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作品数:32被引量:42H指数:3
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相关领域:医药卫生更多>>
相关作者:李兴启孙建和杨琳王晓磊车庆明更多>>
相关机构:广州中医药大学中国人民解放军总医院北京大学兰州大学更多>>
相关期刊:《Journal of Rare Earths》《Chinese Journal of Structural Chemistry》《Science Bulletin》《International Journal of Organic Chemistry》更多>>
相关基金:国家自然科学基金国家科技重大专项更多>>
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A novel metal-organic framework encapsulated iridium oxide nanozyme enhanced antisense oligonucleotide combo for osteoarthritis synergistic therapy
《Aggregate》2024年第6期352-366,共15页Shuqi Wu Fang Nan Kewen Zhang Wan Hao Di Shi Yang Li Wei Deng Nur Jarhen Kaixuan Li Yunyun Xiao Jun Li Xiao Lin 
Guangdong Basic and Applied Basic Research Foundation,Grant/Award Number:2023A1515030047;Natural Science Basic Research Plan in Shaanxi Province of China,Grant/Award Numbers:2024JC-YBMS-605,2024JC-YBMS-086;National Natural Science Foundation of China,Grant/Award Numbers:22367015,81672172;National Undergraduate Training Programs for Innovation and Entrepreneurship,Grant/Award Numbers:S202310699405,S202210699549。
Osteoarthritis(OA)is associated with metabolic imbalance of articular cartilage and an increase of intracellular reactive oxygen species(ROS).Synergistic therapy based on the codelivery of ROS scavengers and antisense...
关键词:antisense oligonucleotides cartilage metabolism drug delivery IrO_(2)nanozyme osteoarthritis treatment reactive oxygen species scavenging 2’ 7’-dichlorodihydrofluorescein diacetate 
Supramolecular Architectures of 2-(3-(4-acetoxyphenyl)propanoyl)benzene-1,3,5-triyl triacetate (1) and 4-(3-(4-acetoxyphenyl)propanoyl)-5-hydroxy-1,3-phenylene diacetate (2)
《International Journal of Organic Chemistry》2022年第4期200-207,共8页Li Wang Rui Xu 
2-(3-(4-acetoxyphenyl)propanoyl)benzene-1,3,5-triyl triacetate (1), C25H22O9 and 4-(3-(4-acetoxyphenyl)propanoyl)-5-hydroxy-1,3-phenylene diacetate (2), C21H20O
关键词:Phloretin Derivatives Crystal Structure Hydrogen Bonds 
Oxidative effects of glyphosate on the lipophobic intracellular environment in the microalgae Chlorella vulgaris
《BIOCELL》2022年第3期795-802,共8页JUAN MANUEL OSTERA SUSANA PUNTARULO GABRIELA MALANGA 
supported by grants from the University of Buenos Aires(UBACyT,20020170100199BA);the National Council for Science and Technology(CONICET,PIP 11220170100539CO).SP and GM are career investigators from CONICET.
The studied hypothesis is that the herbicide glyphosate(GLY)can affect the oxidative balance in the hydrophobic intracellular medium in non-target Chlorella vulgaris cells.Analytical GLY and RoundUp(RUP)supplementatio...
关键词:2’ 7’dichlorofluorescein diacetate oxidation rate Lipid soluble antioxidants Round up Redox balance 
Direct synthesis of α-hydroxyketone phosphates from terminal alkynes and H-phosphine oxides in the presence of PhI(OAc)2 and H2O被引量:1
《Chinese Chemical Letters》2016年第11期1691-1695,共5页Dong-Yan Hu Meng-Shun Li Wen-Wu Zhong Jian-Xin Ji Jin Zhu Wei Wei Qiang Zhang Ming Cheng 
financial support from the National Natural Science Foundation of China(Nos.21172213,21302109,21402184,and 21572217)
A simple and highly efficient one-pot method for the construction of α-hydroxyketone phosphates from terminal alkynes and H-phosphine oxides has been developed in the presence of PhI(OAc)2 and H20. The present prot...
关键词:α-Hydroxyketone phosphates Alkynes H-Phosphine oxides Water Phenyliodine diacetate 
Ecotoxicological effect of zinc oxide nanoparticles on soil microorganisms被引量:7
《Frontiers of Environmental Science & Engineering》2015年第5期912-918,共7页Zhaoyi SHEN Zhuo CHEN Zhen HOU Tingting LI Xiaoxia LU 
This work was supported by the National Natural Science Foundation of China (Grant Nos. 41071311, 41030529 and 41471391), Program for New Century Excellent Talents in University of Ministry of Education of China (NCET-10-0200) and YKM Entrepreneurship Education Foundation.
