HYPOXIA-REOXYGENATION

作品数:12被引量:60H指数:4
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相关领域:医药卫生更多>>
相关作者:柳兆芳杨浩汪佑霞黄家胜程光华更多>>
相关机构:皖南医学院弋矶山医院福建医科大学更多>>
相关期刊:《Science China(Life Sciences)》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金广东省自然科学基金北京市自然科学基金更多>>
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The demethylase FTO regulates the m6A modification and inflammation pathway in patients with cardiomyocytes after hypoxia-reoxygenation
《South China Journal of Cardiology》2024年第3期169-178,共10页ZHAO Hai-mei CHENG Hong JIAO Qi-hui 
supported by grants from Shenzhen Science and Technology Project(No.JCYJ20220531091817039)。
Background Myocardial ischemia-reperfusion injury is an important clinical problem.Hypoxia-reperfusion(HR)triggers a series of complex cellular reactions and pathological changes.In recent years,the role of N-6-methyl...
关键词:FTO m6A NF-k B IL-6 Anoxia and reoxygenation 
Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK/mTOR pathway in vitro被引量:9
《Journal of Integrative Medicine》2022年第4期365-375,共11页Cai-lian Fan Wan-jun Cai Meng-nan Ye Miao Chen Yi Dai 
supported by Guangdong Basic and Applied Basic Research Foundation (No. 2021A1515110055)。
Objective: Qili Qiangxin(QLQX), a compound herbal medicine formula, is used effectively to treat congestive heart failure in China. However, the molecular mechanisms of the cardioprotective effect are still unclear. T...
关键词:Herbal medicine Qili Qiangxin formula Hypoxia–reoxygenation Reactive oxygen species Autophagy Apoptosis AMPK/mTOR pathway 
Shexiang Tongxin Dropping Pill(麝香通心滴丸)Protects against Na2S2O4-Induced Hypoxia-Reoxygenation Injury in H9c2 Cells被引量:9
《Chinese Journal of Integrative Medicine》2019年第6期439-445,共7页LIN Shan LIN Jiu-mao ZHANG Ling CHEN Da-xin XIAO Fei CHEN Hong-wei CHEN You-qin ZHU Yu-ling CHU Jian-feng PENG Jun 
Supported by the Foundation of Fujian University of Traditional Chinese Medicine(No.X2013026);the Developmental Fund of Chen Ke-ji Integrative Medicine(No.CKJ2013016);the Education Department of Fujian Province(No.JA14163)
Objectives: To investigate the protective effects of Shexiang Tongxin Dropping Pill(麝香通心滴丸,STP) on Na2S2O4-induced hypoxia-reoxygenation injury in cardiomyoblast H9c2 cells. Methods: The cell viability and level...
关键词:myocardial ISCHEMIA apoptosis Shexiang Tongxin DROPPING PILL Chinese medicine Na2S2O4-induced HYPOXIA-REOXYGENATION injury 
Platelet-mediated adhesion facilitates leukocyte sequestration in hypoxia-reoxygenated microvessels被引量:3
《Science China(Life Sciences)》2016年第3期299-311,共13页Senfeng Zheng Yanting Cao Wenjian Zhang Honglin Liu Jia You Yiqing Yin Jinning Lou Chenghui Li 
supported by the Natural Science Foundation of Beijing City(7092093)
Leukocyte transendothelial migration and sequestration are two distinct outcomes following leukocyte adhesion to endotheli- um during ischemia-reperfusion injury, in which platelets may play a pivotal role. In the pre...
关键词:ADHESION endothelial cells HYPOXIA-REOXYGENATION leukocytes PLATELETS transendothelial migration 
Population dynamics inside cancer biomass driven by repeated hypoxia-reoxygenation cycles被引量:1
《Frontiers of Electrical and Electronic Engineering in China》2014年第3期85-99,共15页Chi Zhang Sha Cao Ying Xu 
A computational analysis of genome-scale transcriptomic data collected on -1,700 tissue samples of three cancer types: breast carcinoma, colon adenocarcinoma and lung adenocarcinoma, revealed that each tissue consist...
