ANTI-PROLIFERATIVE

作品数：51被引量：105H指数：5
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The combination of sitagliptin and bee honey extract potentiates the anti-proliferative properties of 5-fluorouracil on Caco-2 cell line without detectable inflammatory events
《Clinical Traditional Medicine and Pharmacology》2024年第4期65-75,共11页Asmaa Eisa Mohamed F.Elshal Shaden Muawia Hany Khalil 
Background:Colon cancer originates in the colon,specifically the large intestine.It carries a poor prognosis and high mortality rate due to late diagnosis and migration.Objective:Here our objective was to evaluate the...
关键词：Colon cancer Caco-2 cells 5-flourouracil SITAGLIPTIN Bee honey Raf-1 signaling Programmed cell death Cytokines 
Anti-proliferative effect of Annona extracts on breast cancer cells被引量：2
《BIOCELL》2023年第8期1835-1852,共18页MARIA-LUISA VEISAGA MARIAM AHUMADA STACY SORIANO LEONARDO ACUNA WEI ZHANG IVY LEUNG ROBERT BARNUM MANUEL A.BARBIERI 
supported by the National Institutes of Health Grant SC1DK084343(to MAB);by Mass Spectrometry Research and Education Center must cite funding from NIH S10 OD021758-01A1.
Backgorund:Fruits and seed extracts of Annona montana have significant cytotoxic potential in several cancer cells.This study evaluates the effect of A.montana leaves hexane extract on several signaling cascades and g...
关键词：Annona montana Cancer cell lines Apoptosis ANTI-PROLIFERATIVE Cell cycle AKT MTOR 
Characterization and antimicrobial,antioxidant,and anti-proliferative activities of green synthesized magnesium oxide nanoparticles with shoot extracts of Plicosepalus curviflorus被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2023年第7期315-324,共10页Reem Hamoud Alrashoudi Manal Abudawood Ayesha Mateen Hajera Tabassum Noura Ibrahem Alghumlas Sabiha Fatima Basmah Almaarik Farah Maqsood Nawal M.Al Musayeib Musarat Amina 
funded by the Researchers Supporting Project Number(RSPD2023R656);King Saud University;Riyadh;Saudi Arabia。
Objective:To synthesize magnesium oxide nanoparticles using ethanol extract of shoots of Plicosepalus curviflorus(PC-MgONPs)and evaluate the antimicrobial,antioxidant,and anti-proliferative activities of PC-MgONPs.Met...
关键词：PC-MgONPs Plicosepalus curviflorus FTIR ANTIMICROBIAL Cell viability ANTIOXIDANT 
Anti-Biofilm, Anti-Quorum Sensing, and Anti-Proliferative Activities of Methanolic and Aqueous Roots Extracts of Carica papaya L. and Cocos nucifera L.
《Advances in Microbiology》2023年第4期165-180,共16页Wendkouni Leila Marie Esther Belem-Kabré Vincent Ouédraogo Bagora Bayala Alimata Bancé Estelle Ouédraogo Boubacar Yaro Lazare Belemnaba Moussa Compaoré Martin Kiendrébeogo Noufou Ouédraogo 
Objective: This study focused on the antibacterial and anti-proliferative activity of extracts from Carica papaya and Cocos nucifera roots. Methodology: The minimum inhibitory concentration and the minimum bactericida...
关键词：Triterpenes and Sterols Content Antibacterial Biofilm Quorum Sensing ANTI-PROLIFERATIVE Medicinal Plants 
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 proteineprotein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells被引量：2
《Genes & Diseases》2022年第6期1674-1688,共15页Shasha Cheng Guan-Jun Yang Wanhe Wang Dik-Lung Ma Chung-Hang Leung 
This work was supported by the Health and Medical Research Fund(No.HMRF/14150561);the National Natural Science Foundation of China(No.201575121 and 21775131);the Hong Kong Baptist University Century Club Sponsorship Scheme 2020,Teaching Development Fund(No.TDG/1920/02);the Science and Technology Development Fund,Macao SAR,China(File no.0072/2018/A2 and 0007/2020/A1);SKLQRCM(UM)-2020-2022;the University of Macao,China(MYRG2019e00002eICMS).