The widespread production and use of zinc oxide nanoparticles (ZnO-NPs) in recent years have posed potential threat to the ecosystem. This study aimed to investigate the ecotoxicological effect of ZnO-NPs on soil mi...
关键词:zinc oxide nanoparticles (ZnO-NPs) soilmicroorganisms RESPIRATION AMMONIFICATION dehydrogen-ase (DH) activity fluorescent diacetate hydrolase (FDAH)activity 
苍术聚炔类化学成分研究被引量:13
《中药新药与临床药理》2015年第4期525-528,共4页赵晋 邓金宝 黎雄 邱炳勋 黎碧华 曾星 
国家科技重大专项--重大新药创制(中药新药临床试验技术平台研究)(2012ZX09303009-003);国家自然基金青年基金(肿节风体内入血成分及其抗炎作用机理研究)(81202888)
目的研究苍术中聚炔类化学成分。方法采用开放ODS柱色谱及制备液相色谱等分离技术,根据化合物的理化性质和光谱数据鉴定其结构。结果从苍术80%乙醇提取物部分共分离7个聚炔类成分,分别鉴定为12,14-diacetate-2E,8E,10E-trien-4,6-diyn-1...
关键词:苍术 化学成分 聚炔类 12 14-diacetate-2E 8E 10E—trien-4 6-diyn-1-ol (2Z 4E 10E)-dodeca-2 4 10-trien-6 8-diynyl acetate 
Highly Efficient, One Pot Synthesis and Oxidation of Hantsch 1,4-Dihydropyridines Mediated by Iodobenzene Diacetate (III) Using Conventional Heating, Ultrasonic and Microwave Irradiation
《International Journal of Organic Chemistry》2014年第3期174-181,共8页Khalid Hussain Deepak Wadhwa 
A mild, general, convenient, and efficient one-pot synthesis of 4-arylpyridines (4) is described using conventional heating, ultrasound and microwave irradiation. Aryl aldehydes (2) were efficiently condensed with eth...
关键词:DIHYDROPYRIDINES IODOBENZENE DIACETATE ULTRASONIC Microwave One-Pot Formylpyrazoles 
Synthesis and X-Ray Structure of Important Anticancer Nucleosides Intermediate (2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i>)-2-(acetoxymethyl)-5- (3-bromo-5-(methoxycarbonyl)- 1<i>H</i>-1,2,4-triazol-1-yl)tetrahydrofuran- 3,4-diyl Diacetate被引量:1
《Journal of Crystallization Process and Technology》2014年第3期140-144,共5页Yang Liu Guanghui Tian Hongguang Ge Xiaoyan Cao Daihua Hu Dehua Zhang 
An important anticancer nucleosides intermediate (2R,3S,4S,5R)-2-(acetoxymethyl)-5-(3-bromo-5-(methoxycar-bonyl)-1H-1,2,4-triazol-1-yl)tetrahydrofuran-3,4-diyl diacetate was synthesized by directly coupling the bromot...
关键词:ANTICANCER NUCLEOSIDES INTERMEDIATE Triazole NUCLEOSIDES 
Synthesis of 3,5-diarylisoxazoles under solvent-free conditions using iodobenzene diacetate
《Chinese Chemical Letters》2013年第12期1045-1048,共4页Kondapalli Venkata Gowri Chandra Sekhar Thripuraribhatla Venkata Naga Varuna Tara Sasank Hunsur Nagendra Nagesh Narva Suresh Kalaga Mahalakshmi Naidu Amaroju Suresh 
The fnancial assistance provided by DST (under Fast Track scheme: SR/FT/CS-076/2009), New Delhi, India
A simple and efficient method has been developed for conversion of chalcone oximes to 3,5-diaryl isoxazoles in excellent yields under solvent-free conditions. The synthesized compounds were characterized by infrared s...
关键词:lsoxazoles Chalcones Solid-state synthesis lodobenzene diacetate 
Cell Viability of Byrsonima intermedia A Juss Calli
《Journal of Agricultural Science and Technology(B)》2012年第6期713-720,共8页Luciano Coutinho Silva Renato Paiva Daiane Peixoto Vargas Diogo Pedrosa Correa da Silva Rairys Cravo Herrera Sandro Barbosa Antonio Paulino da Costa Netto 
Byrsonima intermedia A Juss. is a species with pharmacological properties from the Brazilian Cerrado that shows difficulties related to sexual propagation. Research on cell viability may provide useful information for...
关键词:Cell viability fluorescein 3 6-diacetate 2 3 5-tripheniltetrazolium chloride SUBCULTURE tissue culture native plant. 
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