NANOSUSPENSION

作品数：9被引量：21H指数：3
导出分析报告
相关领域：医药卫生更多>>
相关作者：刘瑜洁齐宪荣潘卫三更多>>
相关机构：北京大学沈阳药科大学更多>>
相关期刊：《Journal of Chinese Pharmaceutical Sciences》《Asian Pacific Journal of Tropical Biomedicine》《Advances in Nanoparticles》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-9
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Enhancing pharmaceutical potential and oral bioavailability of Allium cepa nanosuspension in male albino rats using response surface methodology
《Asian Pacific Journal of Tropical Biomedicine》2022年第1期26-38,共13页Fatiqa Zafar Nazish Jahan Shaukat Ali Saba Jamil Riaz Hussain Saba Aslam 
support was received from Higher Education Commission of Pakistan under grant agreement number[20-2(3)/NIBGE,Fbd/ASIP/R&D/HEC/2016/697].
Objective:To enhance the pharmaceutical potential and oral bioavailability of quercetin contents of Allium cepa peel extract by novel nanosuspension technology.Methods:Nanoprecipitation approach was successfully used ...
关键词：Allium cepa NANOPRECIPITATION Pharmaceutical potential Particle size Polydispersity index Stability TOXICITY QUERCETIN 
Nanosuspension enhances dissolution rate and oral bioavailability of Terminalia arjuna bark extract in vivo and in vitro被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2020年第4期164-171,共8页Fatiqa Zafar Nazish Jahan Khalil-Ur-Rahman Muhammad Rafique Asi Waseeq-Ul-Islam Zafar 
Objective:To enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract by formulating its nanosuspension.Methods:Nanoprecipitation approach was used for the formulation of nanosuspension ...
关键词：TERMINALIA arjuna NANOSUSPENSION BIOAVAILABILITY Stability Toxicity Polysorbate-80 
Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method被引量：5
《Asian Journal of Pharmaceutical Sciences》2019年第6期649-657,共9页Fang Li Linsen Li Shaoning Wang Yan Yang Jia Li Dongchun Liu Sijie Zhang Siling Wang Hui Xu 
financial support from the National Basic Research Program of China(973 Program,No.2009CB930300)
The objective of this work is to construct a nanosuspension drug delivery system of probucol,a BCS II drug,in order to improve its dissolution and oral bioavailability.The wet milling procedure using planetary beads-m...
关键词：PROBUCOL NANOSUSPENSION Ternary STABILIZERS systems PLANETARY beads-milling Bioavailability 
Cytotoxic Effect of Propolis Nanoparticles on Ehrlich Ascites Carcinoma Bearing Mice
《Advances in Nanoparticles》2019年第4期55-70,共16页Jawharah A. Abdo Fahd M. Alsharif Nivin Salah Om Ali Y. Elkhawaga 
Background and objective Previous studies have demonstrated the anti-cancer effects of propolis. However, its use is limited because of its poor bioavailability. In the present study, the major objective was to improv...
关键词：PROPOLIS NANOSUSPENSION Ehrlich ASCITES Carcinoma Cells CYTOTOXICITY Immune-Stimulation Cell Cycle 
Parenteral nanosuspensions:a brief review from solubility enhancement to more novel and specific applications被引量：8
《Acta Pharmaceutica Sinica B》2018年第5期733-755,共23页Eknath Ahire Shreya Thakkar Mahesh Darshanwad Manju Misra 
Department of Science and Technology,India for providing funding to conduct research work (DST INSPIRE LSBM-13 and SERB EMR/2016/007966)
Advancements in in silico techniques of lead molecule selection have resulted in the failure of around 70% of new chemical entities(NCEs). Some of these molecules are getting rejected at final developmental stage resu...
关键词：PARENTERAL NANOSUSPENSION STABILIZER In vivo FATE Solidification SCALABILITY 
Preparation,characterization and pharmacokinetics of 10-hydroxycamptothecin nanosuspension被引量：1
《Journal of Chinese Pharmaceutical Sciences》2017年第8期574-581,共8页张毅 詹颖 庞宁 刘瑜洁 程士轩 李骥 杜祎甜 齐宪荣 
NSFC(Grant No.81473156,81673365);Fangzheng Foundation for funding of the work
10-Hydroxycamptothecin （HCPT） is a broad-spectrum anticancer drug, while its low solubility and instability severely limit its application. In this study, HCPT nanosuspension （HCPT-NSP）, also known as nanocrystal,...
关键词：10-HYDROXYCAMPTOTHECIN NANOSUSPENSION Nanocrystal High-pressure homogenization PHARMACOKINETICS 
Determination of dabigatran in dog plasma by LC-MS/MS and its application to a pharmacokinetic study of dabigatran etexilate nanosuspension
《Journal of Chinese Pharmaceutical Sciences》2017年第8期589-594,共6页从双晨 张媛媛 雷冏茜 宋茂远 张文茜 彭光华 殷梦雅 李佳佳 王佳星 李馨儒 
The National Basic Research Program of China(Grant No.2015CB932100)
In this study, a sensitive and rapid LC-MS/MS method was developed and validated to determine dabigatran in plasma of beagle dogs after oral administration of dabigatran etexilate nanosuspension （DABE-NS）. The analy...
关键词：DABIGATRAN Dabigatran etexilate LC-MS/MS NANOSUSPENSION PHARMACOKINETICS 
Formulation of dried lignans nanosuspension with high redispersibility to enhance stability,dissolution,and oral bioavailability被引量：6
《Chinese Journal of Natural Medicines》2016年第10期757-768,共12页SHEN Gang CHENG Ling WANG Li-Qiang ZHANG Li-Hong SHEN Bao-De LIAO Wei-Bo LI Juan-Juan ZHENG Juan XU Rong YUAN Hai-Long 
supported by the National Key New Drugs Innovation Foundation(No.2015ZX09101025);the National Science Foundation of China(No.81503169);the New Drugs Development Special Foundation of Beijing City of China(No.Z141100002214007)
Herpetospermum caudigerum lignans(HTL), one of the potential drugs with anti-hepatitis B virus and hepatoprotective effects, has limited clinical applications because of poor aqueous solubility and low bioavailability...
关键词：Herpetospermum caudigerum lignans NANOSUSPENSIONS Acid-base neutralization Saturation solubility DISSOLUTION Oral bioavailability 
Comparison of solid dispersion and nanosuspension for improvement of drug absorption被引量：1
《Asian Journal of Pharmaceutical Sciences》2016年第1期10-11,共2页Qiang Fu Mengran Guo Zhonggui He 
Currently, drug discovery technology is heavily dependent oncombinatorial chemistry and high throughput screening, resultingin more and more poorly water-soluble drugs, eitherclass II (low solubility and high permeabi...
关键词：NANOSUSPENSION SOLID DISPERSION In VITRO In VIVO 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部