NANOSUSPENSIONS

作品数：15被引量：41H指数：5
导出分析报告
相关领域：医药卫生更多>>
相关作者：张辉更多>>
相关机构：中国药科大学更多>>
相关期刊：《Journal of Bionic Engineering》《Chinese Journal of Natural Medicines》《Advanced Fiber Materials》《中国药理通讯》更多>>
相关基金：国家自然科学基金上海市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Insight into the in vivo fate of intravenous herpetrione amorphous nanosuspensions by aggregation-caused quenching probes被引量：4
《Chinese Chemical Letters》2022年第11期4948-4951,共4页Lingyu Hang Chengying Shen Baode Shen Hailong Yuan 
supported by the National Natural Science Foundation of China(Nos.81873092,81573697,82174074,81803741)。
Intravenous nanosuspensions are attracted growing attention as a viable strategy for development of intravenous formulations of poorly water-soluble drugs.However,only few information about the biological fate of intr...
关键词：Amorphous nanosuspensions Herpetrione In vivo fate Intravenous delivery Aggregation-caused quenching 
Carrier-free highly drug-loaded biomimetic nanosuspensions encapsulated by cancer cell membrane based on homology and active targeting for the treatment of glioma被引量：7
《Bioactive Materials》2021年第12期4402-4414,共13页Yueyue Fan Yuexin Cui Wenyan Hao Mengyu Chen Qianqian Liu Yuli Wang Meiyan Yang Zhiping Li Wei Gong Shiyong Song Yang Yang Chunsheng Gao 
We are grateful for the financial support from National Natural Science Foundation of China(Grant No.82073783).
Nanosuspensions,as a new drug delivery system for insoluble drugs,are only composed of a drug and a small amount of stabilizer,which is dispersed in an aqueous solution with high drug-loading,small particle size,high ...
关键词：NANOSUSPENSIONS Cancer cell membrane Biomimetic drug-delivery systems GLIOMAS Blood-brain barrier Paclitaxel 
Combined nanosuspensions from two natural active ingredients for cancer therapy with reduced side effects被引量：1
《Chinese Chemical Letters》2021年第9期2877-2881,共5页Yonghui Qiao Zhihao Wei Tingting Qin Rufeng Song Zhiqiang Yu Qi Yuan Juan Du Qingbing Zeng Lanlan Zong Shaofeng Duan Xiaohui Pu 
supported by Leading Talents Program of Zhongyuan Science and Technology Innovation(No.204200510022);Program for Innovative Research Team(in Science and Technology)in University of Henan Province(No.21IRTSTHN026);Henan Provincial Key Research-Development and Special Project For Promotion(Nos.192102310030,202102310483);Kaifeng Science and Technology Development Plan Project and the Key Project of Science(Nos.1903034,1908006);the Key Project of Science and Technology Research funded by the Henan Provincial Department of Education(No.19A350001)。
Tumor drug resistance and systemic side effects of chemotherapeutic drugs are the main reasons for the failure of cancer treatment.In recent years,it was found that some natural active ingredients can reverse MDR and ...
关键词：Combination therapy Multidrug resistance NANOSUSPENSIONS Antitumor activity IMMUNOMODULATORY 
Facile pathway to generate agrochemical nanosuspensions integrating super-high load, eco-friendly excipients, intensified preparation process, and enhanced potency被引量：1
《Nano Research》2021年第7期2179-2187,共9页Zhengxi Zhu Chuanhua Shao Yanlin Guo Jianguo Feng Chong Chen and Haibin Yang 
The work was financially supported by the National Natural Science Foundation of China(No.21544005);the Basic Research Program(Natural Science Foundation for Young Scholars)of Jiangsu Province(No.BK20170489);the Materials and Chemical Engineering Research Center of Xinjiang Production and Construction Corps(No.2018BTRC003);the Joint Project of Yangzhou City and Higher Education Institutions(No.YZ2019127);the Innovation Incubation Project of Yangzhou University(No.2019CXJ025);the Priority Academic Program Development of Jiangsu Higher Education Institutions.
An aqueous nanosuspension of agrochemicals unlike pharmaceutics has to achieve massive production in an effective way,capable to ensure sufficient profits in commercialization.This work implements the flash nanoprecip...
关键词：turbulent confined jet mixing flash nanoprecipitation agrochemical nanosuspensions super-high loads high biological efficacy eco-friendly formulations 
Geometrical Deposits on Microstructured Surfaces被引量：1
《Journal of Bionic Engineering》2020年第4期851-865,共15页Veronika Kubyshkina Daniel Orejon Coinneach Mackenzie Dover Khellil Sefiane 
Author Veronika Kubyshkina thanks EPSRC for supporting this research through a DPT scholarship(EP/N011341/1);The authors would like to acknowledge the support of the European space Agency(ESA),through grant Convection and Interfacial Mass Exchange(EVAPORATION)ESA Contract Number 4000129506/20/NL/PG.
