DIETHYLNITROSAMINE

作品数：30被引量：96H指数：6
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相关领域：医药卫生更多>>
相关作者：王晓明朱海英王新民谢东甫胡以平更多>>
相关机构：第二军医大学福州总医院首都医科大学更多>>
相关期刊：《胃肠病学》《癌变．畸变．突变》《Chinese Medical Sciences Journal》《Chinese Journal of Cancer Research》更多>>
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Corrigendum to“Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis”[Liver Res.2(2018)100e107]
《Liver Research》2023年第2期164-164,共1页Jonathan Choiniere Matthew Junda Lin Li Wang Jianguo Wu 
The authors regret
关键词：removed LIVER THANK 
Anti-Fibrotic Effects of Calotropis procera (Ait.) R.Br Roots Barks against Diethylnitrosamine-Induced Hepatic Fibrosis in Rats
《Journal of Biosciences and Medicines》2023年第4期332-349,共18页Ernest Nogma Sombié Tata Kadiatou Traoré Abdoul-Nassiré Derra Jotham Yhi-Pênê N’do Wendkouni L. M. E. Belem-Kabré Noufou Ouédraogo Adama Hilou André Tibiri 
Background: Liver diseases including chronic hepatitis, steatosis, fibrosis, cirrhosis and liver cancer are now a public health problem. In 2002, cirrhosis accounted for 27.63% of hepatobiliary diseases in Burkina Fas...
关键词：Hepatic Fibrosis Calotropis procera Anti-Fibrotic Properties Burkina Faso 
Rhizoma paridis saponins protected against liver injury in diethylnitrosamine-induced mice
《Traditional Medicine Research》2023年第2期7-12,共6页Chen Luo Jing-Wen Yao Shu-Li Man Wen-Yuan Gao 
Background:Diethylnitrosamine,one of food additives,possessed a strong carcinogenic effect in human.Rhizoma paridis saponins,as the main active components of Paris polyphylla,have a good anti-cancer effect in our prev...
关键词：Rhizoma paridis saponins liver injury DIETHYLNITROSAMINE METABOLITES 
Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BioID assay
《Acta Biochimica et Biophysica Sinica》2021年第9期1237-1246,共10页Fei Chen Hongyu Yan Chu Guo Huiqin Zhu Jing Yi Xuxu Sun Jie Yang 
the grants from the National Natural Science Foundation of China(No.31771522);Shanghai Municipal Science and Technology Commission(No.16ZR1418400);the Innovative Research Team of High-level Local Universities in Shanghai,the National Natural Science Foundation of China(No.31970587 to Dr Xuxu Sun);the Foundation of Shanghai Oriental Scholar(No.TP2018045).
SUMOylation of proteins regulates cell behaviors and is reversibly removed by small ubiquitin-like modifier(SUMO)-specific proteases(SENPs).The SENP family member SENP3 is involved in SUMO2/3 deconjugation and has bee...
关键词：SUMO specific peptidase 3 SUMOYLATION BioID HEPATOCYTES DIETHYLNITROSAMINE 
Multi-stress accelerated liver cancer progression in rats treated with diethylnitrosamine被引量：1
《Chinese Medical Journal》2021年第14期1762-1764,共3页Yan-Jiao Wang Hai-Yan Xu Xin-Hui Huo Si-En Fan Xin-Hua Nabi 
the National Natural Science Foundation of China(No.81560805);the Xinjiang Tianshan Talent Project.
To the Editor:Eighty-four 6-week-old male Wistar rats,weighing from 120 to 180 g,were categorized into three groups:normal control(NC)group,diethylnitrosamin(DEN)group,and multi-stress group.In the NC group,rats were ...
关键词：RATS maintained STRESS 
Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats:Molecular study
《World Journal of Hepatology》2021年第3期328-342,共15页Amany Helmy Hasanin Eman K Habib Nesreen El Gayar Marwa Matboli 
BACKGROUND Diethylnitrosamine(DEN)induces hepatic neoplastic lesions over a prolonged period.AIM To investigate the promotive action of 2-acetylaminofluorene(2-AAF)when combined with DEN in order to develop a rat mode...
