DIHYDROPYRIDINES

作品数:13被引量:14H指数:2
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相关领域:理学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Science China Chemistry》《Open Journal of Synthesis Theory and Applications》《International Journal of Organic Chemistry》更多>>
相关基金:国家自然科学基金天津市自然科学基金北京市自然科学基金更多>>
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Synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N‑heteroarenes with 4-glycosyl-dihydropyridines被引量:2
《Science China Chemistry》2020年第11期1613-1618,共6页Qingbing Wang Juan Duan Pingping Tang Gong Chen Gang He 
This work was supported by the National Natural Science Foundation of China(21672105,21725204,91753124);Natural Science Foundation of Tianjin(17JCYBJC19700,18JCZDJC32800);the Fundamental Research Funds for the Central Universities(Nankai University)(63191746).
A radical-mediated method was reported for diastereoselective synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-1,4-dihydropyridine(DHP)reagents.These DHP...
关键词:non-classical C-glycoside Minisci reaction 4-gIycosyl-dihydropyridine 
A Novel Dihydropyridines C-Glycosylated Compound by Hantzsch Cyclo-Condensation
《Open Journal of Synthesis Theory and Applications》2018年第2期17-29,共13页Soheila Sedaghat Shabnam Madjdpour 
The Hantzsch synthesis has been used for the preparation of the 1,4-Dihydropyridines compounds with different pharmacophore groups. The use of a designed glycosylated compound in Hantzsch synthesis would lead to a nov...
关键词:1 4-Dihydropyridines c-Glycosylated Multi Component REACTION HANTZSCH REACTION 
New generations of dihydropyridines for treatment of hypertension被引量:3
《Journal of Geriatric Cardiology》2017年第1期67-72,共6页Angela L Wang Costantino Iadecola Gang Wang 
Since the calcium channel blocker (CCB) has become one of the most prescribed agents for antihypertensive monotherapy in the world, this brief review will focus on the recent research and development of the dihydrop...
关键词:Central nervous system Dihydropyridine HYPERTENSION Voltage-gated calcium channel blocker 
An Environmentally Benign Catalytic Method for Versatile Synthesis of 1,4-Dihydropyridines via Multicomponent Reactions
《Chinese Journal of Chemistry》2015年第5期568-572,共5页Shuo Cao Shanshan Zhong Changfeng Hu Jie-Ping Wan Chengping Wen 
the Department of Education of Jiangxi Province(No.GJJ13245);the Open Research Project from College of Basic Medical Sciences,Zhejiang Chinese Medical University and a Innovative Program of Graduate Students of Jiangxi Province(No.YC2014-S158).
The synthesis of diverse 1,4-dihydropyridines have been achieved via the multicomponent reactions of aldehydes,enaminones and amines.The reactions have been smoothly performed in water to provide all products with mod...
关键词:lactic acid catalysis multicomponent reactions 1 4-dihydropyridines green catalysis HETEROCYCLE 
Highly Efficient, One Pot Synthesis and Oxidation of Hantsch 1,4-Dihydropyridines Mediated by Iodobenzene Diacetate (III) Using Conventional Heating, Ultrasonic and Microwave Irradiation
《International Journal of Organic Chemistry》2014年第3期174-181,共8页Khalid Hussain Deepak Wadhwa 
A mild, general, convenient, and efficient one-pot synthesis of 4-arylpyridines (4) is described using conventional heating, ultrasound and microwave irradiation. Aryl aldehydes (2) were efficiently condensed with eth...
关键词:DIHYDROPYRIDINES IODOBENZENE DIACETATE ULTRASONIC Microwave One-Pot Formylpyrazoles 
The SBA-15/SO_3H nanoreactor as a highly efficient and reusable catalyst for diketene-based,four-component synthesis of polyhydroquinolines and dihydropyridines under neat conditions被引量:1
《Chinese Chemical Letters》2013年第5期401-403,共3页Sadegh Rostamnia Fatemeh Pourhassan 
An efficient diketene ring-opening synthesis of polyhydroquinoline derivatives using SBA-15 sulfonic acid modified mesoporous substrates a green and reusable catalyst in a single-pot four-component coupling reaction o...
关键词:SBA-15/SO3H NANOREACTOR Diketene POLYHYDROQUINOLINE 
MgO Nanoparticles as a Recyclable Heterogeneous Catalyst for the Synthesis of Polyhydroquinoline Derivatives under Solvent Free Conditions被引量:2
《Chinese Journal of Chemistry》2011年第8期1624-1628,共5页Ranjbar-Karimi, Reza Hashemi-Uderji, Somayeh Bazmandegan-Shamili, Alireza 
Magnesium oxide nanopartticels in average size between 35--120 nm were prepared by sonochemistry method. Synthesis of polyhydroquinoline derivatives using MgO nanoparticles from the reaction of dimedone, benzaldehyde ...
关键词:multicomponent reaction CYCLIZATION nanoparticle magnesium oxide POLYHYDROQUINOLINE DIHYDROPYRIDINES ALDEHYDE 
Activated Anilide in Heterocyclic Synthesis: Synthesis of New Dihydropyridines, Dihydropyridazines and Thiourea Derivatives被引量:3
《Chinese Journal of Chemistry》2011年第6期1154-1162,共9页Hafiz, Ibrahim S. A. Ramiz, Mahmoud M. M. Sarhan, Ahmed A. M. 
A series of new dihydropyridines, butanamide, dihydropyridazines and thiourea derivatives have been prepared through the reactions of 3-aminopyridine (1) and N-(pyridin-3-yl)-3-(pyridin-3-ylimino)butanamide 3 wi...
关键词:LACTONES oxygen heterocycles cis-Wittig olefination mono and di-O-benzyl ethers cryptofolione stereoisomers 
Multicomponent synthesis of dihydropyridines catalyzed by L-proline被引量:2
《Chinese Chemical Letters》2011年第5期531-534,共4页Leila Zare Mohammad Nikpassand 
support from the Research Council of Islamic Azad University-Rasht Branch
Multicomponent synthesis of mono and bis 4-substituted-1,4-dihydropyridines from aldehydes,dimedone and ammonium acetate in the presence of an efficient recyclable catalyst,L-proline,in high yield and short reaction t...
关键词:MULTICOMPONENT DIHYDROPYRIDINES DIMEDONE L-PROLINE 
The influence of dihydropyridines calcium antagonists on 5-HT-induced intracellular calcium signal
《Science China Chemistry》2007年第4期562-567,共6页WANG ShuMin GUAN HuaShi FANG Yi MA Ping SUN JianZi LIU LiHong 
Confocal laser scanning microscopy (CLSM) was applied to detect the intracellular [Ca2+] variety of fluorescent intension, with Fluo-3/AM fluorescence loaded in SFSMC. The results show that 10 μmol/L Lacidipine can r...
关键词:LACIDIPINE calcium SPARKS STOMACH FUNDUS smooth muscle cells confocal laser scanning microscopy 
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