关键词:cancer population dynamics intratumor heterogeneity cancer cell subpopulations HYPOXIA REOXYGENATION cancer evolution 
Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathway被引量:6
《World Journal of Gastroenterology》2014年第8期2071-2078,共8页Pan Wang Yun Zeng Tao Liu Chao Zhang Pei-Wu Yu Ying-Xue Hao Hua-Xin Luo Gang Liu 
Supported by The "Eleventh Five-year Plan" for Medical Sci-ence Development of PLA,No.06MB243;the National Natural Science Foundation of China,No.81101101 and No.51273165;the Key Project of Chinese Ministry of Education,No.212149;the Projects of Sichuan Province,No.2010SZ0294,No.2011JQ0032 and No.12ZB038
AIM: To investigate the mechanisms of chloride intracellular channel 1 (CLIC1) in the metastasis of colon cancer under hypoxia-reoxygenation (H-R) conditions.
关键词:Colon cancer Intracellular chloride channel 1 HYPOXIA-REOXYGENATION Reactive oxygen species Extracellular signal-regulated kinase Cancer invasion 
Neuroprotective Effect of Chunghyuldan(Qing Xue Dan)on Hypoxia-Reoxygenation Induced Damage of Neuroblastoma 2a Cell Lines
《Chinese Journal of Integrative Medicine》2013年第12期940-944,共5页Chang-Nam Ko In-Seo Park Seong-Uk Park Woo-Sang Jung Sang-Kwan Moon Jung-Mi Park Chulhun Kang Ki-Ho Cho 
Objectives: Chunghyuldan (CHD), a combinatorial drug that has anti-hyperlipidemic and anti inflammatory activities, has been shown to reduce infarct volume in a focal ischemia-reperfusion rat model. To explore the ...
关键词:apoptosis STROKE Chunghyuldan HERBAL 
Propofol blocks apoptosis and Bcl-2 and Bax expression induced by hypoxia-reoxygenation in primary cultures of rat hippocampal astrocytes被引量:3
《Neural Regeneration Research》2009年第7期518-522,共5页Qing Li Juying Liu Long Zhou Chengming Qin 
BACKGROUND: Cerebral hippocampal astrocytes are more sensitive.to ischemic injury than neurons. Hypoxic-ischemic brain injury induces profound astrocyte apoptosis, and propofol may protect against astrocyte apoptosis...
关键词:PROPOFOL hippocampal astrocyte APOPTOSIS hypoxia and re-oxygenation BCL-2 BAX 
N-acetylcysteine blocked hypoxia-reoxygenation induced apoptosis through ROS-p38 MAPK signaling pathway in neonatal rat cardiomyocytes
《Journal of Geriatric Cardiology》2009年第3期168-172,共5页Feng-Xiang Zhang Ming-Long Chen Bing Yang Ke-Jiang Cao 
This work was supported by National Natural Science Foundation of China (No 30800464).
Objective Previous investigations have shown that N-acetylcysteine (NAC) could regulate diverse cell type's apoptosis. The purpose of this study was to evaluate the mechanism of NAC reversed apoptosis of cardiomyoc...
关键词:NAC APOPTOSIS HYPOXIA-REOXYGENATION ROS p38 
Effects and mechanism of glucagon-like peptide-1 on injury of rats cardiomyocytes induced by hypoxia-reoxygenation被引量:24
《Chinese Medical Journal》2008年第21期2134-2138,共5页XIE Yun WANG Shao-xin SHA Wei-wei ZHOU Xue WANG Wei-tin HAN Li-pin LI Dai-qing YU De-min 
Background Although the insulinotropic role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes mellitus has been substantiated, its role in cardioprotection remains largely unknown. This study aimed to determine ...
关键词:glucagon-like peptide-1 HYPOXIA-REOXYGENATION APOPTOSIS CASPASE-3 MAP kinase PI3K/AKT 
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