Research into evaporating droplets on patterned surfaces has grown exponentially,since the capacity to control droplet morphology has proven to have significant technological utility in emerging areas of fundamental r...
关键词：geometrical wetting tuneable surface topography NANOSUSPENSIONS deposition patterns particle assembly 
Preparation and Characterization of Paclitaxel/Chitosan Nanosuspensions for Drug Delivery System and Cytotoxicity Evaluation In Vitro被引量：3
《Advanced Fiber Materials》2019年第2期152-162,共11页Yongjia Liu Fengren Wu Yongle Ding Bangshang Zhu Yue Su Xinyuan Zhu 
National Natural Science Foundation of China(Grant No:51373099);State Key Laboratory of open funds of China from Donghua University(LK1411).
In this study,we prepared paclitaxel/chitosan(PTX/CS)nanosuspensions(NSs)with different mass ratios of PTX and CS(1.5:2,2:2,and 2.5:2),for controlled drug delivery purposes.For attachment and dispersion in water mediu...
关键词：PACLITAXEL CHITOSAN NANOSUSPENSIONS Drug release Cytotoxicity in vitro 
Permeation into but not across the cornea:Bioimaging of intact nanoemulsions and nanosuspensions using aggregation-caused quenching probes被引量：5
《Chinese Chemical Letters》2018年第12期1834-1838,共5页Dailei Liu Bo Wan Jianping Qi Xiaochun Dong Weili Zhao Wei Wu Yikang Dai Yi Lu Zhongjian Chen 
supported by the National Natural Science Foundation of China(Nos.81872815,81573363,81690263,21372063);the Natural Science Foundation of Shanghai(No.16ZR1403500)
Nanoemulsions(NEs) and nanosuspensions(NSs) show great potential in enhancing the ocular bioavailability of therapeutics through topical delivery. However, transocular fate of intact NEs and NSs is still inconclusive....
关键词：Transocular transportation Topical administration Aggregation-caused quenching probe NANOEMULSIONS NANOSUSPENSIONS 
Parenteral nanosuspensions:a brief review from solubility enhancement to more novel and specific applications被引量：8
《Acta Pharmaceutica Sinica B》2018年第5期733-755,共23页Eknath Ahire Shreya Thakkar Mahesh Darshanwad Manju Misra 
Department of Science and Technology,India for providing funding to conduct research work (DST INSPIRE LSBM-13 and SERB EMR/2016/007966)
Advancements in in silico techniques of lead molecule selection have resulted in the failure of around 70% of new chemical entities(NCEs). Some of these molecules are getting rejected at final developmental stage resu...
关键词：PARENTERAL NANOSUSPENSION STABILIZER In vivo FATE Solidification SCALABILITY 
Improved stability and oral bioavailability of Ganneng dropping pills following transforming lignans of herpeto- spermum caudigerum into nanosuspensions被引量：6
《Chinese Journal of Natural Medicines》2018年第1期70-80,共11页LI Juan-Juan CHENG Ling SHEN Gang QIU Ling SHEN Cheng-Ying ZHENG Juan XU Rong YUAN Hai-Long 
financially supported by the National Key New Drugs Innovation Foundation(No.2016X09101073);the National Natural Science Foundation of China(No.81573697)
The present study was designed to improve storage stability and oral bioavailability of Ganneng dropping pills(GNDP) by transforming lignans of Herpetospermum caudigerum(HL) composed of herpetrione(HPE) and herpetin(H...
关键词：Ganneng dropping pills Lignans Herpetospermum caudigerum NANOSUSPENSIONS STABILITY Oral bioavailability 
Protective effects of resveratrol nanosuspensions loaded in situ hydrogel on Alzheimer disease model mice after intranasal administration
《中国药理学与毒理学杂志》2017年第5期468-469,共2页WANG Hong-shen XU Yan-hao CHANG Sheng LI Li WANG Hao HAO Ji-fu 
The project supported by the National Training Program of Innovation and Entrepreneurship for Undergraduates(201610439108)
OBJECTIVE To evaluate the protective effects of resveratrol nanosuspensions loaded in situ hydrogel on Alzheimer disease model mice after intranasal administration. METHODS Resveratrol nanosuspensions were fabricated ...
关键词：RESVERATROL intranasal administration Alzheimer disease water maze experiments 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部