A.S.would like to acknowledge the financial support from the Canadian Institutes of Health Research(CIHR)through a postdoctoral fellowship as well as the startup fund from The Pennsylvania State University;A.K.would like to acknowledge funding from the National Institutes of Health(1R01EB023052,1R01HL140618,CA257558,DK130566).We acknowledge UCLA CFAR grant 5P30 AI028697 and the UCLA AIDS Institute.The authors thank Profs.S.Li and M.Butte at UCLA for providing cryo-sectioning equipment and lab space for the blood coagulation tests,respectively.The authors also thank Prof.K.J.Lee for his advice on microneedle fabrication.
Blood loss by hemorrhaging wounds accounts for over one-third of~5 million trauma fatalities worldwide every year.If not controlled in a timely manner,exsanguination can take lives within a few minutes.Developing new ...
supported by the China Agriculture Research System(No.CARS-18-ZJ0102);National Natural Science Foundation of China(Nos.52103096,51803170,51803171,and 81703424);Natural Science Foundation of Chongqing,China(grant number cstc2020jcyj-msxmX0383);Fundamental Research Funds for the Central Universities(2020CDJQY-A041).
Complex yet lethal wounds with uncontrollable bleeding hinder conventional hemostats from clotting blood at the source or deep sites of injury vasculature,thereby causing massive blood loss and significantly increased...
jointly supported by the National Natural Science Foundation of China(grant numbers:51973172,and 51673155);the Natural Science Foundation of Shaanxi Province(No.2020JC-03 and 2019TD-020);State Key Laboratory for Mechanical Behavior of Materials,and the Fundamental Research Funds for the Central Universities;the World-Class Universities(Disciplines)and the Characteristic Development Guidance Funds for the Central Universities;Opening Project of Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research,College of Stomatology,Xi’an Jiaotong University(No.2019LHM-KFKT008);the Key R&D Program of Shaanxi Province(No.2019ZDLSF02-09-01,2020GXLH-Y-019);Innovation Capability Support Program of Shaanxi Province(Program No.2019GHJD-14,2021TD-40);Scientific Research Program Funded by Shaanxi Provincial Education Department(Program No.18JC027).
With the increasing prevalence of drug-resistant bacterial infections and the slow healing of chronically infected wounds,the development of new antibacterial and accelerated wound healing dressings has become a serio...
Aim: To examine the changes in electrolyte concentrations after addition of zeolite-based hemostat QuikCIot in blood and the effects of zeolite on blood coagulation in vitro. Methods: Fresh blood was taken from heal...
Gastrointestinal (GI) bleeding refers to any hemorrhage ascribed to the pathologies of the gastrointestinal tract,extending from the mouth to the anal canal.Despite the recent improvements in the endoscopic,hemostatic...
Reliability of medical instruments such as hemostats is extremely important because these instruments are used in patients who are in critical condition. Clamping force of hemostats, as an important parameter of hemos...