:PY2020002。
Background:Head and neck squamous cell carcinoma(HNSCC)is one of the most frequent malignancies worldwide and is characterized by unfavorable prognosis,high lymph node metastasis and early recurrence.However,the molec...