关键词：Acetylaminofluorene Hepatic precancerous lesion DIETHYLNITROSAMINE AUTOPHAGY APOPTOSIS MicroRNA 
BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis
《World Journal of Hepatology》2021年第3期343-361,共19页Chrystelle L Vilfranc Li-Xiao Che Krushna C Patra Liang Niu Olugbenga Olowokure Jiang Wang Shimul A Shah Chun-Ying Du 
Supported by NIH(Du CY),No.R21CA241025-01;NIH(Du CY),No.RO1CA158323;NCI RO1 Diversity Supplement(Du CY),No.R01CA158323-05S;National Center for Advancing Translational Sciences of the National Institutes of Health(Du CY),No.2UL1TR001425-05A1;University of Cincinnati Center for Environmental Genetics-NIH/NIEHS Award(Du CY),No.P30 ES006096;Pathways to Cancer Therapeutics T32(Du CY and Vilfranc CL),No.CA117846-12.
BACKGROUND BIR repeat-containing ubiquitin conjugating enzyme(BRUCE)is a liver tumor suppressor,which is downregulated in a large number of patients with liver diseases.BRUCE facilitates DNA damage repair to protect t...
关键词：BIR repeat-containing ubiquitin conjugating enzyme DIETHYLNITROSAMINE Mouse model Liver fibrosis Liver cancer Hepatocellular carcinoma 
Annona muricata fruit extract protects against diethylnitrosamine-induced hepatocellular cancer in rats被引量：1
《Asian Pacific Journal of Tropical Medicine》2019年第6期272-282,共11页Subin Varghese Thomas John Paul Akhila Hosur Shrungeswara Subhankar Biswas Aarti Abhishek Shah Chandrashekar Kodangala Subraya Yogendra Nayak 
Objective: To evaluate the anticancer potentials of Annona muricata fruit by in vitro and in vivo methods. Methods: The ethanolic extract of Annona muricata fruit was prepared by Soxhlet extraction method and further ...
关键词：HepG2-cells Apoptosis LIVER CANCER ACETOGENINS Rat LIVER CANCER Scratch wound assay 
Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis被引量：1
《Liver Research》2018年第2期100-107,共8页Jonathan Choiniere Matthew Junda Lin Li Wang Jianguo Wu 
This work is supported by the US National Institutes of Health(NIH)R01ES025909,R01DK104656,R01DK080440,R21AA022482,R21AA024935;VA Merit Award 1I01BX002634,P30 DK34989(Yale Liver Center);the National Natural Scientific Foundation of China(Grant No.81572443)(to L.Wang).
Background and Aim:Pyruvate dehydrogenase kinase 4(PDK4)is a metabolism switch that regulates glucose oxidation and the tricarboxylic acid cycle(TCA cycle)in the mitochondria.Liver detoxifies xenobiotics and is const...
关键词：HEPATOCYTES Cell death Liver injury Pyruvate dehydrogenase kinase 4(PDK4) 
Ethanol Extract of Phellinus merrillii Protects against Diethylnitrosamine- and 2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Rats被引量：1
《Chinese Journal of Integrative Medicine》2017年第2期117-124,共8页YANG Chun-hung CHANG Heng-yuan CHEN Yi-chuan LU Chia-chen HUANG Shyh-shyun HUANG Guan-jhong LAI Hsin-chih 
Supported by China Medical University Tsuzuki Institute for Traditional Medicine(No.CMU95-PH-11 and No.CMU97-232);the National Science Council(No.NSC 95-2320-B-182-059-MY3);Chang Gung University(No.CMRPD160271),Taiwan,China
Objective： To study whether the ethanol extract of Phellinus merrillii（EPM） has chemopreventive potential against liver carcinogenesis. Methods： Thirty male Spraque-Dawley rats were randomly divided into control g...
关键词：hepatocarcinogenesis Phellinus merrillii diethylnitrosamine 2-acetylaminofluorene chemoprevention 
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