Triple-negative breast cancer(TNBC)is a highly aggressive and metastasizing cancer that has the worst prognosis out of all breast cancer subtypes.The epithelial emesenchymal transition(EMT)and cancer stem cells(CSCs)h...
关键词：Cancer stem cells CDK9-cyclin T1 Epithelial mesenchymal transition Proteineprotein interaction(PPI) Triple-negative breast cancer(TNBC) 
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory,anti-oxidative and anti-proliferative effects被引量：3
《Acta Pharmacologica Sinica》2022年第10期2573-2584,共12页Chao Ye Zhi Geng Ling-li Zhang Fen Zheng Ye-bo Zhou Guo-qing Zhu Xiao-qing Xiong 
This work was supported by National Nature Science Foundation of China(81600323&81970356).
Inflammatory activation and oxidative stress promote the proliferation of vascular smooth muscle cells(VSMCs),which accounts for pathological vascular remodeling in hypertension.ELABELA(ELA)is the second endogenous li...
关键词：ELABELA peptide HYPERTENSION proliferation vascular remodeling inflammation oxidative stress 
Anti-proliferative Properties of Schinensilactone A,A Schinortriterpenoid with 7,8-Seco-1,8-cyclo Scaffold against Caco-2 by Inducing Cell Apoptosis from the Leaves of Schisandra chinensis被引量：3
《Chinese Journal of Chemistry》2022年第11期1331-1336,I0002,共7页Yan Liu Guo-Zhen Liu Xiao-Mao Li Peng Jiang Yong-Gang Xia Hai-Xue Kuang Bing-You Yang 
This work was financially supported by the_Heilongjiang Touyan Innovation Team Program and the National Natural Science Foundation of China(NSFC)(81473325).
A novel schinortriterpenoid(SNT),schinensilactone A(1),characterized by a unique 7,8-seco-1,8-cyclo-schisanartane scaffold,was isolated from the leaves of Schisandra chinensis(Turcz.)Baill,together with a new SNT(schi...
关键词：Schinensilactone A Schinensilactone B Natural products TERPENOIDS Biological activity 
Prodigiosin from Serratia:Synthesis and potential applications被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2022年第6期233-242,共10页Sami Mnif Marwa Jardak Brahim Bouizgarne Sami Aifa 
Prodigiosin is a red pigment with a pyrrolylpyrromethane skeleton.It is mainly produced by bacterial strains belonging to the Serratia genus,but also by some other genera,including Streptomyces and Vibrio.Within the g...
关键词：PRODIGIOSIN SERRATIA SYNTHESIS METABOLITES Biological activities Applications ANTIMICROBIAL ANTI-PROLIFERATIVE 
Secretome-microRNA and anti-proliferative APRO family proteins as cancer prevention and stem cell research strategies
《BIOCELL》2022年第5期1163-1167,共5页YUKA IKEDA NOZOMI NAGASE AI TSUJI KURUMI TANIGUCHI YASUKO KITAGISHI SATORU MATSUDA 
Stemness of cancer cells contains limitless self-renewal proliferation.For the purpose of proliferation,secretome might exert its effects via the paracrine signaling.Specific microRNAs enclosed in the secretome of can...
关键词：Cancer Stem cell SECRETOME PROLIFERATION APRO family MICRORNA 
Identification of novel bioactive proanthocyanidins with potent antioxidant and anti-proliferative activities from kiwifruit leaves
《Food Bioscience》2022年第2期539-549,共11页Ji-Min Lv Mostafa Gouda Alaa El-Din Bekhit Ya-Ke He Xing-Qian Ye Jian-Chu Chen 
This study was supported by the National Key Research and Development Program of China(grant no:2017YFD0400704).
Agro-wastes contribute major social,economic,and environmental challenges for food production and circular economy systems.The current increasing demand for clean label food production and use of natural bioactive com...
关键词：PROANTHOCYANIDINS Agro-waste valorisation HPLC-QTOF-MS/MS Antioxidant potential Anti-proliferative activity 
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